Biochemistry and Molecular Medicine (SOM)
UC Davis Medical Center Research I Room 3002
(916) 734-3656

Ph.D. - Harvard University - Cell and Developmental Biology - 1993
BS - National Taiwan University - 1986

Research interests

Cell-cell and cell-matrix junctions, focal adhesions, cytoskeleton, signal transduction, tensin, animal models for human diseases.

Graduate group affiliations

  • Biochemistry, Molecular, Cellular and Developmental Biology 
  • Pharmacology and Toxicology
  • Comparative Pathology

Recent publications


  • Lo, S. H.
    Focal adhesions: What's new inside
    Biol. 2006, 294:280-91
  • You, Z., Shi, X. B., DuRaine, G., Haudenschild, D., Tepper, C. G., Lo, S. H., Gandour-Edwards, R., deVere While, R., Reddi, A. H.
    Interleukin-17 receptor-like gene is a novel anti-apoptotic gene highly expressed in androgen independent prostate cancer
    Cancer Res. 2006, 66:175-183
  • Cui, Y., Liao, Y. C., and Lo, S. H.
    Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3
    Molecular Cancer Research 2004 Apr;2(4):225-32.
  • Lo, S.H.
    Molecules in focus: Tensin.
    Int. J. Biochem. Cell Biol. 2003
  • Chen H, Lo SH.
    Regulation of tensin-promoted cell migration by its focal adhesion binding and Src homology domain 2.
    Biochem J. 2003 Mar 15;370(Pt 3):1039-45.
  • Lo SH, Lo TB.
    Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer.
    Cancer Res. 2002 Aug 1;62(15):4217-21.
  • Vinall RL, Lo SH, Reddi AH.
    Regulation of articular chondrocyte phenotype by bone morphogenetic protein 7, interleukin 1, and cellular context is dependent on the cytoskeleton.
    Exp Cell Res. 2002 Jan 1;272(1):32-44.
  • Ishii A, Lo SH.
    A role of tensin in skeletal-muscle regeneration.
    Biochem J. 2001 Jun 15;356(Pt 3):737-45.
  • Tikoo A, Cutler H, Lo SH, Chen LB, Maruta H.
    Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445.
    Cancer J Sci Am. 1999 Sep-Oct;5(5):293-300.