Evaluating Phenotype of Down Syndrome and ADHD for Future Assessment and Medication Treatment
Children with Down syndrome (DS) have a greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing children. Despite this higher risk, we do not have a solid understanding of the relationship between DS and ADHD. There is uncertainty regarding how to accurately diagnose ADHD in children with DS. Our study seeks to define the clinical features of DS+ADHD to enable a more accurate diagnosis.
What does participation involve?
The study consists of one Phenotyping visit at the UC Davis MIND Institute during which each child will complete cognitive and behavioral assessments. This visit will take about 90 minutes to complete. In addition, each child’s parent/caregiver will complete eight parent-report forms and one parent interview. We will request a teacher/aide complete five teacher-report forms online to provide information about the effects of ADHD on children with DS.
In response to the COVID-2019 pandemic, the parent interview can either be completed in-person during the study visit; or it can be completed virtually within one week of the study visit. The child’s parent/caregiver will decide which mode of administration he or she would prefer, and the study team will make the proper accommodations and provided additional resources as needed.
Eligibility
- Have a documented diagnosis of Down Syndrome
- Ages 6-17 years old
What else can I expect?
- Comprehensive diagnostic assessment, including intelligence, behavioral and cognitive assessments
- $50 gift card for families completing the Phenotype Visit
- $20 gift card for the teacher/aide completing the Phenotyping Teacher Forms
- There is no cost associated with study participation
Contact Us
If you have any questions regarding this study, please contact Danielle Ponzini at 916-703-0484
Principal Investigator:
Kathleen Angkustsiri, M.D., M.A.S.
Associate Professor of Clinical Pediatrics