Harold Burger, M.D., Ph.D.
- Professor of Medicine in Residence
Philosophy of Care
Respect for patients
Dr Burger's research interests include: HIV research, in particular HIV tropism and other determinants of HIV pathogenesis and disease progression.
Six Patents on:
"Analysis of HIV-1 Coreceptor Use in the Clinical Care of HIV-1 Infected Patients," and "Heteroduplex Tracking Assay," US Patents 2004, 2007, 2008, 2010, 2011
The patented technologies are licensed to Quest Diagnostics and serve as the basis for its clinical test, "HIV-1 Coreceptor Tropism Assay."
Patents and licenses are owned by Health Research Inc.
M.D., Albert Einstein College of Medicine, Bronx NY 1978
Ph.D., Virology, The Rockefeller University, New York NY 1976
B.S., University of Chicago, Chicago IL 1969
Internship: Montefiore Hospital Medical Center, Bronx NY 1978-1979
Montefiore Hospital Medical Center, Bronx NY 1979-1980
Stanford University Hospital, Stanford CA 1980-1981
Infectious Disease, Stanford University Medical Center, Stanford CA 1981-1985
American Board of Internal Medicine, 1981
Medical Board of California, 2015
American Society for Microbiology
Honors and Awards
Leo Davidoff, M.D., Teaching Award, Montefiore Hospital, New York, 1980
Clinical Investigator Award, National Heart Lung and Blood Institute, 1982
Mary Pangborn Award for Research, New York State Department of Health, 1997
Select Recent Publications
Weber S, Weiser B, Burger H, Ramirez C, Kemal K, Korn K, Anastos K, Kaul R, Kovacs C, Doerfler W. Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpGs. Virology. 2014;449: 181-189.
Shi B, Kitchen C, Weiser B, Mayers D , Foley B, Kemal K, Anastos K, Suchard M, Parker M, Brunner C, Burger H. Evolution and recombination of genes encoding HIV-1 drug resistance and coreceptor usage during antiretroviral therapy. Virology. 2010;404:5-20.
Weiser B, Philpott S, Klimkait T, Burger H, Kitchen C, Burgisser P, Gorgievski M, Perrin L, Piffaretti J-C, Ledergerber B, and the Swiss HIV Cohort Study. HIV-1 coreceptor usage and CXCR4-specific viral load predict clinical disease progression during combination antiretroviral therapy. AIDS. 2008;22:469-79.
Fang G, Weiser B, Kuiken C, Philpott S, Rowland-Jones S, Plummer F, Kimani J, Shi B, Kaul R, Bwayo J, Anzala O, and Burger H. Recombination following superinfection by HIV-1. AIDS. 2004;18:153-159.
Kemal KS, Foley B, Burger H, Anastos K, Minkoff H, Kitchen C, Philpott S, Gao W, Robison E, Holman S, Dehner C, Beck S, Meyer W, Landay A, Kovacs A, Bremer J, Weiser B. HIV-1 in genital tract and plasma of women: compartmentalization of viral sequences, coreceptor usage, and glycosylation. Proc Natl Acad Sci USA. 2003;100:12972-12977.
Philpott S, Weiser B, Anastos K, Ramirez-Kitchen CM, Robison E, Meyer WA, Sacks HS, Mathur-Wagh U, Brunner C, and Burger H. Preferential suppression of CXCR4-specific strains of HIV-1 by antiviral therapy. J Clin Invest. 2001;107:431-438.
Fang, G, Weiser, B, Visosky A, Moran, T, Burger, H. PCR-mediated recombination: a general method applied to construct chimeric infectious molecular clones of plasma-derived HIV-1 RNA. Nature Med. 1999;5:239-242.
Fang, G., Burger, H., Grimson, R., Tropper, P., Nachman, S., Mayers, D., Weislow, O., Moore, R., Reyelt, C., Hutcheon, N., Baker, D., and Weiser, B. Maternal plasma human immunodeficiency virus type 1 RNA level: a determinant and projected threshold for mother-to-child transmission, Proc. Natl. Acad. Sci. USA 1995;92:12100-12104.
Burger, H., Weiser, B., Flaherty, K., Gulla, J., Nguyen, P., and Gibbs, R.A. Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts. Proc. Natl. Acad. Sci. USA 1991;88:11236-11240.
Weiser, B., Peress, N., Eilbott, D.J., La Neve, D., Seidman, R., and Burger, H. Human immunodeficiency virus type 1 expression in the central nervous system correlates directly with extent of disease. Proc. Natl. Acad. Sci. USA 1990;87:3997-4001.