Each year the Department of Pharmacology invites distinguished researchers to present their work on topics broadly related to pharmacology. Topics range from those closely aligned with the research interests of the department to areas of interest to researchers across the UC Davis campus and the UC Davis School of Medicine.
Past Seminars
2023
January 17, 2023
Speaker: Daniel Choquet, Ph.D., Director, Dynamic organization and function of Synapses, Bordeaux Neurocampus
Title: "Interplay between dynamic nanoscale glutamatergic synapse organization and function"
Host: Johannes Hell, Ph.D., Professor, Department of Pharmacology
February 21, 2023
The seminar has been cancelled!
Speaker: Daniela Kaufer, Ph.D., Department of Integrative Biology and Helen Wills Neuroscience Institute, Associate Dean of Biological Sciences, University of California, Berkley
Host: Angela Gelli, Ph.D., Professor, Department of Pharmacology
April 4, 2023
Speaker: Zhao Wang, Ph.D., Associate Professor, Departments of Diabetes and Cancer Metabolism, City of Hope
Title: “Protein Folding and Glucose Metabolism: Two-way Traffic in Cardiac Disease”
Host: Yang Kevin Xiang, Ph.D., Professor, Department of Pharmacology
April 18, 2023
Speaker: Fabrice Dabertrand, Ph.D., Associate Professor, Departments of Anesthesiology and Pharmacology, University of Colorado, Anschutz Medical Campus
Title: "Impact of cerebral small vessel disease on neuronal plasticity"
Host: Manuel Navedo, Ph.D., Professor, Department of Pharmacology
May 2, 2023
Speaker: Girija Raman, Ph.D., M.B.A., Associate Director of Corporate Development, Gilead
Title: "Anatomy of a Pharmaceutical Deal -Discovery to Acquisition"
Host: Heike Wullf, Ph.D., Professor, Department of Pharmacology
June 20, 2023
Speaker: Luis G Carvajal-Carmona, Ph.D., Associate Vice Chancellor for Academic Diversity Office of Diversity, Equity and Inclusion, Professor and Auburn Community Cancer Endowed Chair in Basic Science, Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis
Title: "Precision Health Equity: the intersection between modern medicine and health disparities"
Host: Elva Diaz, Ph.D., Professor, Department of Pharmacology
November 7, 2023
Speaker: David Liem, M.D., Ph.D., Project Scientist, Med: Internal Medicine Cardiology, UC Davis School of Medicine
Title: “A Natural Language Processing Approach to Unveil Novel Therapeutic Mechanisms and Targets in Heart Failure”
Host: Leighton T. Izu, Ph.D., Professor, Department of Pharmacology
2022
January 13, 2022
Speaker: Roy Ben-Shalom, Assistant Professor in Neurology and the MIND Institute, UC Davis
Title: “Simulating neurodevelopmental disorders: from the channel to the circuit”
Host: Julie Bossuyt, Ph.D., Associate Professor, Department of Pharmacology
Joint Seminar - Pharmacology - Physiology and Membrane Biology
February 15, 2022
Speaker: Michael Burton, Assistant Professor of Department of Neuroscience, University of Texas at Dallas
Title: "Cell and Sex-Specific effects of TLR4 in Neuroimmune interactions in acute pain states”
Host: Elva Diaz, Ph.D., Professor, Department of Pharmacology
March 15, 2022
Speaker: Jin Zhang, Professor, Department of Pharmacology, University of California, San Diego
Title: “Illuminating the Biochemical Activity Architecture of the Cell”
Hosts: Madeline Nieves-Cintron, Ph.D. and Lin Tian, Ph.D.
Joint Seminar - Pharmacology and Biochemistry
April 19, 2022
Speaker: Jennifer Davis, Associate Professor, Departments of Lab Medicine and Pathology and Bioengineering, Director of the Center for Cardiovascular Biology, Associate Director of The Institute for Stem Cell and Regenerative Medicine, School of Medicine, University of Washington
Title: "Regulators of Cardiac Fibroblast Fate and Fibrosis"
Host: Julie Bossuyt, Ph.D., Associate Professor, Department of Pharmacology
May 3, 2022
Speaker: Robert Edwards, Professor, M.D., Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco
Title: "The Frequency Dependence of Neurotransmitter Release"
Host: Johannes W. Hell, Ph.D., Professor, Department of Pharmacology
May 17, 2022
Speaker: Nikki Posnack, Assistant Professor, Dept. of Pediatrics, Dept of Pharmacology and Physiology, The George Washington University
Title: "Plastic – not so fantastic. Evaluating medical device biocompatibility using cardiac models"
Host: Crystal Ripplinger, Ph.D., Professor, Department of Pharmacology
October 18, 2022
Speaker: Jan Christoph, Ph.D., Assistant Professor, Cardiovascular Research Institute, University of California, San Francisco
Title: "High-Resolution Imaging of the Electromechanics of the Heart"
Host: Ye Chen-Izu, Ph.D., Professor, Department of Pharmacology
November 9, 2022
Speaker: Michael A Colman, Ph.D., F.H.E.A., Associate Professor, Department of Biological Sciences, Systems Physiology, University of Leeds, U.K.
