Endometrial Cancer

The American Cancer Society’s estimates for uterus cancer (both endometrial cancer and uterine sarcomas) in the United States for 2013:

  • About 49,560 new cases of cancer of the body of the uterus
  • About 8,190 deaths from cancers of the uterine body

In this country, cancer of the endometrium is the most common cancer found in women’s reproductive organs. The chance of a woman having this cancer during her lifetime is about one in 38 (about 3% lifetime risk).

Cervical Cancer

The American Cancer Society's estimates for cancer of the cervix in the United States for 2013:

  • About 12,340 new cases of invasive cervical cancer (cancer that has spread beyond the cervix)
  • About 4,030 deaths from cervical cancer

Most cervical cancer is preceded by a pre-cancerous state, providing an opportunity for early detection and eradication. When found and treated early, cervical cancer often can be cured.

Cervical cancer was once one of the most common causes of cancer death for American women. But after 1955 the death rate from cervical cancer went down a lot. The main reason for this change is the use of screening to find cervical cancer early.

Ovarian/Uterine Cancer

The American Cancer Society’s estimates for ovarian cancer in the United States for 2013:

  • About 22,240 new cases of ovarian cancer
  • About 14,230 deaths from ovarian cancer

Ovarian cancer is the ninth most common cancer in women (not counting skin cancer). It ranks fifth as the cause of cancer death in women.  Because most patients present with advanced stage disease, it has a very high case-fatality rate compared to other cancers.  It is more common in white women than African-American women. About half of the women diagnosed with ovarian cancer are 63 years or older.

A woman’s risk of getting invasive ovarian cancer in her lifetime is about 1 in 72 (1.4% lifetime risk). Her lifetime chance of dying from invasive ovarian cancer is about 1 in 100.

Fallopian Tube Cancer

Fallopian tube cancer is relatively uncommon, representing about 1 to 2 percent of all gynecologic cancers.  The origins of fallopian tube cancer are probably closely tied to that of ovarian cancer.  Emerging theories of pathogenesis suggest that fallopian tube cancer may actually be responsible for more than 50% of high-grade serous cancers of the ovary.  The overall treatment plan closely follows that of ovarian cancer, except that Stage I cancers have a better prognosis compared to ovarian cancer.

Other less common gynecologic cancers include:

  • Vulvar cancer
  • Vaginal cancer
  • Gestational trophoblastic disease