Sidika Karakas, M.D.: Dr. Karakas's research focuses on the effects of diet and nutrients on hormones, obesity, insulin resistance, lipid disorders, inflammation and reproductive disorders associated with Polycystic ovarian syndrome (PCOS).
Dr. Karakas believes that early diagnosis of PCOS and insulin resistance during adolescence can prevent type 2 diabetes and other advanced symptoms of PCOS in adulthood. She is currently conducting a study entitled School Based Screening to Identify the Adolescent s at Risk for Type 2 Diabetes Mellitus. Her goal is to make this a part of the routine health care screening in high schools.
Lars Berglund, M.D., Ph.D.: Dr. Berglund’s research focus is in the area of lipoprotein metabolism and cardiovascular disease and his research is funded by NHLBI. He has published more than 170 peer-reviewed papers and is a member of the Editorial Board of Arteriosclerosis, Thrombosis and Vascular Biology, the Journal of Clinical Endocrinology and Metabolism, and Metabolic Syndrome and Related Disorders. He is a member of the NIH AIDS, Clinical Research and Epidemiology (ACE) study section, the American Heart Association Peer Review Committee and the Clinical Guidelines subcommittee of the Endocrine Society.
Enkhmaa Byambaa, M.A.S., M.D., Ph.D.: Dr. Byambaa's research interest is focused on risk factors for cardiovascular diseases (CVD), including metabolic syndrome, genetics and lipid and lipoprotein metabolism in various ethnic/racial groups. A major interest has been to identify factors that impact on Lipoprotein(a), Lp(a), a genetically regulated cardiovascular risk factor.
Her current research projects: to test the suitability of rhesus monkey as a model system for studies on Lp(a), to assess the roles of inflammation, endocrine dysregulation, HIV disease activity and antiretroviral therapy in modulating Lp(a) levels and associated atherogenic properties, and to identify genetic determinants of Lp(a) levels in humans.
Prasanth Surampudi, M.D.: Dr. Surampudi's current research interests center around a) Male Reproductive Endocrinology, b) Diabetes & Metabolism c) Risk factor reduction in Cardiovascular Disease and d) Neuromuscular Endocrinology.
John Yoon, M.D., Ph.D.: Dr. Yoon is interested in molecular studies of metabolic regulation and human disease, with a particular focus on diabetes mellitus. Ongoing work utilizes a combination of experimental systems and approaches to investigate the role of specific intracellular signaling pathways such as the Wnt pathway in the regulation of muscle metabolism and their impact on physiological and pathological adaptations.
Another area of interest is the contribution of mitochondrial defects and inflammatory processes to the development of metabolic disease. Large-scale genetic screens in muscle cells have been performed to isolate regulators of mitochondrial function and some of the identified genes are being characterized.