Title: "Heterogeneity, variability, and cardiac dysfunction: from dyad to ECG"
Hosts: Eleonora Grandi, Ph.D. and Haibo Ni, Ph.D.
November 15, 2022
Speaker: Ade Aromolaran, Ph.D., Associate Professor, Department of Surgery, Division of Cardiothoracic Surgery, Investigator, Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), U2M2 Program in Molecular Medicine
Title: "Illuminating the Role of the Delayed Rectifier K Channels in Heart"
Host: Ele Grandi, Ph.D., Professor, Department of Pharmacology
2021
March 16, 2021
Speaker: Weijian Yang, Ph.D., Assistant Professor, Department of Electrical and Computer Engineering, University of California, Davis
Title: “All-optical Interrogation of Neural Circuits”
Host: Johannes W. Hell, Ph.D.
April 20, 2021
Speaker: Jiang Chang, M.D., Ph.D., FAPS, Professor, Chancellor EDGES Fellow, Center for Genomic and Precision Medicine, Texas A&M University
Title: "Rho Signaling: From Cardiac Remodeling to Hydrocephalus"
Host: Kevin Xiang, Ph.D.
May 18, 2021
Speaker: Devin Horton, Ph.D., Graduate Diversity Officer: Science, Technology, Engineering and Mathematics (STEM), University of California, Davis
Title: "Equity in Academia: A Group Project"
Host: Elva Diaz, Ph.D.
June 15, 2021
Speaker: Sue Vang, Engagement and Zero Waste Program Manager, University of California, Davis | Sustainability Office
Title: "Greening Your Workplace with UC Davis Sustainability"
Host: Andrew Edwards, Ph.D.
November 2, 2021
Speaker: Gabriela Popescu, Professor, Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences
Title: “NMDA Receptors as Calcium Channels”
Host: Johannes W. Hell, Ph.D.
2020
January 21, 2020
Speaker: Thomas M. Vondriska, Ph.D., Professor of Anesthesiology, Medicine and Physiology David Geffen School of Medicine at UCLA
Title: “Cardiovascular Epigenomes: From Chromatin Fiber to Human Populations”
Host: Julie Bossuyt, Ph.D.
April 21, 2020
Speaker: Jerod Denton, Ph.D., Professor, Department of Anesthesiology, Vanderbilt University
Host: Heike Wulff, Ph.D.
May 19, 2020
Speaker: Erika Boerman, Ph.D., Assistant Professor, Department Med Pharmacology and Physiology, University of Missouri
Host: Manuel Navedo, Ph.D.
June 23, 2020
Speaker: Federica Accornero, Ph.D., Associate Professor, The Ohio State University, Department of Physiology and Cell Biology
Host: Crystal Ripplinger, Ph.D.
September 15, 2020
Speaker: Dr. Osama Harraz, Research Assistant Professor, Department of Pharmacology, Larner College of Medicine, University of Vermont
Title: “PIP2: The maestro of the cerebral blood flow symphony”
Host: Madeline Nieves-Cintron, Ph.D.
October 20, 2020
Speaker: Dr. Federica Accornero, Assistant Professor, Physiology and Cell Biology, The Ohio State University
Title: "Insights into post-transcriptional control of gene expression in the heart"
Host: Crystal Ripplinger, Ph.D.
November 17, 2020
Speaker: Dr. Laurent Groc, Directeur Recherche CNRS, Group Leader, Directeur Adjoint, Institut Interdisciplinaire Neuroscience (IINS), Centre Broca Nouvelle-Aquitaine, CNRS – Université de Bordeaux
Title: “INMDA receptor signaling: old actor, new vista”
Host: Johannes W. Hell, Ph.D.
2019
January 15, 2019
Speaker: Hong Chen, Ph.D., Associate Professor of Surgery, Boston Children’s Hospital, Harvard Medical School
Title: “Endocytic Regulation of Cardiovascular Disease”
Host: Kevin Xiang, Ph.D.
February 12, 2019
Speaker: James Letts, Ph.D., Associate Professor, Dept. of Molecular and Cellular Biology, UC Davis
Title: “Structures of Respiratory Supercomplex I+III2 Suggest CoQ Channeling is Inefficient and Reveal Conformational Crosstalk”
Host: Johannes Hell, Ph.D.
