Assistant/Associate Project Scientist - Chen Lab

Position Overview

Salary Range: A reasonable estimate for this position is $74,100 - $94,200

Application Window

Open Date: June 28, 2024

Next Review Date: Monday, July 15, 2024 at 11:59 p.m. (Pacific Time)
Apply by this date to ensure full consideration by the committee.

Final Date: Saturday, August 31, 2024 at 11:59 p.m. (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position Description

The Department of Biochemistry and Molecular Medicine at the University of California Davis, School of Medicine is recruiting for a full-time Project Scientist at the Assistant or Associate rank in cancer epigenetics and therapeutics.

The Project Scientist makes significant and creative contributions to a research or creative project in his/her academic discipline. The appointee possesses the subject matter expertise and the creative energy necessary to function at a high level of competence. The appointee will participate in activities to increase, improve, or upgrade competency in field. Appointees with Project Scientist series may engage in University and public service. They do not have teaching responsibilities. Although the Project Scientist is expected to work independently under the general guidance of an academic member with an independent research program (i.e., Professor, Professional Researcher, etc.), they are not required to develop an independent research program or reputation. The Project Scientist will carry out research or creative programs with supervision by an individual in an academic title that carries with it automatic Principal status. The Project Scientist does not usually serve as a Principal Investigator but may do so by exception.

The incumbent will work under the supervision of Professor Hongwu Chen and the ability to work cooperatively and collegially in a diverse environment.

Major Responsibilities

1) RESEARCH (90% Effort)

Research Activity (80%)
This position requires creative contributions to and collaborative development of an active research program investigating topics relevant to the research area of identification and functional elucidation of key epigenetic regulators and nuclear receptors in prostate cancer. Topics include designing and performing experiments and bioinformatics analysis to identify specific members of the orphan nuclear receptors and epigenetic regulators as key drivers of prostate cancer progression and to elucidate the mechanisms of their function in the disease progression such as NEPC, and identification of therapeutics that can effectively target the regulators or receptors identified.

The appointee will also help to determine research goals in consultation with the Principal Investigators. The Project Scientist will design specific projects, including the selection of appropriate methods and techniques. In some cases, the appointee may supervise students or technicians regarding the technical aspects of the research, including methods development, trouble-shooting problems, interpreting results and planning follow-up experiments. The appointee collaborates with scientific colleagues in multi-disciplinary projects that include components falling within the appointee’s area of expertise.

Publication (5%)
The appointee will publish research in peer-reviewed journals either independently or in collaboration with the PI or other members of the research team.

Grant Acquisition (5%)
The appointee will assist in writing proposals for funding from federal and state agencies and other funding organizations. The appointee will prepare and assist in the preparation of reports as required by granting agencies and prepare modifications of budgets and other grant components as needed.


The candidate will participate in professional societies and conferences appropriate to his/her specific fields of cancer epigenetics and therapeutics and will serve as a reviewer of research proposals and scientific publications as appropriate. The candidate will attend seminars to present research results and may give oral presentations to public and professional interest groups. When appropriate, the candidate may coordinate and/or give presentations at seminars, laboratory meetings or educational functions.


  • The appointee may undertake administrative tasks relevant to the smooth running of the laboratory enterprise as appropriate.

This recruitment is conducted at the assistant/associate rank. The resulting hire will be at the assistant/associate rank, regardless of the proposed appointee's qualifications.


Basic Qualifications (required at time of application)

  • Ph.D. or equivalent degree in fields of cancer epigenetics and therapeutics.
  • At least 5 years of experience in the above fields post terminal degree.

Additional Qualifications (required at time of start)

  • Research experience in successfully performing all of the following functional epigenetics and genomics studies:
    ChIP-seq, scRNA-seq and ATAC-seq analyses with tissues (e.g. patient samples or their pre-clinical models such as patient-derived xenograft tumor tissues) and in successful bioinformatics analysis of the data generated by the above functional epigenomics and genomics experiments.
  • Evidence of academic accomplishment such as refereed journal papers and conference presentations
  • Experience in mechanistic studies of orphan nuclear receptors and epigenetic regulators in prostate cancer progression.


Document Requirements

  • Curriculum Vitae - Your most recently updated C.V.
  • Cover Letter
  • Statement of Research (Optional)
  • Statement of Teaching (Optional)
  • Statement of Contributions to Diversity, Equity, and Inclusion - Contributions to diversity, equity, and inclusion documented in the application file will be used to evaluate applicants. Visit for guidelines about writing a statement and why one is requested.

Reference Requirements

  • 3-5 required (contact information only)

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