National Institutes of Health (NIH) - funded postdoctoral position in host-virus interactions

 

Location

University of California, Davis, Department of Medical Microbiology and Immunology

 

Closing Date

Applications will be reviewed starting February 1, 2019, and will continue to be accepted until a suitable candidate is selected.

 

Description

The Rothenburg laboratory in the Department of Medical Microbiology and Immunology at the University of California, Davis is recruiting a Postdoctoral Scholar (Principal Investigator: Greg Brennan). The lab uses an interdisciplinary approach to examine host-virus interactions and mechanisms of viral evolution that may promote cross-species transmission. The main responsibilities of the postdoc will include working on an exciting study currently underway examining the impact of adaptive mutations in the viral polymerase on viral transcription and translation, and defining novel adaptive mutations that permit viral replication in otherwise resistant cells (Brennan, et al., PLoS Pathogens, 2014; Brennan, et al., Journal of Virology, 2015). Experience with genomic, proteomic, and/or bioinformatic methodologies is desirable but not necessary. This position is guaranteed for 1 year, and there is the possibility for renewal dependent on performance. The successful candidate will also have career development opportunities including mentoring graduate students, reviewing journal articles, presenting at seminars and meetings, and applying for postdoctoral fellowships.

 

Qualifications

  • Ph.D. in Virology, Evolutionary Biology, or a related field
  • A strong publication record demonstrating prior experience with molecular biology, cutting-edge sequencing technologies, or proteomics
  • Excellent writing and communication skills
  • Ability to work independently and to work as part of a team
  • Excellent organizational skills

 

How to apply

Please submit a cover letter summarizing your past experience and research interests and Curriculum Vitae including the names and contact information of 3 references via email to gbrennan@ucdavis.edu.

The University of California (UC), Davis, School of Medicine, department of Medical Microbiology and Immunology seeks to hire a full-time employee as an Assistant Project Scientist.

This position requires creative contributions to and collaborative development of an active research program investigating topics relevant to the research area of host-virus interactions and evolution of those interactions, by studying viruses such as lentiviruses, cytomegaloviruses, and adenoviruses as well as animal models for both lentivirus and cytomegalovirus infections.

 

Basic requirements

PhD in the fields related to veterinary sciences, immunology, or virology. 4-5 years of research experience in working with human immunodeficiency virus, simian immunodeficiency virus, rhesus cytomegalovirus, regulatory T cells, and host-virus interactions. The candidate should have extensive experience in tissue culture work, flow cytometry, functional assays for T cell function, cell lines transduced with cloned TCRs, virus infection of primary and established cell lines, and titration of viruses using plaque assays. Excellent publication record and communication skills are required.

 

Preferred requirements

Experience in studying regulatory T cells in HIV-infected humans, regulatory T cells in SIV-infected macaques, and conducting pathogenesis studies in non-human primates are highly preferred. Strong experience of studying and manipulating innate immune cell receptors is highly preferred.

 

Responsibilities include, but are not limited to, developing strategies to test new hypotheses using cell culture models of infection and in vivo models of pathogenesis, primate immunology, as well as molecular biology approaches. The candidate is expected to design specific projects, including the selection of appropriate techniques, supervise students or technicians regarding the technical aspects of the research (i.e.: trouble-shooting problems, interpreting results and planning follow-up experiments), design and conduct a series of experiments to evaluate the contributions of immune cells to protection against disease, publish research in peer-reviewed journals either independently or in collaboration with the PI, or other members of the research team, assist in writing proposals for funding from federal and state agencies and other funding organizations, prepare and assist in the preparation of reports as required by granting agencies and prepare modifications of budgets and other grant components as needed, participate in professional societies and conferences appropriate to his/her research field and will serve as a reviewer of research proposals and scientific publications as appropriate, attend seminars to present research results and may give oral presentations to public and professional interest groups. When appropriate, the candidate may coordinate and/or give presentations at seminars, laboratory meetings or educational functions, engage in public outreach activities that include presenting scientific research results to the general public and providing relevant advice to individuals and public agencies and engage in University service activities such as guest lecturing and committee service. Teaching classroom courses is not an expectation of this position.

Qualified applicants should upload a Cover Letter, CV and names and contact information of three references online at https://recruit.ucdavis.edu/apply/JPF02624. For full consideration, applications should be received by February 13, 2019. However, this position will remain open until filled through June 30, 2019.

The University of California, Davis is an affirmative action/equal opportunity employer with a strong institutional commitment to the achievement of diversity among its faculty, staff and students.

UC Davis commits to inclusion excellence by advancing equity, diversity and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct.

If you need accommodation due to a disability, please contact the recruiting department.

Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify.

UC Davis is a smoke & tobacco-free campus (http://breathefree.ucdavis.edu/).