Marike Zwienenberg, M.D., FAANS

Marike Zwienenberg, M.D., FAANS


Pediatric Neurological Surgery


Neurological Surgery


  • Health Sciences Associate Clinical Professor of Neurological Surgery


To see if Marike Zwienenberg is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

UC Davis Midtown Ambulatory Care Center

3160 Folsom Blvd, Suite 2100
Sacramento, CA 95816
Driving Directions

Primary Phone:

Additional Phone Numbers

Clinic Phone: 916-734-4300
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Philosophy of Care

Disorders affecting the brain and spine are often life-altering for patients and their families. When faced with disease affecting the central nervous system, selecting the optimal treatment strategy for a child can be difficult and complex. As a neurosurgeon I strive to educate and empower parents to make these challenging healthcare decisions so that they can best fulfill the needs of their child and family.

Clinical Interests

Dr. Zwienenberg is fellowship trained and board certified in pediatric neurological surgery. She provides medical and surgical care to patients with brain and spinal cord tumors, hydrocephalus, craniofacial disorders, epilepsy, spinal dysraphism (including fetal surgery), vascular anomalies and traumatic brain injury. 

Research/Academic Interests

Dr.Zwienenberg's research interests include studying the effects of injury to the developing brain and the long-term impact on neurological functioning. Her clinical research interests include the development of clinical guidelines and decision instruments to optimize the care of patients with traumatic brain injury. 


Neurological Surgery
Pediatric Surgery

Center/Program Affiliation

UC Davis Children's Hospital
Trauma Program


M.D., Erasmus University Rotterdam, Rotterdam, The Netherlands 1997

Internship: General Surgery, UC Davis Medical Center, Sacramento CA 2000-2001


Neurological Surgery, UC Davis Medical Center, Sacramento CA 2001-2006


Pediatric Neurological Surgery, St. Jude Children?s Research Hospital/Le Bonheur Children?s Medical Center, Memphis TN 2006-2007

Board Certifications

American Board of Neurological Surgery, 2012

American Board of Neurological Surgery - Pediatric Neurological Surgery - Diplomat, 2013

American Board of Pediatrics - Pediatric Neurological Surgery, 2013

Professional Memberships

American Association of Neurological Surgeons

American Society of Pediatric Neurosurgeons

Pediatric section of American Association of Neurological Surgeons

Honors and Awards

Dean?s Team Award for Excellence in Clinical Care, UC Davis School of Medicine, 2017

Outstanding leadership award, UC Davis Department of Neurological Surgery, 2016

Dean?s Team Award for Excellence in Clinical Care, UC Davis School of Medicine, 2014

Select Recent Publications

Ament JD, Greenan KN, Tertulien P, Galante JM, Nishijima DK, Zwienenberg M. Medical necessity of routine admission of children with mild traumatic brain injury to the intensive care unit. J Neurosurg Pediatr. 2017 Jun;19(6):668-674.

Nishijima DK, Yang Z, Urbich M, Holmes JF, Zwienenberg-Lee M, Melnikow J, Kuppermann N. Cost-effectiveness of the PECARN rules in children with minor head trauma. Ann Emerg Med. 2015 Jan;65(1):72-80.

Sarkar K, Keachie K, Nguyen U, Muizelaar JP, Zwienenberg-Lee M, Shahlaie K. Computed tomography characteristics in pediatric versus adult traumatic brain injury. J Neurosurg Pediatr. 2014 Mar;13(3):307-14.

mpey PE, Velez de Mendizabal N, Bell MJ, Bies RR, Anderson KB, Kochanek PM, Adelson PD, Poloyac SM; Pediatric TBI Consortium: Therapeutic hypothermia decreases phenytoin elimination in children with traumatic brain injury. Hypothermia Investigators. Crit Care Med. 2013 Oct; 41(10):2379-87.

Arocho-Quinones EV, Kolimas A, LaViolette PS, Kaufman BA, Foy AB, Zwienenberg M, Lew SM. Split laminotomy versus conventional laminotomy: postoperative outcomes in pediatric patients. J Neurosurg Pediatr. 2008;Mar 23:1-11.

Justice CM, Yagnik G, Kim Y, Peter I, Jabs EW, Erazo M, Ye X, Ainehsazan E, Shi L, Cunningham ML, Kimonis V, Roscioli T, Wall SA, Wilkie AO, Stoler J, Richtsmeier JT, Heuzé Y, Sanchez-Lara PA, Buckley MF, Druschel CM, Mills JL, Caggana M, Romitti PA, Kay DM, Senders C, Taub PJ, Klein OD, Boggan J, Zwienenberg-Lee M, Naydenov C, Kim J, Wilson AF, Boyadjiev SA. A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9. Nat Genet. 2012 Dec;44(12):1360-4.

Sanford RA, Merchant TE, Zwienenberg-Lee M, Kun LE and FA Boop. Advances in surgical techniques for resection of childhood cerebellopontine angle ependymomas are key to survival. Childs Nerv Syst. 2009;25: 1229-1240.

Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, Newell D, Verweij B, Bullock MR, Baker A, Coplin W, Mericle R, Dai J, Rocke D and JP Muizelaar. Balloon Prophylaxis for Aneurysmal Vasospasm (BPAV) Study Group. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke (Journal of the American Heart Association). 2008;39: 1759-1765.

Pang D, Tse HH, Zwienenberg-Lee M, Smith M and J Zovickian. The combined use of hydroxyapatite and bioresorbable plates to repair cranial defects in children. Journal of Neurosurgery (Pediatrics I). 2005;102: 35-43.

Zwienenberg M, Muizelaar JP. Severe pediatric head injury: the role of hyperemia revisited. J Neurotrauma. 1999 Oct;16(10):937-43.

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