Two UC Davis Health experts featured in national medical journal


Not one but two UC Davis Health experts have commentaries out today in Aug. 4 issue of the Annals of Internal Medicine, the flagship journal of the American College of Physicians.

Nancy Lane discusses a new study published in the journal about a drug that appears to have provided unexpected but significant benefits for those facing knee or hip replacements.

A distinguished professor of medicine and rheumatology, Lane is internationally known for her work in osteoporosis and osteoarthritis. She highlights the research, which was done as a secondary analysis of osteoarthritis data from a national cardiovascular disease study (CANTOS). It tested the medication Canakinumab for its possible benefits.

Lane’s commentary, titled “A Promising Treatment for Osteoarthritis?”, says the unexpected findings deserve more investigation as a potential disease-modifying osteoarthritis drug. She says further studies should evaluate the importance of the C-reactive protein, an elevated biomarker that is a factor in the systemic and localized inflammation that characterizes osteoarthritis.

Lane, who also directs the UC Davis Center for Musculoskeletal Health, emphasizes that any upcoming studies should include more women as participants to better reflect the osteoarthritis population and ensure more robust results.

Garen Wintemute, professor of emergency medicine and director of the UC Davis Violence Prevention Research Program, talks about violence and social change in his commentary. He urges health professionals to help address the nation’s social disparities, which he says threaten not only public health but also a free society. 

Wintemute notes that the coronavirus epidemic is driving an increase in violence, particularly firearm violence.

“That violence, like the pandemic itself, is shining a powerful spotlight on stark disparities and lethal abuses of power…” says Wintemute. “For compelling reasons, we are now focused sharply on disparities in the risk for violence by race and ethnicity.”

His commentary includes suggestions for health professionals who want to become more proactive about saving lives and restoring communities to health.

“Such work in the present moment is how we honor the past and pay our debt to the future,” says Wintemute.