Dennis Hartigan-O'Connor Lab

Publications

Ardeshir A*, Narayan NR*, Méndez-Lagares G*, Lu D, Rauch M, Huang Yong, Van Rompay KKA, Lynch SV, Hartigan-O’Connor DJ. (2014) Breast-fed and bottle-fed infant rhesus macaque develop distinct gut microbiotas and immune systems. Sci. Transl. Med. Sept 3; 6:252.

Hartigan-O’Connor DJ, Lin D, Ryan JC, Shvachko VA, Cozen ML, Segal MR, Terrault NA, Lanier LL, Manos MM, McCune JM. (2014) Monocyte activation by interferon α is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection. J Infect Dis. May 15;209(10):1602-12.

Kanthaswamy S, Elfenbein HA, Ardeshir A, Ng J, Hyde D, Smith DG, Lerche N. (2014) Familial aggregation of chronic diarrhea disease (CDD) in rhesus macaques (Macaca mulatta). Am J Primatol. Mar;76(3):262-70.

Estell KE, Dawson DR, Magdesian KG, Swain E, Laing ST, Siso S, Mapes S, Pusterla N. Quantitative Molecular Viral Loads in Seven Horses with Naturally Occurring Equid Herpesvirus-1. (2014) Equine Vet J. In press.

Ramsey JJ, Tran D, Giorgio M, Griffey SM, Koehne A, Laing ST, Taylor SL, Kim K, Cortopassi GA, Lloyd KC, Hagopian K, Tomilov AA, Migliaccio E, Pelicci PG, McDonald RB. (2014) The Influence of Shc Proteins on Life Span in Mice. J Gerontol A Biol Sci Med Sci. In press.

Ardeshir A, Oslund KL, Ventimiglia F, Yee J, Lerche NW, Hyde DM. (2013) Idiopathic microscopic colitis of rhesus macaques: quantitative assessment of colonic mucosa. Anat Rec (Hoboken). Aug;296(8):1169-79

Tanaka T, Lerche NW, Farver TB, Ardeshir A, Kass PH. (2013) Specific-pathogen-free status is associated with lower infant mortality rate in rhesus macaque (Macaca mulatta) colonies at the California National Primate Research Center. J Med Primatol. Aug;42(4):186-91.

Lemoy MJ, Westworth DR, Ardeshir A, Tarara RP. (2013) Reference intervals for preprandial and postprandial serum bile acid in adult rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci. Jul;52(4):444-7.

Méndez-Lagares G*, Romero-Sánchez MC*, Ruiz-Mateos E, Genebat M, Ferrando-Martínez S, Muñoz-Fernández MA, Pacheco YM, Leal M. (2013) Long-Term Suppressive Combined Antiretroviral Treatment Does Not Normalize the Serum Level of Soluble CD14. J Infect Dis. Apr 15;207:1221.

G. Sasseville, J. L. Mankowski, A. Baldessari, C. Harbison, S. Laing, S. Kaliyaperumal, K. Mätz-Rensing, A. D. Miller, L. D. Schmidt, J. Kaplan-Kees, E. J. Dick, Jr, J. R. Reader, D. Liu, L. K. Crawford, J. H. Lane, S. M. Corner, I. D. Pardo, M. G. Evans, R. Murnane, and K. A. Terio. (2013) Meeting Report: Emerging Respiratory Viral Infections and Nonhuman Primate Case Reports. Veterinary Pathology. Nov;50(6):1145-53.

Laing ST, Sammak R, Lemoy MJ, Tarara R. (2013) Metastatic hepatocellular carcinoma in a juvenile Rhesus macaque (Macaca mulatta). Comparative Medicine. Oct; 63(5): 448-453.

Miller CN, Hartigan-O’Connor DJ, Lee MS, Laidlaw G, Cornelissen IP, Matloubian M, Coughlin SR, McDonald DM, McCune JM. (2013) IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol. Aug;25(8):471-83.

Laing ST, Weber ES, Yabsley MJ, Shock BC, Grosset C, Petritz OA, Barr B, Reilly CM, Lowenstine LJ. (2013) Fatal hepatic tetratrichomoniasis in a juvenile Waldrapp Ibis (Geronticus eremita). Journal of Veterinary Diagnostic Investigation. Mar; 25(2): 277-81.

Broadhurst MJ, Ardeshir A, Kanwar B, Mirpuri J, Gundra UM, Leung JM, Wiens KE, Vujkovic-Cvijin I, Kim CC, Yarovinsky F, Lerche NW, McCune JM, Loke P. (2012) Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon. PLoS Pathog. Nov;8(11):e1003000.

Briz V, García D, Méndez-Lagares G, Ruiz-Mateos E, de Mulder M, Moreno-Pérez D, Navarro ML, León JA, de José MI, Ramos JT, Mellado MJ, González-Tomé MI, Leal M and Muñoz-Fernández MA. (2012) High prevalence of X4/DM-tropic variants in children and adolescents infected with HIV-1 by vertical transmission. Pediatr Infect Dis J. Oct;31:1048.

Díaz L*, Méndez-Lagares G*, Correa-Rocha R, Pacheco YM, Ferrando-Martínez S, Ruiz-Mateos E, Del Mar Del Pozo-Balado M, León JA, Gurbindo MD, de José MI, Leal M, Muñoz-Fernández MA. (2012) Detectable viral load aggravates immunosenescence features of CD8 T-cell subsets in vertically HIV-infected children. J Acquir Immune Defic Syndr. Aug 15;60:447.

Méndez-Lagares G*, Díaz L*, Correa R, León JA, Ferrando-Martínez S, Ruiz-Mateos E, Pozo-Balado MM, Gurbindo MD, de José MI, Muñoz-Fernández MA, Leal M and Pacheco YM. (2012) Specific patterns of CD4-associated immunosenescence in vertically HIV-infected subjects. Clin Microbiol Infect. Jun;19:558.

Hartigan-O’Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM. (2012) SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment. Sci Transl Med. May 30;4(136):136ra69

Méndez-Lagares G, Pozo-Balado MM, Genebat M, García-Pergañeda A, Leal M and Pacheco YM. (2012) Severe immune dysregulation affects CD4+CD25hiFoxP3+ Regulatory T-cells in HIV-infected patients with low-level CD4 T-cell repopulation despite suppressive HAART. J Infect Dis. May 15;205:1501.

Méndez-Lagares G, García-Pergañeda A, Pozo-Balado MM, Genebat M, Ruiz-Mateos E, García-García M, Muñoz-Fernández MA, Pacheco YM and Leal M. (2012) Differential alterations of the CD4 and CD8 T-cell subsets in HIV-infected patients on highly active antiretroviral therapy with low CD4 T-cell restoration. J Antimicrob Chemother. May;67:1228.

Pulido I, Machmach K, Romero-Sánchez MC, Genebat M, Méndez-Lagares G, Ruiz-Mateos E, Leal M. (2012) T-cell changes after a short-term exposure to maraviroc in HIV-infected patients are related to antiviral activity. J Infect. Apr;64:417.

Laing ST, Ivens A, Butler V, Ravikumar SP, Laing R, Woods DJ, Gilleard JS. (2012) The transcriptional response of Caenorhabditis elegans to ivermectin exposure reveals novel genes involved in the response to reduced food intake. PLoS One. Feb 14;7(2):e31367.

*Authors contributed equally to this work.