February 19, 2019
Speaker: Filip Van Petegem, Ph.D., Professor, Department of Biochemistry and Molecular Biology, The University of British Columbia
Title: “Disease mutations at high resolution: structural insights into Calcium-selective channels”
Host: Don Bers, Ph.D.
March 19, 2019
Speaker: David J. Lefer, Ph.D. , Professor of Pharmacology, Director, Cardiovascular Center of Excellence, LSU Health New Orleans
Title: "Renal Sympathetic Denervation in Heart Failure"
Host: Kevin Xiang, Ph.D.
April 16, 2019
Speaker: Long-Sheng Song, M.D., M.S., Professor, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine
Title: “Decoding Junctophilin-2-mediated Transcriptome in Stressed Heart”
Host: Ye Chen-Izu, M.S., Ph.D.
May 21, 2019
Speaker: Carlo Brugnara, M.D., Professor of Pathology, Pathology, Boston Children’s Hospital, Harvard Medical School
Title: "Red blood cell hydration Status: from sickle cell disease to hereditary xerocytosis"
Host: Heike Wulff, Ph.D.
June 18, 2019
Speaker: Na Li, Ph.D., Assistant Professor, Molecular Physiology and Biophysics, Baylor College of Medicine
Title: “The emerging role of Inflammasome in cardiac arrhythmias.”
Host: Ele Grandi, Ph.D.
September 12, 2019
Speaker: Matthew B. Dalva, Ph.D., Professor and Vice Chair, Department of Neuroscience, Director, Jefferson Synaptic Biology Center, Thomas Jefferson University
Title: “Synapse formation and plasticity: effects of biological-sex and synaptic nanostructure”
Host: Elva Diaz, Ph.D.
September 17, 2019
Speaker: Maria Kurnikova, Ph.D., Associate Professor, Department of Chemistry at Carnegie Mellon University
Title: “Deciphering Molecular Mechanisms of the Glutamate Receptor Function”
Host: Elva Diaz, Ph.D.
October 15, 2019
Speaker: Zixi (Jack) Cheng, Ph.D., Associate Professor, University of Central Florida
Title: “Structural and Functional Mapping of Brain-Heart Connection and Remodeling”
Host: Chao-Yin Chen, Ph.D.
November 5, 2019
Speaker: Manu Ben-Johny, Ph.D., Assistant Professor of Physiology and Cellular Biophysics, Columbia University
Title: "Tuning calmodulin feedback of calcium and sodium channels in health and disease"
Host: Johannes W. Hell, Ph.D.
December 3, 2019
Speaker: Joshua I Goldhaber, M.D., Director, Division of Applied Cell Biology and Physiology at Cedars-Sinai Medical Center
Title: "Cardiac calcium regulation in mice with genetically modified calcium efflux proteins and in rats with Heart Failure with Preserved Ejection Fraction"
Host: Leighton Izu, Ph.D.
2018
January 16, 2018
Speaker: John Scott, Ph.D., University of Washington
Title: "Exploring and Exploiting the Spatial Constraints of Local Signaling"
Host: Manuel Navedo, Ph.D.
January 19, 2018
Speaker: Mark Ziolo, Ph.D., Ohio State University Medical Center
Title: "Therapeutic interventions for heart disease"
Host: Don Bers, Ph.D.
February 20, 2018
Speaker: Roger Nicoll M.D., University of California, San Francisco
Host: Johannes Hell, Ph.D.
March 20, 2018
Speaker: Yohannes Shiferaw, Ph.D., California State University, Northridge
Title: “Calcium waves, nonlinear dynamics, and stochasticity in atrial myocytes”
Host: Daisuke Sato, Ph.D.
April 17, 2018
Speaker: Miao Zhang, Ph.D., Chapman University, School of Pharmacy
Host: Heike Wulff, Ph.D.
May 15, 2018
Speaker: Nancy Kanagy, Ph.D., University of New Mexico
Host: Manuel Navedo, Ph.D.
June 19, 2018
Speaker: Alexey Glukhov, Ph.D., University of Wisconsin, School of Medicine
Host: Eleonora Grandi, Ph.D.
September 18, 2018
Speaker: Mark Mercola, Ph.D., Professor, Department of Medicine, Stanford University School of Medicine, Stanford Cardiovascular Institute
Host: Ele Grandi, Ph.D.
October 16, 2018
Speaker: Anthony J. Baker, Ph.D., Professor of Medicine, University of California, San Francisco, VA Medical Center, Cardiology Division
Title: “A new approach to treat right ventricular failure: targeting α1 adrenergic receptors”
Host: Ye Chen-Izu, M.S., Ph.D.
