Resident Program - Case of the Month
September 2019 - Presented by Dr. Miao Tian (Mentored by Dr. Karen Matsukuma)
Clinical History
A 65-year-old man presented with one week of non-radiating right lower quadrant abdominal pain associated with nausea, vomiting, and anorexia. CT on admission showed acute non-perforated appendicitis. He was subsequently taken to the OR for laparoscopic appendectomy. Intraoperatively he was found to have perforated appendicitis with murky, purulent fluid throughout the abdomen.
Histology
Figure 1.
Figure 2.
Figure 3.
Figure 4. CDX2
Figure 5. Synaptophysin
D.) Low-grade appendiceal goblet cell adenocarcinoma
Low-grade appendiceal goblet cell adenocarcinoma (LG-GCAC) (formerly typical goblet cell carcinoid) is a mixed endocrine-exocrine neoplasm almost exclusively seen in the appendix.
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