Karen Reiser, M.D.

Karen Reiser, M.D.


Neurological Surgery


  • Research Biochemist


Clinical Interests

Dr. Reiser's research interests focus on nonlinear optical imaging and tissue engineering.


Neurological Surgery


M.D., UC Davis School of Medicine, Sacramento, California, 1974

B.A., Bryn Mawr College, Bryn Mawr, Pennsylvania, 1967

Professional Memberships

American Diabetes Association

American Federation for Clinical Research

American Occupational Medicine Association

American Thoracic Society

Gerontological Society of America

Honors and Awards

Lilly Prize for endocrine research, 1985

Joan Oettinger Memorial Award, 1984

Loren D. Carlson Award for best research by a senior medicine student, 1974

B.A., magna cum laude, with honors, 1967

Select Recent Publications

Tian J, Ishibashi K, Reiser K, Grebe R, Biswal S, Gehlbach P, Handa JT. Advanced glycation endproduct - induced aging of the retinal pigment epithelium and choroid: A comprehensive transcriptional response. Proc Natl Acad Sci, 102(33):11846-51, Aug 16, 2005. USA. Epub Aug 4, 2005. PMID: 16081535 [PubMed - In Process].

Wagner DR, Reiser KM, Lotz JC. Glycation increases human annulus fibrosus stiffness in both experimental measurements and theoretical predictions. J Biomech, 2005. (In Press - epub)

Ida H, Ishibashi K, Reiser K, Hjelmeland LM, Handa JT. Ultrastructural aging of the RPE-Bruch's membrane-choriocapillaris complex in the D-galactose-treated mouse. Invest Ophthalmol Vis Sci, 45(7):2348-54, Jul 2004. PMID: 15223816.

Reiser KM, Rocha-Mendoza I, Wang M, Yankelevich DR, Bratton C, Knoesen A, Lotz JC, Liebenman E. Polarization-modulated second-harmonic generation imaging: Method for quantitative assessment of disorganization in anulus. [Conference Paper] Conference Proceedings. 26th Annual International Conference of the Institute of Electrical and Electronics Engineers (IEEE) Engineering in Medicine and Biology Society (IEEE Cat. No. 04CH37558). IEEE, 7:4982-5, 2004. Piscataway, NJ, USA.

Reiser KM, Stoller P, Celliers P, Rubenchik A, Bratton C, Yankelevich D. Second harmonic generation in collagen. [Conference Paper] SPIE-Int. Soc. Opt. Eng. Proceedings of SPIE - the International Society for Optical Engineering, 5212(1):149-56, 2003. USA.

Stoller P, Celliers PM, Reiser KM, Rubenchik AM. Quantitative second-harmonic generation microscopy in collagen. Appl Opt, 42(25):5209-19, 2003.

Stoller P, Kim BM, Rubenchik AM, Reiser KM, Da Silva LB. Polarization-dependent optical second-harmonic imaging of a rat-tail tendon. J Biomed Opt, 7(2):205-14, 2002.

Stoller P, Reiser KM, Celliers PM, Rubenchik AM. Polarization-modulated second-harmonic generation in collagen. Biophys J, 82(6):3330-42, 2002.

Ido Y, Chang KC, Lejeune WS, Bjercke RJ, Reiser KM, Williamson JR, Tilton RG. Vascular dysfunction induced by AGE is mediated by VEGF via mechanisms involving reactive oxygen species, guanylate cyclase and protein kinase. C Microcirculation, 8(4):251-63, 2001.

Mullick AE, Walsh BA, Reiser KM, Rutledge JC. Chronic estradiol treatment attenuates stiffening, glycoxidation and permeability in rat carotid arteries. Am J Physiol Heart Circ Physiol, 281(5):H2204-10, 2001.