November 8, 2018
Speaker: Ingo Greger, Ph.D., Medical Research Council, Laboratory of Molecular Biology, Cambridge Biomedical Campus
Title: “Structural and functional architecture of the AMPA receptor extracellular region”
Host: Johannes Hell, Ph.D.
December 4, 2018
Speaker: David Schneider, Ph.D., Assistant Professor, Center for Neural Science, New York University
Title: “Cortical circuits for predicting the future”
Host: Crystal Ripplinger, Ph.D.
2017
January 17, 2017
Speaker: Matthew Kay, Ph.D., Associate Professor, BME Associate Chair for Research and Graduate Affairs BME, George Washington University
Title: "Neuron-specific approaches for altering cardiac autonomic tone in health and disease"
Host: Crystal Ripplinger, Ph.D.
February 21, 2017
Speaker: Tim McKinsey, Ph.D., Associate Professor and Associate Division Head for Translational Research, Division of Cardiology, University of Colorado, Denver
Title: "Multiple Roles for Protein Acetylation in Heart Failure"
Host: Julie Bossuyt, Ph.D.
March 10, 2017
Speaker: Emilia Entcheva, Ph.D., Professor, BME, George Washington University
Title: "Massively Parallel All-Optical Cardiac Electrophysiology"
Host: Daisuke Sato, Ph.D.
March 21, 2017
Speaker: Joan Heller Brown, Ph.D., Distinguished Professor, and Depart Chair Pharmacology, UCSD
Title: "Cardiomyocyte CaMkinase II regulates inflammatory and fibrotic responses associated with development of heart failure"
Host: Don Bers, Ph.D.
April 18, 2017
Speaker: Monika Davare, Ph.D., Research Instructor, Oregon Health and Science University
Title: "Kinase Fusions in Cancer: From Model Systems to the Development of Novel Therapeutics"
Host: Johannes Hell, Ph.D. and Mary Horne, Ph.D.
May 16, 2017
Speaker: Andrew Braun, Ph.D., Associate Professor, Physiology and Pharmacology, Physiology, Cumming School of Medicine, University of Calgary
Title: "Endothelial KCachannels: Critical mediators of vascular tone in health and disease"
Host: Heike Wulff, Ph.D.
July 21, 2017
Speaker: Catherine Proenza, Ph.D., Associate Professor, University of Colorado, Denver
Title: "Physiology and Biophysics of Cardiac Pacemaking"
Host: Eleonora Grandi, Ph.D.
September 14, 2017
Speaker: Kimberly Dodge-Kafka, Ph.D., University of Connecticut Health
Host: Don Bers, Ph.D.
September 19, 2017
Speaker: Martin Young, D.Phil, University of Alabama at Birmingham
Host: Kevin Xiang, Ph.D.
October 17, 2017
Speaker: Robert Malenka, Ph.D., Stanford University
Title: "Molecular mechanisms of AMPA receptor delivery and stabilization during LTP"
Host: Johannes Hell, Ph.D.
November 7, 2017
Speaker: Chris Glembotski, Ph.D., San Diego State University
Title: "The Transcription Factor, ATF6, Links ER Stress and Oxidative Stress Signaling in the Heart and is as Master Regulator of Cardiokine Secretion"
Host: Kevin Xiang, Ph.D.
November 9, 2017
Speaker: Johannes Backs, Ph.D., University of Heidelberg
Host: Don Bers, Ph.D. and Julie Bossuyt, Ph.D.
December 5, 2017
Speaker: George Rodney, Ph.D., Baylor College of Medicine
Title: "Role of NADPH Oxidase in Duchenne Muscular Dystrophy"
Host: Ye Chen-Izu, Ph.D.
2016
February 16, 2016
Speaker: Flavio Fenton, Ph.D., Associate Professor, Georgia Tech, Atlanta, GA
Title: "From Chaos to Cures; controlling the complex spatiotemporal dynamics of cardiac arrhythmias using a theoretical, numerical and experimental integrative approach"
Host: Daisuke Sato, Ph.D.
March 15, 2016
Speaker: Jennifer Whistler, Ph.D., Professor, Neurology, University of California, San Francisco
Title: "Translational opportunities in substance abuse and its co-morbidities through biased agonism at GPCRs"
Host: Elva Diaz, Ph.D.
March 31, 2016
Speaker: William E. Louch, Ph.D., Professor, Oslo University Hospital, Ullevål
Title: "Dyadic Structure and Function in Cardiomyocytes: Implications for Heart Failure"
Host: Eleonora Grandi, Ph.D.
April 19, 2016
Speaker: Alexander Dunn, Ph.D., Assistant Professor of Clinical Engineering, Stanford University, CA
Title: "Biophysical basis for cellular force transduction"
Host: Ye Chen-Izu, Ph.D.
