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SYNTHESIS- Logo
A publication  of the UC Davis Cancer Center
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  N E W S
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"" Benefactors
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"" Calendar of Events
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"" News
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"" First cancer research endowment established
"" Toward a test for ovarian cancer
"" New drug extends lung cancer survival 22 percent
  Portal to health
  Nigerian-born veterinarian wins award to support cancer research
  Novel compound targets leukemia and lymphoma cells
  Snacks and kids' health
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"" Planned Rocklin facility to offer outpatient cancer treatment
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"" Cancer help in Vietnamese
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"" Do women who take tamoxifen to
prevent breast cancer live longer?
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"" $3.3 million for basic science research in cancer
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"" Joyce Raley Teel Award
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"" Honoring survivors
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"" Otto honored
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Current Issue: VOLUME 8. NO 2. SPRING/SUMMER 2006
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NEWS
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Novel compound targets leukemia and lymphoma cells

UC Davis Cancer Center researchers have developed a novel peptide that binds to the surface of leukemia and lymphoma cells with extremely high affinity, specificity and stability, and demonstrates remarkable promise as a tool to help image tumors and deliver anti-cancer drugs. The research was reported in the July issue of Nature Chemical Biology.

"We believe this peptide has great potential for becoming a new, effective imaging and therapeutic agent for patients with lymphoid cancers" said Kit Lam, professor and chief of hematology and oncology and senior author of the paper.

The peptide — named LLP 2A — binds to a receptor found on the surface of lymphocytes. Lam's next step will be to evaluate the binding of LLP 2A in a larger number of human lymphoma biopsy samples. If those results are positive, Lam plans to test the peptide as a lymphoma-imaging agent in patients.

Experiments are already under way at the School of Veterinary Medicine to evaluate LLP 2A in dogs with naturally occurring non-Hodgkin's lymphoma.

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UC DAVIS CANCER CENTER
4501 X Street
Sacramento, CA 95817

cancer.center@ucdmc.ucdavis.edu

© 2006 UC Regents. All rights reserved.

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