Publications
2024
Lieng MK, Emami-Naeini P, Lee SC, Alber S, Yiu G. Teleophthalmology provides earlier eye care access for patients with newly-diagnosed diabetes. Heliyon. 2024 Feb 10;10(4):e25845. doi: 10.1016/j.heliyon.2024.e25845.
2023
Sazhnyev Y, Sin TN, Ma A, Chang E, Huynh L, Roszak K, Park S, Choy K, Farsiu S, Moshiri A, Thomasy SM, Yiu G. Choroidal Changes in Rhesus Macaques in Aging and Age-Related Drusen. Invest Ophthalmol Vis Sci. 2023 Sep 1;64(12):44. doi: 10.1167/iovs.64.12.44.
Lent-Schochet D, Avaylon J, Nguyen M, Hang A, Nava K, Lo T, Luu KY, Tran S, Emami-Naeini P, Moshiri A, Park S, Yiu G. OCT Predictors of Treatment Discontinuation in Eyes with RVO and ME. Ophthalmol Retina. 2023 May;7(5):462-464. doi: 10.1016/j.oret.2022.12.011.
Yiu G, Huang D, Wang Y, Wang Z, Yang M, Haskova Z. Predictors of As-Needed Ranibizumab Injection Frequency in Patients with Macular Edema Following Retinal Vein Occlusion. Am J Ophthalmol. 2023 May;249:74-81. doi: 10.1016/j.ajo.2023.01.004.
Sin T, Kim S, Li Y, Wang J, Chen R, Chung SH, Kim S, Casanova I, Park S, Smit-McBride Z, Sun N, Pomerantz O, Roberts JA, Guan B, Hufnagel RB, Moshiri A, Thomasy SM, Sieving PA, Yiu G. A spontaneous nonhuman primate model of myopic foveoschisis. Invest Ophthalmol Vis Sci. 2023 Jan 3;64(1):18. doi: 10.1167/iovs.64.1.18.
2022
Chung SH, Sin TN, Dang B, Ngo T, Lo T, Lent-Schochet D, Meleppat RK, Zawadzki RJ, Yiu G. CRISPR-based VEGF suppression using paired guide RNAs for treatment of choroidal neovascularization. Mol Ther Nucleic Acids. 2022 Apr 27;28:613-622. doi: 10.1016/j.omtn.2022.04.015.
Lee SC, Lieng MK, Alber S, Mehta N, Emami-Naeini P, Yiu G. Trends in Remote Retinal Imaging Utilization and Payments in the United States. Ophthalmology. 2022 Mar;129(3):354-357. doi: 10.1016/j.ophtha.2021.10.010.
Yellapragada B, Hornauer S, Snyder K, Yu S, Yiu G. Self-supervised feature learning and phenotyping for assessing age-related macular degeneration using retinal fundus images. Ophthalmol Retina. 2022Feb;6(2):116-129. doi: 10.1016/j.oret.2021.06.010.
2021
Mehta N, Robbins DA, Yiu G. Ocular Inflammation and Treatment Emergent Adverse Events in Retinal Gene Therapy. Int Ophthalmol Clin. 2021 Jul 1;61(3):151-177. doi: 10.1097/IIO.0000000000000366
Chung SH, Mollhoff IN, Mishra A, Sin TN, Ngo T, Ciulla T, Sieving P, Thomasy SM, Yiu G. Host immune responses after suprachoroidal delivery of AAV8 in nonhuman primate eyes. Hum Gene Ther. 2021 Jul;32(13-14):682-693.. doi: 10.1089/hum.2020.281.
Lent-Schochet D, Lo T, Luu KY, Tran S, Wilson MD, Moshiri A, Park SS, Yiu G. Natural History and Predictors of Vision Loss in Eyes with Diabetic Macular Edema and Good Initial Visual Acuity. Retina. 2021 Oct 1;41(10):2132-2139. doi: 10.1097/IAE.0000000000003167.
Mukkamala LK, Avaylon J, Welch RJ, Yazdanyar A, Emami-Naeini P, Wong S, Storkersen J, Loo J, Cunefare D, Farsiu S, Moshiri A, Park SS, Yiu G. Intraoperative Retinal Changes May Predict Surgical Outcomes After Epiretinal Membrane Peeling. Transl Vis Sci Technol. 2021 Feb 5:10(2):36, doi: 10.1167/tvst.10.2.36.
2020
Chung SH, Mollhoff IN, Nguyen U, Nguyen A, Stucka N, Tieu E, Manna S, Meleppat RK, Zhang P, Nguyen EL, Fong J, Zawadzki R, Yiu G. Factors Impacting Efficacy of AAV-Mediated CRISPR-Based Genome Editing for Treatment of Choroidal Neovascularization. Mol Ther Methods Clin Dev. 2020 Jun 12;17:409-417. doi: 10.1016/j.omtm.2020.01.006.
Yiu G, Chung SH, Mollhoff IN, Nguyen UT, Thomasy SM, Yoo J, Taraborelli D, Noronha G. Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. Mol Ther Methods Clin Dev. 2020 Mar 13;16:179-191. doi: 10.1016/j.omtm.2020.01.002.
Yiu G, Chung SH, Mollhoff IN, Wang Y, Nguyen UT, Shibata B, Cunefare D, Farsiu S, Roberts J, Thomasy SM. Long-term Evolution and Remodeling of Soft Drusen in Rhesus Macaques. Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):32. doi: 10.1167/iovs.61.2.32.