May 17, 2016
Speaker: Eric Sobie, Ph.D., Associate Professor, Mount Sinai Hospital, New York, NY
Title: "Quantitative Cardiovascular Systems Pharmacology: combining simulations and experiments to understand toxicity and efficacy of drugs"
Host: Eleonora Grandi, Ph.D.
June 2, 2016
Speaker: Shelly Tzlil, Ph.D., Assistant Professor, Technion-Israel Inst of Tech, Haifa, Israel
Title: "Mechanical communication in cardiac cell synchronized beating"
Host: Kevin Xiang, Ph.D.
August 16, 2016
Speaker: Prasad Sathyamangla, Ph.D., Molecular Biology Researcher, Cleveland Clinic, Cleveland, Ohio
Host: Kevin Xiang, Ph.D.
September 27, 2016
Speaker: Mark von Zastrow, M.D., Ph.D., Professor, Psychiatry and Cellularand Molecular Pharmacology, University of California, San Francisco
Title: "An inner life of GPCRs"
Host: Johannes Hell, Ph.D.
October 18, 2016
Speaker: Scott Earley, Ph.D., Professor, Pharmacology, University of Nevada, Reno
Title: "Sensory Functions of TRPA1 Channels in the Cerebral Endothelium"
Host: Manuel Navedo, Ph.D.
October 19, 2016
Speaker: Yumei Feng, M.D., Ph.D., Associate Professor, Pharmacology, University of Nevada, Reno
Title: "A How the Brain Controls Blood Pressure: Role of (Pro)renin Receptor"
Host: Chao-Yin Chen, Ph.D.
November 15, 2016
American Heart Association and Society for Neuroscience Meetings
2015
January 20, 2015
Speaker: Ehud Isacoff, Ph.D., Professor of Neurobiology, University of California, Berkeley
Host: Manuel Navedo, Ph.D.
February 17, 2015
Speaker: Hemal Patel, Ph.D., Associate Professor and Director, UC San Diego Cardiac/Neuro Protection Laboratories
Title: "Caveolae as capacitors for energy and metabolism: Implications for cardiac injury, aging and diabetes"
Host: Kevin Xiang, Ph.D.
March 9, 2015
Speaker: Zhuan Zhou, Ph.D., Professor and Senior Investigator, Institute of Molecular Medicine, Peking University
Title: "Norepinephrine release from sympathetic nerves in cardiac slices and in vivo: real time recording using electrochemical micro carbon fiber electrodes"
Host: Don Bers, Ph.D.
April 6, 2015
Speaker: Ariel Escobar, Ph.D., Professor, School of Engineering, University of California, Merced
Title: "Relationship between intracellular Ca2+ release and electrical excitability at intact heart level"
Host: Don Bers, Ph.D.
April 21, 2015
Speaker: Luis Cuello, Ph.D., Assistant Professor, Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas
Title: "A structural driven kinetic cycle for the pore domain of a K+ channel"
Host: Heike Wulff, Ph.D.
May 12, 2015
Speaker: Alan Verkman, M.D., Ph.D., Professor of Medicine and Physiology, Department of Medicine, University of California, San Francisco
Title: "Targeting cell membrane transporters to develop new drugs"
Host: Heike Wulff, Ph.D.
September 15, 2015
Speaker: Peter Kohl, Ph.D., Professor, Imperial College, London, UK
Title: "Marrying Fibroblast Myocyte Electrophysiology in Native Myocardium: something old, something new, something borrowed, something blue"
Host: Crystal Ripplinger, Ph.D.
October 20, 2015
Speaker: Benjamin Prosser, Ph.D., Assistant Professor of Physiology, University of Pennsylvania
Title: "Microtubule mechanics and mechanosignaling in the heart"
Host: Ye Chen-Izu, Ph.D.
November 17, 2015
Speaker: Vaidehi Nagarajan, Ph.D., Principal Investigator, City of Hope, Beckman Research Institute, Duarte, CA
Title: "Insights into dynamics and allosteric communication in G-protein-coupled receptors"
Host: Kevin Xiang, Ph.D.
December 8, 2015
Speaker: Amy Lee, Ph.D., Assistant Dean for Scientific Affairs, Carver College of Medicine, University of Iowa
Title: "Decalmodulation of voltage-gated CavCa2+ channels"
Host: Johannes Hell, Ph.D.
December 15, 2015
Speaker: Michael Higley, M.D., Ph.D., Assistant Professor of Neurobiology, Cellular Neuroscience, Neurodegeneration and Repair, New Haven, CT
Title: "Dendritic compartmentalization of electrical and biochemical signaling"
Host: Johannes Hell, Ph.D.
