Publications
2020
Chung SH, Mollhoff IN, Nguyen U, Nguyen A, Stucka N, Tieu E, Manna S, Meleppat RK, Zhang P, Nguyen EL, Fong J, Zawadzki R, Yiu G. Factors Impacting Efficacy of AAV-Mediated CRISPR-Based Genome Editing for Treatment of Choroidal Neovascularization. Mol Ther Methods Clin Dev. 2020 Jun 12;17:409-417. doi: 10.1016/j.omtm.2020.01.006.
Yiu G, Chung SH, Mollhoff IN, Nguyen UT, Thomasy SM, Yoo J, Taraborelli D, Noronha G. Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. Mol Ther Methods Clin Dev. 2020 Mar 13;16:179-191. doi: 10.1016/j.omtm.2020.01.002.
Yiu G, Chung SH, Mollhoff IN, Wang Y, Nguyen UT, Shibata B, Cunefare D, Farsiu S, Roberts J, Thomasy SM. Long-term Evolution and Remodeling of Soft Drusen in Rhesus Macaques. Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):32. doi: 10.1167/iovs.61.2.32.
Lee SC, Tran S, Amin A, Morse LS, Moshiri A, Park SS, Yiu G. Retinal Vessel Density in Exudative and Nonexudative Age-Related Macular Degeneration on Optical Coherence Tomography Angiography. Am J Ophthalmol. 2020 Apr;212:7-16. doi: 10.1016/j.ajo.2019.11.031.
Yiu G, Welch RJ, Wang Y, Wang Z, Wang PW, Haskova Z. Spectral-Domain OCT Predictors of Visual Outcomes after Ranibizumab Treatment for Macular Edema Resulting from Retinal Vein Occlusion. Ophthalmol Retina. 2020 Jan;4(1):67-76. doi: 10.1016/j.oret.2019.08.009.
2019
Yiu G, Vuong VS, Tran S, Migacz J, Cunefare D, Farsiu S, Khandelwal N, Agrawal R, Cheung CMG. Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. Sci Rep. 2019 Mar 25;9(1):5049. doi: 10.1038/s41598-019-41509-2.
Moshiri A, Chen R, Kim S, Harris RA, Li Y, Raveendran M, Davis S, Liang Q, Pomerantz O, Wang J, Garzel L, Cameron A, Yiu G, Stout JT, Huang Y, Murphy CJ, Roberts J, Gopalakrishna KN, Boyd K, Artemyev NO, Rogers J, Thomasy SM. A nonhuman primate model of inherited retinal disease. J Clin Invest. 2019 Feb 1;129(2):863-874. doi: 10.1172/JCI123980.
2018
Smit-McBride Z, Nguyen J, Elliott GW, Wang Z, McBride RA, Nguyen AT, Oltjen SL, Yiu G, Thomasy SM, Pinkerton KE, Lee ES, Cunefare D, Farsiu S, Morse LS. Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. Mol Vis. 2018;24:633-646.
Snyder K, Yazdanyar A, Mahajan A, Yiu G. Association Between the Cilioretinal Artery and Choroidal Neovascularization in Age-Related Macular Degeneration: A Secondary Analysis From the Age-Related Eye Disease Study. JAMA Ophthalmol. 2018 Sep 1;136(9):1008-1014. doi: 10.1001/jamaophthalmol.2018.2650.
Yiu G, Wang Z, Munevar C, Tieu E, Shibata B, Wong B, Cunefare D, Farsiu S, Roberts J, Thomasy SM. Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections. Exp Eye Res. 2018 Mar;168:69-76. doi: 10.1016/j.exer.2018.01.012.
Willoughby AS, Vuong VS, Cunefare D, Farsiu S, Noronha G, Danis RP, Yiu G. Choroidal Changes After Suprachoroidal Injection of Triamcinolone Acetonide in Eyes With Macular Edema Secondary to Retinal Vein Occlusion. Am J Ophthalmol. 2018 Feb;186:144-151. doi: 10.1016/j.ajo.2017.11.020.
Yiu G. Genome Editing in Retinal Diseases using CRISPR Technology. Ophthalmol Retina. 2018 Jan;2(1):1-3. doi: 10.1016/j.oret.2017.09.015.
2017
Yiu G, Tieu E, Munevar C, Wong B, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy SM. In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. Sci Rep. 2017 Nov 3;7(1):15013. doi: 10.1038/s41598-017-14715-z.
Wong SS, Vuong VS, Cunefare D, Farsiu S, Moshiri A, Yiu G. Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography. Am J Ophthalmol. 2017 Oct 14. pii: S0002-9394(17)30428-2. doi: 10.1016/j.ajo.2017.10.005.
Sleiman K, Veerappan M, Winter KP, McCall MN, Yiu G, Farsiu S, Chew EY, Clemons T, Toth CA. Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration. Ophthalmology. 2017 Dec;124(12):1764-1777. doi: 10.1016/j.ophtha.2017.06.032.
2016
Yiu G, Vuong VS, Oltjen S, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy S. Effect of Uveal Melanocytes on Choroidal Morphology in Rhesus Macaques and Humans on Enhanced-Depth Imaging Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5764-5771. doi: 10.1167/iovs.16-20070.
Yiu G, Tieu EV, Nguyen AT, Wong B, Smit-McBride Z. Genomic Disruption of VEGF-A Expression in Human Retinal Pigment Epithelial Cells using CRISPR-Cas9 Endonuclease. Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5490-5497. doi: 10.1167/iovs.16-20296.
Vuong VS, Moisseiev E, Cunefare D, Farsiu S, Moshiri A, Yiu G. Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging OCT using Different Posterior Boundaries. Am J Ophthalmol. 2016 Sep; 169:104-12. doi: 10.1016/j.ajo.2016.06.023.
2015
Yiu G, Chiu SJ, Petrou PA, Stinnett S, Sarin N, Farsiu S, Chew EY, Wong WT, Toth CA. Relationship of Central Choroidal Thickness with Age-Related Macular Degeneration Status. Am J Ophthalmol. 2015 Apr;159(4):617-626. doi: 10.1016/j.ajo.2014.12.010.
2014
Yiu G, Manjunath V, Chiu SJ, Farsiu S, Mahmoud TH. Effect of Anti-Vascular Endothelial Grown Factor Therapy on Choroidal Thickness in Diabetic Macular Edema. Am J Ophthalmol. 2014 Oct; 158:745-751. doi: 10.1016/j.ajo.2014.06.006.
Yiu G, Pecen P, Sarin N, Chiu SJ, Farsiu S, Mruthyunjaya P, Toth CA. Characterization of the Choroid-Scleral Junction and Suprachoroidal Layer in Healthy Individuals on Enhanced-Depth Imaging Optical Coherence Tomography. JAMA Ophthalmol. 2014 Feb 1;132(2):174-81. doi: 10.1001/jamaophthalmol.2013.7288.