Gopal Patel, M.D., Ph.D.

Hematopathology Fellow

Medical School: 
Saba University School of Medicine

Residency:
The Ohio State University Wexner Medical Center

Personal Interests:
Outdoor activities, Cooking, Gardening, Music/Movies

Reason for Choosing UC Davis:
UC Davis is among the best Institution in the nation dedicated to higher education, health care, research and public services. The faculty and staff are very supportive and foster learner-centered training programs. In addition, its strategic location in Sacramento afford well-balanced personal and professional lifestyle.

Clinical Interests:

• Hematopathology
• Transfusion Medicine
• Cytopathology

Research Interests:

• Basic and Clinical research in the areas of Hematopoietic Malignancies

CV Highlights/Brief Biography:

MD, Saba University School of Medicine, Saba, Caribbean Netherlands. (2014)

Postdoctoral Fellowship, Department of Physiology, University of Pennsylvania School of Medicine. (2008-09).

Postdoctoral Fellowship, Section of Hematology & Oncology, University of Chicago School of Medicine. (2006-07).

Ph.D., Molecular Biology & Genetics, University of Guelph, Canada. (2006).

M.Sc., Molecular Biology & Genetics, University of Guelph, Canada. (2002).

Refereed Journal Publications:

Moorwood, C.; Soni, N.; Patel, G. P.; Wilton, S. D.; Khurana, T. S. A cell-based highthroughput screening assay for posttranscriptional utrophin upregulation. J Biolmol Screen. 2013, 18(4), 400-406.

Basu, U.; Lozynska, O.; Moorwood, C.; Patel, G. P.; Wilton, S. D.; Khurana TS. Translational regulation of utrophin by miRNAs. PLoS One. 2011, 6(12), e29376.

Patel, G. P.; Baby, S. M.; Roy, A.; Lahiri; S. Calcium sensitivity for hypoxia in PGNs with PC12 cells in co-culture. Adv Exp Med Biol. 2009, 648, 121-124.

Patel, G. P.; Bag, J. IMP1 interacts with poly(A)-binding protein (PABP) and the autoregulatory translational control element of PABP-mRNA through the KH III-IV domain. FEBS J. 2006, 273(24), 5678-5690.

Patel, G. P.; Ma, S.; Bag, J. The autoregulatory translational control element of poly(A)-binding protein mRNA forms a heteromeric ribonucleoprotein complex. Nucleic Acids Res. 2005, 33(22), 7074-7089.

Reddy, K. K.; Oitomen, F. M.; Patel, G. P.; Bag, J. Perinuclear localization of slow troponin C mRNA in muscle cells is controlled by a cis-element located at its 3’ untranslated region. RNA, 2005, 11(3), 294-307.

Patent:

Moorwood, C.; Basu, U.; Patel, G.; Lozynska, O.; Khurana, T. S. Methods for enhancing utrophin production via inhibition of microRNA. U. S. Patent 20120122953, 2008.

Invited Talks:

Patel, G. P.; Basu, U.; Lozynska, O.; Bogdanovich, S.; Pistilli, E.; Baby, S. M; Khurana, T. S. miRNA-mediated translational regulation of utrophin mRNA by elements in its 5’ and 3’ UTRs. New directions in biology and disease of skeletal muscle meeting, 2008, New Orleans, Louisiana, USA.

Bag, J.; Patel, G. P.; Reddy, K. K.; Ma, S. The autoregulatory translational control element of Poly(A)-binding protein forms a multisubunit ribonucleoprotein complex with PABP, IMP1, and UNR. The RNA Society 10th annual meeting, 2005, Banff, Alberta, Canada.

Bag J.; Patel, G. P.; Musa, T. Poly(A)-binding protein I level is controlled by a feedback mechanism that involves PabpI binding to its own mRNA. RNA society of Japan 6th annual meeting, 2004, Kumamoto, Japan.

Research Presentations:

Jimenez, A.; Mitchell, R.; Kongtim, P.; Patel, G.; Kurbegovic, I.; Piggott, S.; Kanangat, S.; Katz, D.; Nathan, S.; Maciejewski, J. and Akpek, G. Major histocompatibility complex gammablock mismatch is associated with graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell recipients. 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation, 2016, Valencia, Spain.

Lakhanpal, V.; Patel, G. P.; Albukh, T.; Lakhanpal, R. Pars plana vitrectomy with endodrainge of chronic, refractory serous macular detachment associated with Optic disc pit. The 149th Annual American Ophthalmology Society meeting, 2013, La Jolla, CA, USA.

Ma, S.; Patel, G. P.; Bag, J. PABP binds to a novel destabilizing cis-element of MKK-2 mRNA and controls its stability. RNA Society 10th annual meeting, 2005, Banff, AB, Canada.

Patel, G. P.; Musa, T.; Ma, S.; Bag, J. Poly(A)-binding protein I autoregulates its mRNA translation. RNA Society 9th annual meeting, 2004, Madison, WI, USA.

Patel, G. P.; Bag, J. Feedback inhibition of Poly(A)-binding protein mRNA translation is mediated by a PABP-dependent autoregulatory ribonucleoprotein complex. Keystone Symposia meeting, 2003, Snowbird, UT, USA.

Patel, G. P.; Bag, J. Feedback inhibition of Poly(A)-binding protein mRNA translation is mediated by a Pabp1-dependent autoregulatory ribonucleoprotein complex. American Society for Cell Biology 42nd annual meeting, 2002, San Francisco, CA, USA.