2014
January 21, 2014
Speaker: Mark Shapiro, University of Texas
Host: Manuel Navedo, Ph.D.
February 13, 2014
Speaker: Junko Kurokawa, Tokyo Medical and Dental
Host: Colleen Clancy, Ph.D.
February 14, 2014
Speaker: Annette Dolphin, London College
Host: Johannes Hell, Ph.D.
March 18, 2014
Speaker: Robert Ross, University of California, San Diego
Title: "Integrins and Cytoskeletal Proteins in the Cardiac Myocyte: More than Glue and Struts"
Host: Ye Chen-Izu, Ph.D.
April 15, 2014
Speaker: Merry Lindsey, The University of Mississippi
Title: "Proteomic strategies to identify novel extracellular matrix biomarkers of cardiac injury"
Host: Crystal Ripplinger, Ph.D.
May 12, 2014
Speaker: Yoram Rudy, Washington University
Title: "Noninvasive mapping of cardiac electrophysiology and arrhythmias in the intact human heart"
Host: Colleen Clancy, Ph.D.
June 17, 2014
Speaker: Katherine Roche, NIH/NINDS
Title: "Molecular Mechanisms Regulating Trafficking of Synaptic Proteins"
Host: Johannes Hell, Ph.D.
September 16, 2014
Speaker: Andres Maricq, M.D., Ph.D., Professor of Biology and Adjunct Professor of Neurology, University of Utah, Salt Lake City
Title: "Regulated Delivery and Removal of Synaptic Machinery"
Host: Elva Diaz, Ph.D.
October 21, 2014
Speaker: Kang Shen, Ph.D., Professor, Department of Biology, Stanford, Palo Alto, CA
Host: Johannes Hell, Ph.D.
November 18, 2014
Speaker: Marta Filizola, Ph.D., Associate Professor of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York
Title: "Modern Computer-Aided Drug Discovery Approaches for G Protein-Coupled Receptors"
Host: Colleen Clancy, Ph.D.
December 16, 2014
Speaker: Rong Tian, M.D., Ph.D., Professor, Anesthesiology and Pain Medicine, Bioengineering, and Adjunct Professor, Biochemistry, Pathology, University of Washington Medicine
Title: "Targeting Mitochondria for Heart Failure Therapy"
Host: Kevin Xiang, Ph.D.
December 18, 2014
Speaker: Robert Harvey, Ph.D., Professor, Molecular Biosciences, University of Nevada, Reno
Title: "Spatial and Temporal Aspects of cAMP Signaling in Cardiac Myocyte"
Host: Colleen Clancy, Ph.D.
2013
January 15, 2013
Speaker: Robert Eisenberg, Rush Medical College, Illinois
Host: Donald Bers, Ph.D.
February 11, 2013
Speaker: Paul Simpson, University of California, San Francisco
Host: Donald Bers, Ph.D.
March 19, 2013
Speaker: Marco Conti, University of California, San Francisco
Title: "Specificity of the Beta adrenergic signaling in cardiac myocytes: role of phosphodiesterases"
Host: Kevin Xiang, Ph.D.
March 26, 2013
Speaker: Pierre De Meyts, Novo-Nordisk
Title: "Molecular basis of metabolic and mitogenic effects of insulin, insulin analogues and insulin-like growth factors"
Host: Mary Horne, Ph.D.
April 16, 2013
Speaker: Jeremy Marks, University of Chicago
Title: "Membrane-targeted approaches to rescuing neurons from death following hypoxia-ischemia"
Host: Florin Despa, Ph.D.
September 17, 2013
Speaker: Vikram Shakkottai, University of Michigan
Host: Heike Wulff, Ph.D.
October 15, 2013
Speaker: Fara Sheikh, UC San Diego
Title: "Deciphering the Electrical ‘Cross-Talk’ Underlying A Role for Desmosomal Cell-Cell Junctions in Cardiac Muscle Biology and Disease"
Host: Y Chen-Izu, Ph.D.
December 10, 2013
Speaker: Joseph Wu, Stanford University
Host: Kevin Xiang, Ph.D.
