Online Video Resources

The goal of this curriculum is to provide a broad and current introduction to important aspects of dementias and dementia related research. The target audience is junior investigators. Dementia research is highly diverse in content, ranging from basic biophysical research to social science and implementation science research. Investigators entering dementia research come from very diverse disciplinary backgrounds and those completing initial training such doctoral work or fellowships usually have strong knowledge of their discipline and good knowledge of closely allied fields. Conventional training, however, doesn’t provide education about many aspects of dementia and dementia research that are important in understanding critical issues in the field. This curriculum is aimed at providing a relatively sophisticated introduction to critical aspects of dementias across the broad sweep of the field. The ultimate goal is to enhance the ability of junior investigators to read and understand relevant literature outside their own disciplines.

Module 2: Dementia Pathology & Pathogenesis
This module includes an overview of the defining histopathologic features of dementias, plus presentations on the biologies of the proteinopathies thought to be central to most dementias. The heterogeneous vascular dementias are also discussed.

Module 3: Dementia Genetics
Genetic forms of dementias provide major insights into the biology of dementias. This module covers the genetics of Alzheimer disease and the Frontotemporal dementias. The approach to genetics in clinical practice and their social impacts are discussed.

Module 4: Dementia Imaging
Imaging methods are critical tools for a wide variety of dementia research. This module covers basics of MRI methods, as well as applications of MRI and PET in dementia research.

Module 5: Therapy Development in Dementias
The development of effective therapies is the major goal of dementia research. This module covers present pharmacologic approaches, the nature of the drug development process, the role of biomarkers, and possible non-pharmacologic interventions.

Module 6: Health Services & Policy Dementia
This module covers the basics of dementia epidemiology and economic impacts.

Module 7: Research Performance in Ethnically
Dementia research must reach and reflect the increasing diversity of the American population. This poses a challenge for much clinical research. The presentations in the module discuss recruitment and evaluation of ethnically diverse populations