Dr. Kale practices compassionate care, forming a relationship with the whole family and including them in treatment and care decisions. She believes in the collaborating with other specialties when taking care of complex patients.
Dr. Kale is well versed in the diagnosis and treatment of common and uncommon conditions affecting the kidneys and urinary tract in children, including children with kidney failure who require dialysis or transplantation. She has extensive experience in the treatment of pediatric kidney disorders and actively participates in the teaching mission of the department with lectures, small group discussions both at the bedside and under formal settings for medical students, residents and ancillary staff.
Dr. Kale is currently evaluating a new blood test which may give information about kidney transplant rejection that is usually diagnosed by a biopsy. With information from this study, we may be able to avoid biopsies at least in some patients.
Pediatric Nephrology and Kidney Transplantation
M.D., Gandhi Medical College, Hyderabad, India 1980
Pediatrics, University of Medicine and Dentistry/Robert Wood Johnson University Hospital, Newark NJ 1985-1988
Pediatric Nephrology, Baylor College of Medicine, Houston TX 1989-1992
Residents Teaching Award, 2020, 2021
Sacramento "Top Docs," 2019, 2020, 2021
Fullbright and Jaworski Faculty award for Excellence in Teaching and Evaluation, 2012
Haddad M, Kale A, Butani L. Intravenous cyclophosphamide induces remission in children with difficult to treat steroid resistant nephrotic syndrome from minimal change disease. BMC Nephrol. 2021;22:395. doi:10.1186/s12882-021-02605-6.
Bekheirnia MR, Bekheirnia N, Bainbridge MN, Gu S, Coban Akdemir ZH, Gambin T, Janzen NK, Jhangiani SN, Muzny DM, Michael M, Brewer ED, Elenberg E, Kale AS, Riley AA, Swartz SJ, Scott DA, Yang Y, Srivaths PR, Wenderfer SE, Bodurtha J, Applegate CD, Velinov M, Myers A, Borovik L, Craigen WJ, Hanchard NA, Rosenfeld JA, Lewis RA, Gonzales ET, Gibbs RA, Belmont JW, Roth DR, Eng C, Braun MC, Lupski JR, Lamb DJ. Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene. Genet Med. 2017 Apr;19(4):412-420. doi:10.1038/gim.2016.131. Epub 2016 Sep 22. PMID:27657687.
Michael M, Minard CG, Kale AS, Brewer ED. Outcomes of two-drug maintenance immunosuppression for pediatric renal transplantation: 10-yr follow-up in a single center. Pediatr Transplant. 2016 Feb;20(1):49-58. doi:10.1111/petr.12627. Epub 2015 Nov 2. PMID:26916966.
Riley AA, Munden MM, Kale AS, Cruz AT. Immune Reconstitution Inflammatory Syndrome Causing Hypertension in a Child Short Title: IRIS & hypertension in a child with TB. J Clin Pediatric Nephrol. 2015.
Gbadegesin RA, Adeyemo A, Webb NJ, Greenbaum LA, Abeyagunawardena A, Thalgahagoda S, Kale A, Gipson D, Srivastava T, Lin JJ, Chand D, Hunley TE, Brophy PD, Bagga A, Sinha A, Rheault MN, Ghali J, Nicholls K, Abraham E, Janjua HS, Omoloja A, Barletta GM, Cai Y, Milford DD, O'Brien C, Awan A, Belostotsky V, Smoyer WE, Homstad A, Hall G, Wu G, Nagaraj S, Wigfall D, Foreman J, Winn MP; Mid-West Pediatric Nephrology Consortium. HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome. J Am Soc Nephrol. 2015 Jul;26(7):1701-10. doi:10.1681/ASN.2014030247. Epub 2014 Oct 27. PMID:25349203.
Ethun CG, Zamora IJ, Roth DR, Kale A, Cisek L, Belfort MA, Haeri S, Ruano R, Welty SE, Cassady CI, Olutoye OO, Cass DL. Outcomes of fetuses with lower urinary tract obstruction treated with vesicoamniotic shunt: a single-institution experience. J Pediatr Surg. 2013 May;48(5):956-62. doi:10.1016/j.jpedsurg.2013.02.011. PMID:23701767.
Askenazi D, Myones B, Kamdar A, Warren R, Perez M, De Guzman M, Minta A, Hicks MJ, Kale A. Outcomes of children with proliferative lupus nephritis: the role of protocol renal biopsy. Pediatr Nephrol. 2007 Jul;22(7):981-6. doi:10.1007/s00467-007-0447-9. Epub 2007 Mar 3. PMID:17334789.
Adrogue HE, Borillo J, Torres L, Kale A, Zhou C, Feig D, Merszei J, Johnson R, Lou YH. Coincident activation of Th2 T cells with onset of the disease and differential expression of GRO-gamma in peripheral blood leukocytes in minimal change disease. Am J Nephrol. 2007;27(3):253-61. doi:10.1159/000101371. Epub 2007 Mar 27. PMID:17389786.