2012
September 7, 2012
Speaker: Kent E Pinkerton, University of California, Davis
September 21, 2012
Speaker: David Yue, John Hopkins University
Title: "Calcium channel modulation involves calmodulin on the move"
October 19, 2012
Speaker: Paul D. Allen, University of California at Davis
Title: "Control of intracellular Ca2+ in skeletal muscle--inside and outside"
November 9, 2012
Speaker: Alessandra Renieri, University of Siena, Italy
November 29, 2012
Speaker: John E. Casida (Emeriti Professor of Department of Environmental Science, Policy, and Management, University of California, Berkeley)
Title: "G ABA Receptor Games and Pesticide Puzzles"
Sponsored by: The UC Davis CounterAct Center for Excellence, Pharmacology Training Grant and Department of Pharmacology
December 7, 2012
Speaker: Virginia Brooks, Oregon Health Sciences University
2011
January 14, 2011
Speaker: Dan Minor, UC San Francisco
Title: "Ion channel modulation: structure, function, and unconventional approaches"
February 4, 2011
Speaker: Scott I. Simon, UC Davis, BME
Title: "Leukocyte guidance is signaled via B2-integrin and Orai1 during inflammatory recruitment"
February 18, 2011
Speaker: Susan Taylor, UC San Diego
Title: "Dynamics of Signaling by PKA"
March 29, 2011
Speaker: E. Dale Abel, University of Iowa
Title: "Novel Molecular Mechanisms Linking the Metabolic Syndrome with Cardiovascular Dysfunction"
April 8, 2011
Speaker: Coleen Murphy, Princeton University
Title: "Slowing the Ticking Clock: Using C. elegans to Discover Mechanisms Regulating Cognitive Aging Decline and Reproductive Cessation"
April 15, 2011
Speaker: A. Bora Inceoglu, UC Davis
Title: "Natural epoxy-fatty acids and soluble epoxide hydrolase: Emerging therapeutic targets for neurological disorders"
2010
January 22, 2010
Speaker: John Morser, Ph.D., Stanford School of Medicine
Title: "Role of Thrombin Activatable Fibrinolysis Inhibitor (TAFI)"
February 26, 2010
Speaker: Leonard Kaczmarek, Ph.D., Yale University
Title: "Regulation of sodium-activated potassium channels and the Fragile X Mental Retardation Protein signaling pathway"
April 23, 2010
Speaker: Laura Conforti, Ph.D., University of Cincinnati
Title: "Calcium signaling defects in autoimmunity: the ion channel viewpoint"
May 28, 2010
Speaker: Fernando Santana, Ph.D., University of Washington
Title: "Natural Inequalities: Why Some L-type Calcium Channels Work Harder than Others"
June 1, 2010
Speaker: Peter Sugden, Ph.D., Angela Clerk, Ph.D. Imperial College, London
Title: "Signaling Through Protein Kinases To Gene Expression In The Cardio Myocyte"
June 2, 2010
Speaker: J. Julius Zhu, Ph.D., University of Virginia
Title: "Central neural circuits and synapse"
September 10, 2010
Speaker: John Kuriyan, UC Berkeley
Title: "Structural Mechanisms of Protein Kinase Regulation"
November 12, 2010
Speaker: Laurent Groc, Universite Bordeaux, France
Title: "High resolution of imaging of NMDA receptors? Learning from a single molecule!"
November 18, 2010
Speaker: Yasunori Hayashi, Brain Science Institute, Japan
Title: "Molecular mechanisms of hippocampal synaptic plasticity"
December 3, 2010
Speaker: David Stellwagen, McGill University, Canada
Title: "The role of TNFalpha in synaptic plasticity and nervous system function"
2009
October 23, 2009
Speaker: Ariel Fernandez, Ph.D., Rice University
Title: "Translational concepts in drug discovery: Redesigning IMATINIB into a safer drug and taking it back to the clinic"
November 13, 2009
Speaker: Mariann Rots, Ph.D., University of Groningen
Title: "Awake the sleeping, mute the sleeping: towards targeted overwriting of epigenetic marks to moculate gene expression profiles"
December 4, 2009
Speaker: Bruce Hammock, Ph.D., UC Davis
Title: "Translating Soluble Epoxide Hydrolase Inhibitors into the Clinic, Picking the Right Target"
2008
February 29, 2008
Speaker: Edward Skolnik, Ph.D., New York University Medical Center
Title: "Regulation and function of the K channel KCa3.1: Role in T cell activation and polycystic kidney disease."
March 14, 2008
Speaker: Ricardo Dolmetsch, Ph.D., Stanford University
Title: The Secret Lives of Calcium Channels
2007
January 26, 2007
Speaker: Reinhold Penner, M.D., Ph.D., University of Hawaii at Manoa
Title: "CRACking the Molecular Components of Store-Operated Calcium Entry"
March 2, 2007
Speaker: John Rutledge, M.D., University of California, Davis
Title: "Triglyceride-Rich Lipoproteins: Friend or Foe?"
March 23, 2007
Speaker: Dirk Trauner, Ph.D., LMU Munich
Title: "Development of Light-Gated Ion Channels"
April 20, 2007
Speaker: Joel Mackay, Ph.D., School of Molecular and Microbial Biosciences, University of Sydney
Title: "The Wonderful World of Zinc Finger Domains"
May 11, 2007
Speaker: Matt Rasband, Ph.D., Baylor College of Medicine
Title: "Intrinsic and Extrinsic Determinants of Ion Channel Clustering in Neurons"
June 22, 2007
Speaker: Stephen D. Miller, Ph.D., Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University
Title: "The Inflamed CNS as a Neo-Lymphoid Organ - Implications for Specific Immunotherapy of MS"
September 28, 2007
Speaker: Mark Noble, Ph.D., University of Rochester
Title: ""Stem Cell Medicine: Building the Comprehensive Plan""
October 26, 2007
Speaker: Seth L. Robia, Ph.D., Loyola University Chicago
Title: "Using FRET to measure the binding affinity, binding kinetics, and structure of membrane protein complexes: Application to phospholamban and the cardiac calcium pump"
November 30, 2007
Speaker: Thomas DeCoursey, Ph.D., Rush University Medical Center
Title: "The intimate but controversial relationship between proton channels and the phagocyte NADPH oxidase"
December 14, 2007
Speaker: Ehud Isacoff, Ph.D., UC Berkeley
Title: "Can a Voltage Sensor also be a Gate?"
2006
January 20, 2006
Speaker: George Miljanich, Ph.D., Elan Pharmaceuticals
Title: "Killing Pain with Killer Snails: PRIALT, a Calcium Channel Blocking Analgesic from Marine Snail Venom"
February 17, 2006
Speaker: Robert Guy, M.D., Ph.D., NCI, National Institute of Health
Title: "Structure and Functional Mechanisms of Voltage-gated K+ Channels"
March 17, 2006
Speaker: Piepei Ping, Ph.D., University of California, Los Angeles
Title: "Proteomic Characterization of the Murine Cardiac 26S Proteasome Complexes"
June 16, 2006
Speaker: Pilar Blancafort, Ph.D., University of North Carolina at Chapel Hill
Title: "Reprogrammin tumor cells with artificial transcription factors"
June 30, 2006
Speaker: Isaac Pessah, Ph.D., University of California, Davis
Title: "Ryanodine receptors, chief integrators of cellular calcium signals at the cutting edge of health and disease"
October 13, 2006
Speaker: Richard Lewis, Ph.D., Stanford Medical School
Title: "The Dynamic Dyad: A Mechanism for Store-Operated Calcium Signaling"
November 2, 2006
Speaker: Bernd Fakler, M.D., University of Freiburg
Title: "Coupling of Cav and BKCa Channels Analyzed by Functional Proteomics"
2005
January 13, 2005
Speaker: Peter Walter, Ph.D., University of California, San Francisco
Title: "Intracellular Signaling From the Endoplasmic Reticulum to the Nucleus"
February 11, 2005
Speaker: Lawrence B. Salkoff, Ph.D., Washington University, School of Medicine
Title: "Novel Potassium Channels Revealed by the Comparative Genomic Approach"
March 11, 2005
Speaker: Robert S. Kass, Ph.D., Columbia University, School of Medicine
Title: "Ion Channel Mutations in Human Disease: Insights into Novel Cellular Physiology and Pharmacology"
April 8, 2005
Speaker: Ralph H. Joho, Ph.D., The University of Texas Southwestern Medical Center at Dallas
Title: "Ion Channels and Behavior: Sleep Loss and Motor Dysfunction in Kv3-deficient Mice"
April 22, 2005
Speaker: Doris A. Taylor, Ph.D., University of Minnesota School of Medicine
Title: "Cell-Based Cardiac and Vascular Repair: What Does the Future Hold?"
May 20, 2005
Speaker: Russell N. Van Gelder, M.D., Ph.D., Washington University School of Medicine
Title: "Learning From the Pupils: Lessons in Non-visual Ocular Photoreception"
June 3, 2005
Speaker: Dan Shoemaker, Ph.D., GHC Technologies, Inc
Title: "Rapid and Ultrasensitive Detection of Pathogens Using Single Molecule Analysis with Quantum Dots: Applications in Biodefense and Clinical Diagnostics"
September 23, 2005
Speaker: Joe DeRisi, Ph.D., University of California, San Francisco
Title: "Bugs, Drugs and Microarrays: Genomic Approaches to Infectious Disease"
October 21, 2005
Speaker: Stefan Pulst, M.D., UCLA School of Medicine
Title: "Degenerative Ataxias: From Polyglutamine Proteins and Ion Channels"
November 18, 2005
Speaker: Joel Gottesfeld, Ph.D., Scripps Research Institute
Title: "Chemical Regulation of Gene Expression"
December 9, 2005
Speaker: George Chandy, M.D., Ph.D., University of California, Irvine
Title: "Targeting potassium channels for therapy of autoimmunity, ataxia and atherosclerosis"
See: Current Seminars