Demosthenes Pappagianis, M.D., Ph.D.
Tupper Hall
Room 3145
Davis Campus

Medical mycology and bacteriology; coccidioidomycosis: infections of humans, immunology-vaccines, chemotherapy, experimental pathology; epidemiology, candidiasis

Lunetta, J. M., S.M. Johnson and D. Pappagianis. Molecular cloning, characterization and expression of two β-N-acetylhexosaminidase homologs of Coccidioides posadasii. Medical Mycology 2010 Aug;48:744-756

Kuberski, T., Herrig, J., and Pappagianis, D. False positive IgM Serology in Coccidioidomycosis. Journal of Clinical Micro 2010 Jun;48:2047-2049.

Nesbit, L., S.. M. Johnson, D. Pappagianis, and N.M. Ampel. Polyfunctional T lymphocytes are in the peripheral blood of donors naturally immune to coccidioidomycosis and are not induced by dendritic cells. Infection and Immunity 2010 Jan;78:309-15.

Stevens, D. A., Clemons, K. V., Levine, H. B., Pappagianis, D., Baron, E.J., Hamilton, J. R. Expert Opinion: What to do when there is Coccidioides exposure in a laboratory. Clinical Infectious Diseases 2009 Sep 15;49:919-23.

Barry, C.D., Stevens, D. A., Hassid, E. I., Pappagianis, D., Happs, E. L., Sahrakar, K. A new method for the treatment of chronic fungal meningitis; continuous infusion into the cerebrospinal fluid for coccidioidal meningitis. Amer Journal Med. Sci. 2009 Jul;238:79-82.

Pappagianis, D. Current status of serologic studies in coccidioidomycosis. Current Fungal Infection Reports 2007;1:129-134.

Lunetta, J. M., K. A. Simmons, S.M. Johnson, and D. Pappagianis. Molecular cloning and expression of a cDNA encoding a Coccidioides posadasii Cu, Zn superoxide dismutase identified by proteomic analysis of the coccidioidal T27K. Ann NY Acad Sci. 2007 Sep;1111:181-97.

Johnson, S.M., N. W. Lerche, D. Pappagianis, J. L. Yee, J.N. Galgiani and R. F. Hector. Safety antigenicity, and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus macaques (Macaca fascicularis). Ann NY Acad Sci. 2007 Sep;1111:290-300.

Johnson, S.M., K.M. Kerekes, J.M. Lunetta and D. Pappagianis. Characteristics of the protective subcellular T27K vaccine. Ann NY Acad Sci. 2007 Sep;1111:290-300.

Lunetta, J.M., K. A. Simmons, S. M. Johnson and D. Pappagianis. Molecular cloning and expression of a cDNNA encoding a Coccidioides posadasii 1,2-alpha-mannosidase identified in the coccidioidal T2TK by immunoproteomic methods. Ann NY Acad Sci. 2007 Sep;1111:164-80.

Papagianis, D. and Coccidioidomycosis Serology Laboratory. Coccidioidomycosis in California State Correctional Institutions. Ann NY Acad Sci. 2007 Sep;1111:103-11.

Pappagianis, D., Coccidioidomycosis. In “Textbook of Pediatrics” 18th Edition, R. M. Kliegman, R. E. Behrman, H. B. Jensen, B. F. Stanton (Eds)Saunders Co., Chapter 237, pp. 1319 – 1322. 2007

Pappagianis, D. Coccidioides immitis. In Topley & Wilson’s Microbiology and Microbial Infections, Fifth Edition, Volume 4, Medical Mycology. R. J. Hay, W. Merz, (Eds), Hodder Arnold Publishers, Inc. Chapter 28. 2005

Ampel, N. M., Nelson, D.K., Chavez, S., Naus, K. A., Herman, a.B., Li L., Simmons, K. A., Pappagianis, D. Preliminary evaluation of whole-blood gamma interferon release for clinical assessment of cellular immunity in patients with active coccidioidomycosis. Clin Diagn Lab Immunol., 2005 Jun;12(6):700-4.

Ampel, N. M., Nelson, D.K., Li L., Dionne, S. O., Lake, D. F., Simmons, K. A., Pappagianis, D. The mannose receptor mediates the cellular immune response in human coccidioidomycosis. Infec Immun 2005 Apr;73(4):2554-5.

Sorensen, K.N., R.A. Sobel, K.V. Clemons, D. Pappagianis, D.A. Stevens, and P.L. Williams. Comparison of fluconazole and itraconazole in a rabbit model of coccidioidal meningitis. Antimicrobial Agents and Chemotherapy. 2000 Jun;44:1512-1517.

Cairns, L.D. Blythe, A., Kao, D. Pappagianis, L. Kaufman, J., Kobayashi and R. Hajjeh. Outbreak of coccidioidomycosis in Washington State residents returning from Mexico. Clinical Infectious Diseases 2000 Jan;30:61-64.

Johnson, S.M., K.M. Kerekes, C.R. Zimmermann, R.H. Williams, and D. Pappagianis. Identification and cloning of an aspartyl proteinase from Coccidioides immitis. GENE 2000 Jan 11;241:213-222.

Pappagianis, D. Coccidioidomycosis. In: "Textbook of Pediatrics" 16th Edition, R.E. Behrman, R.M. Kliegman, H.B. Jensen (Eds.) Saunders Co., Chapter 236, pp. 942-944. (Revised edition of #66) 1999

Pappagianis, D. Coccidioides immitis Antigen. Journal of Infectious Diseases, 1999 Jul;180:243-244.

Zimmermann, C.R., Johnson, S.M., Martens, G.W., White, A.G., Zimmer, B.L. and Pappagianis, D. Protection against lethal murine coccidioidomycosis by a soluble vaccine from spherules. Infection and Immunity, 1998 May;66: 2342-2345.