Lee SC, Tran S, Amin A, Morse LS, Moshiri A, Park SS, Yiu G. Retinal Vessel Density in Exudative and Nonexudative Age-Related Macular Degeneration on Optical Coherence Tomography Angiography. Am J Ophthalmol. 2020 Apr;212:7-16. doi: 10.1016/j.ajo.2019.11.031.
Yiu G, Welch RJ, Wang Y, Wang Z, Wang PW, Haskova Z. Spectral-Domain OCT Predictors of Visual Outcomes after Ranibizumab Treatment for Macular Edema Resulting from Retinal Vein Occlusion. Ophthalmol Retina. 2020 Jan;4(1):67-76. doi: 10.1016/j.oret.2019.08.009.
2019
Yiu G, Vuong VS, Tran S, Migacz J, Cunefare D, Farsiu S, Khandelwal N, Agrawal R, Cheung CMG. Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. Sci Rep. 2019 Mar 25;9(1):5049. doi: 10.1038/s41598-019-41509-2.
Moshiri A, Chen R, Kim S, Harris RA, Li Y, Raveendran M, Davis S, Liang Q, Pomerantz O, Wang J, Garzel L, Cameron A, Yiu G, Stout JT, Huang Y, Murphy CJ, Roberts J, Gopalakrishna KN, Boyd K, Artemyev NO, Rogers J, Thomasy SM. A nonhuman primate model of inherited retinal disease. J Clin Invest. 2019 Feb 1;129(2):863-874. doi: 10.1172/JCI123980.
2018
Smit-McBride Z, Nguyen J, Elliott GW, Wang Z, McBride RA, Nguyen AT, Oltjen SL, Yiu G, Thomasy SM, Pinkerton KE, Lee ES, Cunefare D, Farsiu S, Morse LS. Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. Mol Vis. 2018;24:633-646.
Snyder K, Yazdanyar A, Mahajan A, Yiu G. Association Between the Cilioretinal Artery and Choroidal Neovascularization in Age-Related Macular Degeneration: A Secondary Analysis From the Age-Related Eye Disease Study. JAMA Ophthalmol. 2018 Sep 1;136(9):1008-1014. doi: 10.1001/jamaophthalmol.2018.2650.
Yiu G, Wang Z, Munevar C, Tieu E, Shibata B, Wong B, Cunefare D, Farsiu S, Roberts J, Thomasy SM. Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections. Exp Eye Res. 2018 Mar;168:69-76. doi: 10.1016/j.exer.2018.01.012.
Willoughby AS, Vuong VS, Cunefare D, Farsiu S, Noronha G, Danis RP, Yiu G. Choroidal Changes After Suprachoroidal Injection of Triamcinolone Acetonide in Eyes With Macular Edema Secondary to Retinal Vein Occlusion. Am J Ophthalmol. 2018 Feb;186:144-151. doi: 10.1016/j.ajo.2017.11.020.
Yiu G. Genome Editing in Retinal Diseases using CRISPR Technology. Ophthalmol Retina. 2018 Jan;2(1):1-3. doi: 10.1016/j.oret.2017.09.015.
2017
Yiu G, Tieu E, Munevar C, Wong B, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy SM. In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. Sci Rep. 2017 Nov 3;7(1):15013. doi: 10.1038/s41598-017-14715-z.
Wong SS, Vuong VS, Cunefare D, Farsiu S, Moshiri A, Yiu G. Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography. Am J Ophthalmol. 2017 Oct 14. pii: S0002-9394(17)30428-2. doi: 10.1016/j.ajo.2017.10.005.
Sleiman K, Veerappan M, Winter KP, McCall MN, Yiu G, Farsiu S, Chew EY, Clemons T, Toth CA. Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration. Ophthalmology. 2017 Dec;124(12):1764-1777. doi: 10.1016/j.ophtha.2017.06.032.
2016
Yiu G, Vuong VS, Oltjen S, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy S. Effect of Uveal Melanocytes on Choroidal Morphology in Rhesus Macaques and Humans on Enhanced-Depth Imaging Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5764-5771. doi: 10.1167/iovs.16-20070.
Yiu G, Tieu EV, Nguyen AT, Wong B, Smit-McBride Z. Genomic Disruption of VEGF-A Expression in Human Retinal Pigment Epithelial Cells using CRISPR-Cas9 Endonuclease. Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5490-5497. doi: 10.1167/iovs.16-20296.
Vuong VS, Moisseiev E, Cunefare D, Farsiu S, Moshiri A, Yiu G. Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging OCT using Different Posterior Boundaries. Am J Ophthalmol. 2016 Sep; 169:104-12. doi: 10.1016/j.ajo.2016.06.023.
2015
Yiu G, Chiu SJ, Petrou PA, Stinnett S, Sarin N, Farsiu S, Chew EY, Wong WT, Toth CA. Relationship of Central Choroidal Thickness with Age-Related Macular Degeneration Status. Am J Ophthalmol. 2015 Apr;159(4):617-626. doi: 10.1016/j.ajo.2014.12.010.
2014
Yiu G, Manjunath V, Chiu SJ, Farsiu S, Mahmoud TH. Effect of Anti-Vascular Endothelial Grown Factor Therapy on Choroidal Thickness in Diabetic Macular Edema. Am J Ophthalmol. 2014 Oct; 158:745-751. doi: 10.1016/j.ajo.2014.06.006.
Yiu G, Pecen P, Sarin N, Chiu SJ, Farsiu S, Mruthyunjaya P, Toth CA. Characterization of the Choroid-Scleral Junction and Suprachoroidal Layer in Healthy Individuals on Enhanced-Depth Imaging Optical Coherence Tomography. JAMA Ophthalmol. 2014 Feb 1;132(2):174-81. doi: 10.1001/jamaophthalmol.2013.7288.