Dr. Maddock is a psychiatrist with special expertise in Anxiety Disorders, Psychopharmacology and Cognitive Behavioral Therapy.
Dr. Maddock's research focuses on understanding the brain bases of psychiatric disorders, primarily through the use of MRI and MR Spectroscopy techniques to investigate brain metabolism and function.
He studies a range of disorders, including anxiety, psychotic and mood disorders. He also studies how health-promoting activities such as exercise, sleep, and meditation affect the brain in healthy individuals.
M.D., UC Davis School of Medicine, Sacramento CA 1982
B.A., UC Davis, Davis CA 1970
M.S., Physiology, UC Davis, Davis CA 1975
Internship: Psychiatry, Stanford University, Stanford CA 1982-1983
Psychiatry, Stanford University, Stanford CA 1983-1986
Psychiatric Research, Stanford University, Stanford CA 1985-1986
American Board of Psychiatry and Neurology, 1989
Select Recent Publications
Yoon JH, Grandelis A, Maddock RJ. Dorsolateral prefrontal cortex GABA concentration in humans predicts working memory load processing capacity. Journal of Neuroscience. 2017;36(46):11788-11794.
Maddock RJ, Casazza GA, Fernandez DH, and Maddock MI. Acute Modulation of Cortical Glutamate and GABA Content by Physical Activity. Journal of Neuroscience. 2016; 36(8):2449-57.
Buonocore MH, Maddock RJ. Magnetic resonance spectroscopy of the brain: A review of physical principles and technical methods. Reviews in the Neurosciences. 2015;26(6):609-32.
Maddock RJ, Buonocore MH, Miller AR, Yoon JH, Soosman SK, Unruh AM. Abnormal activity-dependent brain lactate and glutamate+glutamine responses in panic disorder. Biological Psychiatry. 2013; 73:1111-1119.
Maddock RJ, Buonocore MH. MR spectroscopic studies of the brain in psychiatric disorders. Current Topics in Behavioral Neuroscience. 2012;11:199-251.
Maddock RJ. The lactic acid response to alkalosis in panic disorder: An integrative review. Journal of Neuropsychiatry and Clinical Neurosciences. 2001;13: 22-34.
Maddock, RJ. Retrosplenial cortex and emotion: New insights from functional imaging studies of the human brain. Trends in Neurosciences. 1999;22:310-316.
To view a detailed list of Dr. Maddock's publications, please click here.
Maddock RJ, Casazza GA, Buonocore MH, Tanase C. Vigorous exercise increases brain lactate and Glx (glutamateglutamine): a dynamic 1H-MRS study. Neuroimage. 2011 Aug 15;57(4):1324-30. Epub 2011 May 27.
Yoon JH, Maddock RJ, Rokem A, Silver MA, Minzenberg MJ, Ragland JD, Carter CS. GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression. J Neurosci. 2010 Mar 10;30(10):3777-81.
Maddock, R.J., Buonocore, M.H., Copeland, L.E., Richards, A.L. Elevated brain lactate responses to neural activation in panic disorder: A dynamic 1H-MRS study. Molecular Psychiatry. 2009;14:537-545.