Frontiers in Pharmacology Lecture Series

Each year the Department of Pharmacology invites distinguished researchers to present their work on topics broadly related to pharmacology. Topics range from those closely aligned with the research interests of the department to areas of interest to researchers across the UC Davis campus and the UC Davis School of Medicine.

Past Seminars

2023


January 17, 2023

Speaker: Daniel Choquet, Ph.D., Director, Dynamic organization and function of Synapses, Bordeaux Neurocampus

Title: "Interplay between dynamic nanoscale glutamatergic synapse organization and function"

Host: Johannes Hell, Ph.D., Professor, Department of Pharmacology


February 21, 2023

The seminar has been cancelled!

Speaker: Daniela Kaufer, Ph.D., Department of Integrative Biology and Helen Wills Neuroscience Institute, Associate Dean of Biological Sciences, University of California, Berkley

Host: Angela Gelli, Ph.D., Professor, Department of Pharmacology

See the flyer »


April 4, 2023

Speaker: Zhao Wang, Ph.D., Associate Professor, Departments of Diabetes and Cancer Metabolism, City of Hope

Title: “Protein Folding and Glucose Metabolism: Two-way Traffic in Cardiac Disease”

Host: Yang Kevin Xiang, Ph.D., Professor, Department of Pharmacology


April 18, 2023

Speaker: Fabrice Dabertrand, Ph.D., Associate Professor, Departments of Anesthesiology and Pharmacology, University of Colorado, Anschutz Medical Campus

Title: "Impact of cerebral small vessel disease on neuronal plasticity"

Host: Manuel Navedo, Ph.D., Professor, Department of Pharmacology


May 2, 2023

Speaker: Girija Raman, Ph.D., M.B.A., Associate Director of Corporate Development, Gilead

Title: "Anatomy of a Pharmaceutical Deal -Discovery to Acquisition"

Host: Heike Wullf, Ph.D., Professor, Department of Pharmacology


June 20, 2023

Speaker: Luis G Carvajal-Carmona, Ph.D., Associate Vice Chancellor for Academic Diversity Office of Diversity, Equity and Inclusion, Professor and Auburn Community Cancer Endowed Chair in Basic Science, Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis

Title: "Precision Health Equity: the intersection between modern medicine and health disparities"

Host: Elva Diaz, Ph.D., Professor, Department of Pharmacology


November 7, 2023

Speaker: David Liem, M.D., Ph.D., Project Scientist, Med: Internal Medicine Cardiology, UC Davis School of Medicine

Title: “A Natural Language Processing Approach to Unveil Novel Therapeutic Mechanisms and Targets in Heart Failure”

Host: Leighton T. Izu, Ph.D., Professor, Department of Pharmacology


2022


January 13, 2022

Speaker: Roy Ben-Shalom, Assistant Professor in Neurology and the MIND Institute, UC Davis

Title: “Simulating neurodevelopmental disorders: from the channel to the circuit”

Host: Julie Bossuyt, Ph.D., Associate Professor, Department of Pharmacology

Joint Seminar - Pharmacology - Physiology and Membrane Biology


February 15, 2022

Speaker: Michael Burton, Assistant Professor of Department of Neuroscience, University of Texas at Dallas

Title: "Cell and Sex-Specific effects of TLR4 in Neuroimmune interactions in acute pain states”

Host: Elva Diaz, Ph.D., Professor, Department of Pharmacology


March 15, 2022

Speaker: Jin Zhang, Professor, Department of Pharmacology, University of California, San Diego

Title: “Illuminating the Biochemical Activity Architecture of the Cell”

Hosts: Madeline Nieves-Cintron, Ph.D. and Lin Tian, Ph.D.

Joint Seminar - Pharmacology and Biochemistry


April 19, 2022

Speaker: Jennifer Davis, Associate Professor, Departments of Lab Medicine and Pathology and Bioengineering, Director of the Center for Cardiovascular Biology, Associate Director of The Institute for Stem Cell and Regenerative Medicine, School of Medicine, University of Washington

Title: "Regulators of Cardiac Fibroblast Fate and Fibrosis"

Host: Julie Bossuyt, Ph.D., Associate Professor, Department of Pharmacology


May 3, 2022

Speaker: Robert Edwards, Professor, M.D., Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco

Title: "The Frequency Dependence of Neurotransmitter Release"

Host: Johannes W. Hell, Ph.D., Professor, Department of Pharmacology


May 17, 2022

Speaker: Nikki Posnack, Assistant Professor, Dept. of Pediatrics, Dept of Pharmacology and Physiology, The George Washington University

Title: "Plastic – not so fantastic. Evaluating medical device biocompatibility using cardiac models"

Host: Crystal Ripplinger, Ph.D., Professor, Department of Pharmacology


October 18, 2022

Speaker: Jan Christoph, Ph.D., Assistant Professor, Cardiovascular Research Institute, University of California, San Francisco

Title: "High-Resolution Imaging of the Electromechanics of the Heart"

Host: Ye Chen-Izu, Ph.D., Professor, Department of Pharmacology


November 9, 2022

Speaker: Michael A Colman, Ph.D., F.H.E.A., Associate Professor, Department of Biological Sciences, Systems Physiology, University of Leeds, U.K.

Title: "Heterogeneity, variability, and cardiac dysfunction: from dyad to ECG"

Hosts: Eleonora Grandi, Ph.D. and Haibo Ni, Ph.D.


November 15, 2022

Speaker: Ade Aromolaran, Ph.D., Associate Professor, Department of Surgery, Division of Cardiothoracic Surgery, Investigator, Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), U2M2 Program in Molecular Medicine

Title: "Illuminating the Role of the Delayed Rectifier K Channels in Heart"

Host: Ele Grandi, Ph.D., Professor, Department of Pharmacology

2021


March 16, 2021

Speaker: Weijian Yang, Ph.D., Assistant Professor, Department of Electrical and Computer Engineering, University of California, Davis

Title: “All-optical Interrogation of Neural Circuits”

Host: Johannes W. Hell, Ph.D.


April 20, 2021

Speaker: Jiang Chang, M.D., Ph.D., FAPS, Professor, Chancellor EDGES Fellow, Center for Genomic and Precision Medicine, Texas A&M University

Title: "Rho Signaling: From Cardiac Remodeling to Hydrocephalus"

Host: Kevin Xiang, Ph.D.


May 18, 2021

Speaker: Devin Horton, Ph.D., Graduate Diversity Officer: Science, Technology, Engineering and Mathematics (STEM), University of California, Davis

Title: "Equity in Academia: A Group Project"

Host: Elva Diaz, Ph.D.


June 15, 2021

Speaker: Sue Vang, Engagement and Zero Waste Program Manager, University of California, Davis | Sustainability Office

Title: "Greening Your Workplace with UC Davis Sustainability"

Host: Andrew Edwards, Ph.D.


November 2, 2021

Speaker: Gabriela Popescu, Professor, Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences

Title: “NMDA Receptors as Calcium Channels”

Host: Johannes W. Hell, Ph.D.


2020


January 21, 2020

Speaker: Thomas M. Vondriska, Ph.D., Professor of Anesthesiology, Medicine and Physiology David Geffen School of Medicine at UCLA

Title: “Cardiovascular Epigenomes: From Chromatin Fiber to Human Populations”

Host: Julie Bossuyt, Ph.D.


April 21, 2020

Speaker: Jerod Denton, Ph.D., Professor, Department of Anesthesiology, Vanderbilt University

Host: Heike Wulff, Ph.D.


May 19, 2020

Speaker: Erika Boerman, Ph.D., Assistant Professor, Department Med Pharmacology and Physiology, University of Missouri

Host: Manuel Navedo, Ph.D.


June 23, 2020

Speaker: Federica Accornero, Ph.D., Associate Professor, The Ohio State University, Department of Physiology and Cell Biology

Host: Crystal Ripplinger, Ph.D.


September 15, 2020

Speaker: Dr. Osama Harraz, Research Assistant Professor, Department of Pharmacology, Larner College of Medicine, University of Vermont

Title: “PIP2: The maestro of the cerebral blood flow symphony”

Host: Madeline Nieves-Cintron, Ph.D.


October 20, 2020

Speaker: Dr. Federica Accornero, Assistant Professor, Physiology and Cell Biology, The Ohio State University

Title: "Insights into post-transcriptional control of gene expression in the heart"

Host: Crystal Ripplinger, Ph.D.


November 17, 2020

Speaker: Dr. Laurent Groc, Directeur Recherche CNRS, Group Leader, Directeur Adjoint, Institut Interdisciplinaire Neuroscience (IINS), Centre Broca Nouvelle-Aquitaine, CNRS – Université de Bordeaux

Title: “INMDA receptor signaling: old actor, new vista”

Host: Johannes W. Hell, Ph.D.


2019


January 15, 2019

Speaker: Hong Chen, Ph.D., Associate Professor of Surgery, Boston Children’s Hospital, Harvard Medical School

Title: “Endocytic Regulation of Cardiovascular Disease”

Host: Kevin Xiang, Ph.D.


February 12, 2019

Speaker: James Letts, Ph.D., Associate Professor, Dept. of Molecular and Cellular Biology, UC Davis

Title: “Structures of Respiratory Supercomplex I+III2 Suggest CoQ Channeling is Inefficient and Reveal Conformational Crosstalk”

Host: Johannes Hell, Ph.D.


February 19, 2019

Speaker: Filip Van Petegem, Ph.D., Professor, Department of Biochemistry and Molecular Biology, The University of British Columbia

Title: “Disease mutations at high resolution: structural insights into Calcium-selective channels”

Host: Don Bers, Ph.D.


March 19, 2019

Speaker: David J. Lefer, Ph.D. , Professor of Pharmacology, Director, Cardiovascular Center of Excellence, LSU Health New Orleans

Title: "Renal Sympathetic Denervation in Heart Failure"

Host: Kevin Xiang, Ph.D.


April 16, 2019

Speaker: Long-Sheng Song, M.D., M.S., Professor, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine

Title: “Decoding Junctophilin-2-mediated Transcriptome in Stressed Heart”

Host: Ye Chen-Izu, M.S., Ph.D.


May 21, 2019

Speaker: Carlo Brugnara, M.D., Professor of Pathology, Pathology, Boston Children’s Hospital, Harvard Medical School

Title: "Red blood cell hydration Status: from sickle cell disease to hereditary xerocytosis"

Host: Heike Wulff, Ph.D.


June 18, 2019

Speaker: Na Li, Ph.D., Assistant Professor, Molecular Physiology and Biophysics, Baylor College of Medicine

Title: “The emerging role of Inflammasome in cardiac arrhythmias.”

Host: Ele Grandi, Ph.D.


September 12, 2019

Speaker: Matthew B. Dalva, Ph.D., Professor and Vice Chair, Department of Neuroscience, Director, Jefferson Synaptic Biology Center, Thomas Jefferson University

Title: “Synapse formation and plasticity: effects of biological-sex and synaptic nanostructure”

Host: Elva Diaz, Ph.D.


September 17, 2019

Speaker: Maria Kurnikova, Ph.D., Associate Professor, Department of Chemistry at Carnegie Mellon University

Title: “Deciphering Molecular Mechanisms of the Glutamate Receptor Function” 

Host: Elva Diaz, Ph.D.


October 15, 2019

Speaker: Zixi (Jack) Cheng, Ph.D., Associate Professor, University of Central Florida

Title: “Structural and Functional Mapping of Brain-Heart Connection and Remodeling”

Host: Chao-Yin Chen, Ph.D.


November 5, 2019

Speaker: Manu Ben-Johny, Ph.D., Assistant Professor of Physiology and Cellular Biophysics, Columbia University

Title: "Tuning calmodulin feedback of calcium and sodium channels in health and disease"

Host: Johannes W. Hell, Ph.D.


December 3, 2019

Speaker: Joshua I Goldhaber, M.D., Director, Division of Applied Cell Biology and Physiology at Cedars-Sinai Medical Center

Title: "Cardiac calcium regulation in mice with genetically modified calcium efflux proteins and in rats with Heart Failure with Preserved Ejection Fraction"

Host: Leighton Izu, Ph.D.


2018


January 16, 2018

Speaker: John Scott, Ph.D., University of Washington

Title: "Exploring and Exploiting the Spatial Constraints of Local Signaling"

Host: Manuel Navedo, Ph.D.


January 19, 2018

Speaker: Mark Ziolo, Ph.D., Ohio State University Medical Center

Title: "Therapeutic interventions for heart disease"

Host: Don Bers, Ph.D.


February 20, 2018

Speaker: Roger Nicoll M.D., University of California, San Francisco

Host: Johannes Hell, Ph.D.


March 20, 2018

Speaker: Yohannes Shiferaw, Ph.D., California State University, Northridge

Title: “Calcium waves, nonlinear dynamics, and stochasticity in atrial myocytes”

Host: Daisuke Sato, Ph.D.


April 17, 2018

Speaker: Miao Zhang, Ph.D., Chapman University, School of Pharmacy

Host: Heike Wulff, Ph.D.


May 15, 2018

Speaker: Nancy Kanagy, Ph.D., University of New Mexico

Host: Manuel Navedo, Ph.D.


June 19, 2018

Speaker: Alexey Glukhov, Ph.D., University of Wisconsin, School of Medicine

Host: Eleonora Grandi, Ph.D.


September 18, 2018

Speaker: Mark Mercola, Ph.D., Professor, Department of Medicine, Stanford University School of Medicine, Stanford Cardiovascular Institute

Host: Ele Grandi, Ph.D.


October 16, 2018

Speaker: Anthony J. Baker, Ph.D., Professor of Medicine, University of California, San Francisco, VA Medical Center, Cardiology Division

Title: “A new approach to treat right ventricular failure: targeting α1 adrenergic receptors”

Host: Ye Chen-Izu, M.S., Ph.D.


November 8, 2018

Speaker: Ingo Greger, Ph.D., Medical Research Council, Laboratory of Molecular Biology, Cambridge Biomedical Campus

Title: “Structural and functional architecture of the AMPA receptor extracellular region”

Host: Johannes Hell, Ph.D.


December 4, 2018

Speaker: David Schneider, Ph.D., Assistant Professor, Center for Neural Science, New York University

Title: “Cortical circuits for predicting the future”

Host: Crystal Ripplinger, Ph.D.

2017


January 17, 2017

Speaker: Matthew Kay, Ph.D., Associate Professor, BME Associate Chair for Research and Graduate Affairs BME, George Washington University

Title: "Neuron-specific approaches for altering cardiac autonomic tone in health and disease"

Host: Crystal Ripplinger, Ph.D.


February 21, 2017

Speaker: Tim McKinsey, Ph.D., Associate Professor and Associate Division Head for Translational Research, Division of Cardiology, University of Colorado, Denver

Title: "Multiple Roles for Protein Acetylation in Heart Failure"

Host: Julie Bossuyt, Ph.D.


March 10, 2017

Speaker: Emilia Entcheva, Ph.D., Professor, BME, George Washington University

Title: "Massively Parallel All-Optical Cardiac Electrophysiology"

Host: Daisuke Sato, Ph.D.


March 21, 2017

Speaker: Joan Heller Brown, Ph.D., Distinguished Professor, and Depart Chair Pharmacology, UCSD

Title: "Cardiomyocyte CaMkinase II regulates inflammatory and fibrotic responses associated with development of heart failure"

Host: Don Bers, Ph.D.


April 18, 2017

Speaker: Monika Davare, Ph.D., Research Instructor, Oregon Health and Science University

Title: "Kinase Fusions in Cancer: From Model Systems to the Development of Novel Therapeutics"

Host: Johannes Hell, Ph.D. and Mary Horne, Ph.D.


May 16, 2017

Speaker: Andrew Braun, Ph.D., Associate Professor, Physiology and Pharmacology, Physiology, Cumming School of Medicine, University of Calgary

Title: "Endothelial KCachannels: Critical mediators of vascular tone in health and disease"

Host: Heike Wulff, Ph.D.


July 21, 2017

Speaker: Catherine Proenza, Ph.D., Associate Professor, University of Colorado, Denver

Title: "Physiology and Biophysics of Cardiac Pacemaking"

Host: Eleonora Grandi, Ph.D.


September 14, 2017

Speaker: Kimberly Dodge-Kafka, Ph.D., University of Connecticut Health

Host: Don Bers, Ph.D.


September 19, 2017

Speaker: Martin Young, D.Phil, University of Alabama at Birmingham

Host: Kevin Xiang, Ph.D.


October 17, 2017

Speaker: Robert Malenka, Ph.D., Stanford University

Title: "Molecular mechanisms of AMPA receptor delivery and stabilization during LTP"

Host: Johannes Hell, Ph.D.


November 7, 2017

Speaker: Chris Glembotski, Ph.D., San Diego State University

Title: "The Transcription Factor, ATF6, Links ER Stress and Oxidative Stress Signaling in the Heart and is as Master Regulator of Cardiokine Secretion"

Host: Kevin Xiang, Ph.D.


November 9, 2017

Speaker: Johannes Backs, Ph.D., University of Heidelberg

Host: Don Bers, Ph.D. and Julie Bossuyt, Ph.D.


December 5, 2017

Speaker: George Rodney, Ph.D., Baylor College of Medicine

Title: "Role of NADPH Oxidase in Duchenne Muscular Dystrophy"

Host: Ye Chen-Izu, Ph.D.


2016


February 16, 2016

Speaker: Flavio Fenton, Ph.D., Associate Professor, Georgia Tech, Atlanta, GA

Title: "From Chaos to Cures; controlling the complex spatiotemporal dynamics of cardiac arrhythmias using a theoretical, numerical and experimental integrative approach"

Host: Daisuke Sato, Ph.D.


March 15, 2016

Speaker: Jennifer Whistler, Ph.D., Professor, Neurology, University of California, San Francisco

Title: "Translational opportunities in substance abuse and its co-morbidities through biased agonism at GPCRs"

Host: Elva Diaz, Ph.D.


March 31, 2016

Speaker: William E. Louch, Ph.D., Professor, Oslo University Hospital, Ullevål

Title: "Dyadic Structure and Function in Cardiomyocytes: Implications for Heart Failure"

Host: Eleonora Grandi, Ph.D.


April 19, 2016

Speaker: Alexander Dunn, Ph.D., Assistant Professor of Clinical Engineering, Stanford University, CA

Title: "Biophysical basis for cellular force transduction"

Host: Ye Chen-Izu, Ph.D.


May 17, 2016

Speaker: Eric Sobie, Ph.D., Associate Professor, Mount Sinai Hospital, New York, NY

Title: "Quantitative Cardiovascular Systems Pharmacology: combining simulations and experiments to understand toxicity and efficacy of drugs"

Host: Eleonora Grandi, Ph.D.


June 2, 2016

Speaker: Shelly Tzlil, Ph.D., Assistant Professor, Technion-Israel Inst of Tech, Haifa, Israel

Title: "Mechanical communication in cardiac cell synchronized beating"

Host: Kevin Xiang, Ph.D.


August 16, 2016

Speaker: Prasad Sathyamangla, Ph.D., Molecular Biology Researcher, Cleveland Clinic, Cleveland, Ohio

Host: Kevin Xiang, Ph.D.


September 27, 2016

Speaker: Mark von Zastrow, M.D., Ph.D., Professor, Psychiatry and Cellularand Molecular Pharmacology, University of California, San Francisco

Title: "An inner life of GPCRs"

Host: Johannes Hell, Ph.D.


October 18, 2016

Speaker: Scott Earley, Ph.D., Professor, Pharmacology, University of Nevada, Reno

Title: "Sensory Functions of TRPA1 Channels in the Cerebral Endothelium"

Host: Manuel Navedo, Ph.D.


October 19, 2016

Speaker: Yumei Feng, M.D., Ph.D., Associate Professor, Pharmacology, University of Nevada, Reno

Title: "A How the Brain Controls Blood Pressure: Role of (Pro)renin Receptor"

Host: Chao-Yin Chen, Ph.D.


November 15, 2016

American Heart Association and Society for Neuroscience Meetings


2015


January 20, 2015

Speaker: Ehud Isacoff, Ph.D., Professor of Neurobiology, University of California, Berkeley

Host: Manuel Navedo, Ph.D.


February 17, 2015

Speaker: Hemal Patel, Ph.D., Associate Professor and Director, UC San Diego Cardiac/Neuro Protection Laboratories

Title: "Caveolae as capacitors for energy and metabolism: Implications for cardiac injury, aging and diabetes"

Host: Kevin Xiang, Ph.D.


March 9, 2015

Speaker: Zhuan Zhou, Ph.D., Professor and Senior Investigator, Institute of Molecular Medicine, Peking University

Title: "Norepinephrine release from sympathetic nerves in cardiac slices and in vivo: real time recording using electrochemical micro carbon fiber electrodes"

Host: Don Bers, Ph.D.


April 6, 2015

Speaker: Ariel Escobar, Ph.D., Professor, School of Engineering, University of California, Merced

Title: "Relationship between intracellular Ca2+ release and electrical excitability at intact heart level"

Host: Don Bers, Ph.D.


April 21, 2015

Speaker: Luis Cuello, Ph.D., Assistant Professor, Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas

Title: "A structural driven kinetic cycle for the pore domain of a K+ channel"

Host: Heike Wulff, Ph.D.


May 12, 2015

Speaker: Alan Verkman, M.D., Ph.D., Professor of Medicine and Physiology, Department of Medicine, University of California, San Francisco

Title: "Targeting cell membrane transporters to develop new drugs"

Host: Heike Wulff, Ph.D.


September 15, 2015

Speaker: Peter Kohl, Ph.D., Professor, Imperial College, London, UK

Title: "Marrying Fibroblast Myocyte Electrophysiology in Native Myocardium: something old, something new, something borrowed, something blue"

Host: Crystal Ripplinger, Ph.D.


October 20, 2015

Speaker: Benjamin Prosser, Ph.D., Assistant Professor of Physiology, University of Pennsylvania

Title: "Microtubule mechanics and mechanosignaling in the heart"

Host: Ye Chen-Izu, Ph.D.


November 17, 2015

Speaker: Vaidehi Nagarajan, Ph.D., Principal Investigator, City of Hope, Beckman Research Institute, Duarte, CA

Title: "Insights into dynamics and allosteric communication in G-protein-coupled receptors"

Host: Kevin Xiang, Ph.D.


December 8, 2015

Speaker: Amy Lee, Ph.D., Assistant Dean for Scientific Affairs, Carver College of Medicine, University of Iowa

Title: "Decalmodulation of voltage-gated CavCa2+ channels"

Host: Johannes Hell, Ph.D.


December 15, 2015

Speaker: Michael Higley, M.D., Ph.D., Assistant Professor of Neurobiology, Cellular Neuroscience, Neurodegeneration and Repair, New Haven, CT

Title: "Dendritic compartmentalization of electrical and biochemical signaling"

Host: Johannes Hell, Ph.D.


2014


January 21, 2014

Speaker: Mark Shapiro, University of Texas

Host: Manuel Navedo, Ph.D.


February 13, 2014

Speaker: Junko Kurokawa, Tokyo Medical and Dental

Host: Colleen Clancy, Ph.D.


February 14, 2014

Speaker: Annette Dolphin, London College

Host: Johannes Hell, Ph.D.


March 18, 2014

Speaker: Robert Ross, University of California, San Diego

Title: "Integrins and Cytoskeletal Proteins in the Cardiac Myocyte: More than Glue and Struts"

Host: Ye Chen-Izu, Ph.D.


April 15, 2014

Speaker: Merry Lindsey, The University of Mississippi

Title: "Proteomic strategies to identify novel extracellular matrix biomarkers of cardiac injury"

Host: Crystal Ripplinger, Ph.D.


May 12, 2014

Speaker: Yoram Rudy, Washington University

Title: "Noninvasive mapping of cardiac electrophysiology and arrhythmias in the intact human heart"

Host: Colleen Clancy, Ph.D.


June 17, 2014

Speaker: Katherine Roche, NIH/NINDS

Title: "Molecular Mechanisms Regulating Trafficking of Synaptic Proteins"

Host: Johannes Hell, Ph.D.


September 16, 2014

Speaker: Andres Maricq, M.D., Ph.D., Professor of Biology and Adjunct Professor of Neurology, University of Utah, Salt Lake City

Title: "Regulated Delivery and Removal of Synaptic Machinery"

Host: Elva Diaz, Ph.D.


October 21, 2014

Speaker: Kang Shen, Ph.D., Professor, Department of Biology, Stanford, Palo Alto, CA

Host: Johannes Hell, Ph.D.


November 18, 2014

Speaker: Marta Filizola, Ph.D., Associate Professor of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York

Title: "Modern Computer-Aided Drug Discovery Approaches for G Protein-Coupled Receptors"

Host: Colleen Clancy, Ph.D.


December 16, 2014

Speaker: Rong Tian, M.D., Ph.D., Professor, Anesthesiology and Pain Medicine, Bioengineering, and Adjunct Professor, Biochemistry, Pathology, University of Washington Medicine

Title: "Targeting Mitochondria for Heart Failure Therapy"

Host: Kevin Xiang, Ph.D.


December 18, 2014

Speaker: Robert Harvey, Ph.D., Professor, Molecular Biosciences, University of Nevada, Reno

Title: "Spatial and Temporal Aspects of cAMP Signaling in Cardiac Myocyte"

Host: Colleen Clancy, Ph.D.

2013


January 15, 2013

Speaker: Robert Eisenberg, Rush Medical College, Illinois

Host: Donald Bers, Ph.D.


February 11, 2013

Speaker: Paul Simpson, University of California, San Francisco

Host: Donald Bers, Ph.D.


March 19, 2013

Speaker: Marco Conti, University of California, San Francisco

Title: "Specificity of the Beta adrenergic signaling in cardiac myocytes: role of phosphodiesterases"

Host: Kevin Xiang, Ph.D.


March 26, 2013

Speaker: Pierre De Meyts, Novo-Nordisk

Title: "Molecular basis of metabolic and mitogenic effects of insulin, insulin analogues and insulin-like growth factors"

Host: Mary Horne, Ph.D.


April 16, 2013

Speaker: Jeremy Marks, University of Chicago

Title: "Membrane-targeted approaches to rescuing neurons from death following hypoxia-ischemia"

Host: Florin Despa, Ph.D.


September 17, 2013

Speaker: Vikram Shakkottai, University of Michigan

Host: Heike Wulff, Ph.D.


October 15, 2013

Speaker: Fara Sheikh, UC San Diego

Title: "Deciphering the Electrical ‘Cross-Talk’ Underlying A Role for Desmosomal Cell-Cell Junctions in Cardiac Muscle Biology and Disease"

Host: Y Chen-Izu, Ph.D.


December 10, 2013

Speaker: Joseph Wu, Stanford University

Host: Kevin Xiang, Ph.D.


2012


September 7, 2012

Speaker: Kent E Pinkerton, University of California, Davis


September 21, 2012

Speaker: David Yue, John Hopkins University

Title: "Calcium channel modulation involves calmodulin on the move"


October 19, 2012

Speaker: Paul D. Allen, University of California at Davis

Title: "Control of intracellular Ca2+ in skeletal muscle--inside and outside"


November 9, 2012

Speaker: Alessandra Renieri, University of Siena, Italy


November 29, 2012

Speaker: John E. Casida (Emeriti Professor of Department of Environmental Science, Policy, and Management, University of California, Berkeley)

Title: "G ABA Receptor Games and Pesticide Puzzles"

Sponsored by: The UC Davis CounterAct Center for Excellence, Pharmacology Training Grant and Department of Pharmacology


December 7, 2012

Speaker: Virginia Brooks, Oregon Health Sciences University


2011


January 14, 2011

Speaker: Dan Minor, UC San Francisco

Title: "Ion channel modulation: structure, function, and unconventional approaches"


February 4, 2011

Speaker: Scott I. Simon, UC Davis, BME

Title: "Leukocyte guidance is signaled via B2-integrin and Orai1 during inflammatory recruitment"


February 18, 2011

Speaker: Susan Taylor, UC San Diego

Title: "Dynamics of Signaling by PKA"


March 29, 2011

Speaker: E. Dale Abel, University of Iowa

Title: "Novel Molecular Mechanisms Linking the Metabolic Syndrome with Cardiovascular Dysfunction"


April 8, 2011

Speaker: Coleen Murphy, Princeton University

Title: "Slowing the Ticking Clock: Using C. elegans to Discover Mechanisms Regulating Cognitive Aging Decline and Reproductive Cessation"


April 15, 2011

Speaker: A. Bora Inceoglu, UC Davis

Title: "Natural epoxy-fatty acids and soluble epoxide hydrolase: Emerging therapeutic targets for neurological disorders"


2010


January 22, 2010

Speaker: John Morser, Ph.D., Stanford School of Medicine

Title: "Role of Thrombin Activatable Fibrinolysis Inhibitor (TAFI)"


February 26, 2010

Speaker: Leonard Kaczmarek, Ph.D., Yale University

Title: "Regulation of sodium-activated potassium channels and the Fragile X Mental Retardation Protein signaling pathway"


April 23, 2010

Speaker: Laura Conforti, Ph.D., University of Cincinnati

Title: "Calcium signaling defects in autoimmunity: the ion channel viewpoint"


May 28, 2010

Speaker: Fernando Santana, Ph.D., University of Washington

Title: "Natural Inequalities: Why Some L-type Calcium Channels Work Harder than Others"


June 1, 2010

Speaker: Peter Sugden, Ph.D., Angela Clerk, Ph.D. Imperial College, London

Title: "Signaling Through Protein Kinases To Gene Expression In The Cardio Myocyte"


June 2, 2010

Speaker: J. Julius Zhu, Ph.D., University of Virginia

Title: "Central neural circuits and synapse"


September 10, 2010

Speaker: John Kuriyan, UC Berkeley

Title: "Structural Mechanisms of Protein Kinase Regulation"


November 12, 2010

Speaker: Laurent Groc, Universite Bordeaux, France

Title: "High resolution of imaging of NMDA receptors? Learning from a single molecule!"


November 18, 2010

Speaker: Yasunori Hayashi, Brain Science Institute, Japan

Title: "Molecular mechanisms of hippocampal synaptic plasticity"


December 3, 2010

Speaker: David Stellwagen, McGill University, Canada

Title: "The role of TNFalpha in synaptic plasticity and nervous system function"

2009


October 23, 2009

Speaker: Ariel Fernandez, Ph.D., Rice University

Title: "Translational concepts in drug discovery: Redesigning IMATINIB into a safer drug and taking it back to the clinic"


November 13, 2009

Speaker: Mariann Rots, Ph.D., University of Groningen

Title: "Awake the sleeping, mute the sleeping: towards targeted overwriting of epigenetic marks to moculate gene expression profiles"


December 4, 2009

Speaker: Bruce Hammock, Ph.D., UC Davis

Title: "Translating Soluble Epoxide Hydrolase Inhibitors into the Clinic, Picking the Right Target"


2008


February 29, 2008

Speaker: Edward Skolnik, Ph.D., New York University Medical Center

Title: "Regulation and function of the K channel KCa3.1: Role in T cell activation and polycystic kidney disease."


March 14, 2008

Speaker: Ricardo Dolmetsch, Ph.D., Stanford University

Title: The Secret Lives of Calcium Channels


2007


January 26, 2007

Speaker: Reinhold Penner, M.D., Ph.D., University of Hawaii at Manoa

Title: "CRACking the Molecular Components of Store-Operated Calcium Entry"


March 2, 2007

Speaker: John Rutledge, M.D., University of California, Davis

Title: "Triglyceride-Rich Lipoproteins: Friend or Foe?"


March 23, 2007

Speaker: Dirk Trauner, Ph.D., LMU Munich

Title: "Development of Light-Gated Ion Channels"


April 20, 2007

Speaker: Joel Mackay, Ph.D., School of Molecular and Microbial Biosciences, University of Sydney

Title: "The Wonderful World of Zinc Finger Domains"


May 11, 2007

Speaker: Matt Rasband, Ph.D., Baylor College of Medicine

Title: "Intrinsic and Extrinsic Determinants of Ion Channel Clustering in Neurons"


June 22, 2007

Speaker: Stephen D. Miller, