Residency Program - Case of the Month
February 2015 - Presented by Dr. Nima Amini
The patient is a 30-year-old male with a history of Hodgkin lymphoma which was diagnosed 5 years ago. He received chemotherapy followed by an allogenic stem cell transplant in 2013. He subsequently developed poikiloderma, keratoconjunctivitis sicca, chronic diarrhea and lost 20% of his weight over a period of 4 months. His treatment involved apheresis methods to alleviate his symptoms. However, in December 2014, he developed cervical lymphadenopathy with continued weight loss. A lymph node biopsy revealed recurrent Hodgkin lymphoma.
Recently his weight has started to increase, and therefore chemotherapy is being held for now by the patient's oncology team.
- What was the condition he developed after allogenic stem cell transplant?
- What type of apheresis procedure is recommended to alleviate symptoms belonging to this condition?
- What is the mechanism of action in this procedure?
- What are the ASFA Category and ASFA Grading Recommendations?
What is the appropriate apheresis plan for this patient’s current status?