Maryam Afkarian, M.D., Ph.D

Maryam Afkarian, M.D., Ph.D




  • Associate Professor


To see if Maryam Afkarian is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Lawrence J. Ellison Ambulatory Care Center

4860 Y St., Suite 0200
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Clinical Interests

Dr. Afkarian's clinical interests are in diabetic kidney disease.

Research/Academic Interests

Understanding molecular mechanisms of diabetic kidney disease.



Center/Program Affiliation

UC Davis Medical Group


M.D., Ph.D., Medicine/Immunology, Washington University School of Medicine, St. Louis MO 2003

M.M.Sc., Medical Sciences, Harvard School of Public Health, Boston MA 2010

B.A., UC Berkeley, Berkeley CA 1994

Internship: Internal Medicine, New York Presbyterian Hospital, New York NY 2003-2004


Internal Medicine, New York Presbyterian Hospital, New York NY 2004-2006


Nephrology, MGH-Brigham Joint Nephrology Fellowship, Boston MA 2006-2010

Board Certifications

American Board of Internal Medicine,

American Board of Internal Medicine, Nephrology,

Professional Memberships

American Society of Nephrologists

Honors and Awards

Scholars in Clinical Sciences Program Harvard Medical School, Boston, MA 2008-2010,

Select Recent Publications

Pichler R, Afkarian M, Dieter BP, Tuttle KR. Immunity and Inflammation in Diabetic Kidney Disease: Translating Mechanisms to Biomarkers and Treatment Targets. Am J Physiol Renal Physiol. 2016 Aug 24:ajprenal.00314.2016.

Afkarian M, Zelnick LR, Hall YN, Heagerty PJ, Tuttle K, Weiss NS, de Boer IH. Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014. JAMA. 2016 Aug 9;316(6):602-10.

Afkarian M, Katz R, Bansal N, Correa A, Kestenbaum B, Himmelfarb J, de Boer IH, Young B. Diabetes, Kidney Disease, and Cardiovascular Outcomes in the Jackson Heart Study. Clin J Am Soc Nephrol. 2016 Aug 8;11(8):1384-91.

Afkarian M, Zelnick LR, Ruzinski J, Kestenbaum B, Himmelfarb J, de Boer IH, Mehrotra R. Urine matrix metalloproteinase-7 and risk of kidney disease progression and mortality in type 2 diabetes. J Diabetes Complications. 2015 Nov-Dec;29(8):1024-31.

Afkarian M. Diabetic kidney disease in children and adolescents. Pediatr Nephrol. 2015 Jan;30(1):65-74; quiz 70-1.

de Boer IH, Afkarian M, Rue TC, Cleary PA, Lachin JM, Molitch ME, Steffes MW,  Sun W, Zinman B; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group.. Renal outcomes in patients with type 1 diabetes and macroalbuminuria. J Am Soc Nephrol. 2014 Oct;25(10):2342-50.

Afkarian M, Hirsch IB, Tuttle KR, Greenbaum C, Himmelfarb J, de Boer IH. Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. Physiol Rep. 2014 May 2;2(5):e12010.

Afkarian M, Sachs MC, Kestenbaum B, Hirsch IB, Tuttle KR, Himmelfarb J, de Boer IH. Kidney disease and increased mortality risk in type 2 diabetes. J Am Soc Nephrol. 2013 Feb;24(2):302-8.

Afkarian M, Bhasin M, Dillon ST, Guerrero MC, Nelson RG, Knowler WC, Thadhani R, Libermann TA. Optimizing a proteomics platform for urine biomarker discovery. Mol Cell Proteomics. 2010 Oct;9(10):2195-204.

Vrana M, Goodling A, Afkarian M, Prasad B. An Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS Proteomics. Drug Metab Dispos. 2016 Oct;44(10):1692-6.