Junior Specialist: Computational Specialist in Cardiovascular Physiology

The Department of Physiology and Membrane Biology has a Junior Specialist position available in Dr. Clancy’s lab. See more details below.

Junior Specialist in Cardiovascular Physiology

For more information and to apply: https://recruit.ucdavis.edu/JPF06332

Recruitment Period

Open Date: February 16, 2024

Initial Review Date: March 1, 2024 - Apply by March 1, 2024 (11.59 p.m.) to be considered in the first round of applicants. All applicants received will be released to the Search Committee the following day. More review dates will be added if the position is not filled from the first pool of applicants.

Final Date: June 30, 2024 - Applications will continue to be accepted through this date, but those received after the initial review date will only be considered if the position has not yet been filled.

Postdoctoral Researcher Position

Dr. Daniah Beleford’s lab, within the Department of Physiology and Membrane Biology and the Department of Pediatrics at the University of California Davis, is recruiting for a postdoctoral scholar to participate in both basic and translational vascular biology research. Successful candidates will enjoy a supportive, diverse, and stimulating laboratory and departmental environment, filled with lots of collaboration, cutting-edge instrumentation and facilities, and a strong culture of training and mentorship.

The Beleford Lab studies underlying changes in molecular signaling that cause vascular malformations (abnormal development of blood vessels) in Hereditary Hemorrhagic Telangiectasia and other genetic vascular conditions. Hereditary Hemorrhagic Telangiectasia (HHT) is a rare Mendelian vascular condition that is characterized by arteriovenous malformations (AVMs), direct connections between arteries and veins without intervening capillary beds. It has previously been shown that single nucleotide polymorphisms within the genetic modifier PTPN14 (protein tyrosine phosphatase, nonreceptor, 14) associate with pulmonary AVMs in two large HHT cohorts. Our preliminary data suggest that the PTPN14 gene product binds and stabilizes BMP9 signaling components in endothelial cells, inhibiting ubiquitin-mediated protein turnover and promoting vascular stability. The Beleford Lab seeks to clarify the molecular interplay between PTPN14 and BMP9, TGFβ, and HIPPO signaling pathway components with the goal of understanding what causes the loss of vascular integrity in HHT and other severe vascular conditions in order to ultimately tailor targeted therapeutic interventions. Competitive applicants will be skilled in basic molecular and cell biology laboratory techniques as well as in mouse handling, crosses and care. The lab uses techniques such as DNA and protein electrophoresis, PCR, immunohisto- and cytochemistry, co-immunoprecipitation, proximity ligation assay.

Work/life Balance

UC Davis is a supportive, diverse, and collaborative community, ideally situated in the sunny Sacramento Valley between beautiful Lake Tahoe for winter skiing and summer beaches, and the San Francisco Bay Area.

Qualifications

Applicants must have a Ph.D. and/or M.D., D.O., M.B.B.S. degree and should have a demonstrated background in basic molecular and cell biology techniques as above. Additional training in basic genetics and genomics, including in the interpretation of genetic sequencing data, is helpful.

Successful applicants will be expected to stay abreast of current literature in the field, design and execute experiments, assist in the collection of data for grant applications, and to prepare their results for presentation at national and international scientific conferences and for publication in peer-reviewed journals. Successful applicants will also be expected to mentor graduate and undergraduate students, including hands-on teaching at the bench and in the vivarium. The ability to work independently with minimal supervision is also crucial.

Salary

The posted UC salary scales set the minimum pay determined by rank and/or step at appointment. See Table 23: Postdoctoral Scholar-Employee, Postdoctoral Scholar-Fellow, Postdoctoral Scholar-Paid Direct, Fiscal Year. The salary range for this position is $64,480 – $69,342. “Off-scale salaries”, i.e., a salary that is higher than the published system-wide salary at the designated rank and step, are offered when necessary to meet competitive conditions, qualifications, and experience.

To Apply

Qualified candidates should email the following items to Dr. Daniah Beleford at dbeleford@ucdavis.edu.

  • CV/Biosketch
  • Cover letter expressing your interest in the position
  • Minimum of 3 professional references (Name and Email Address)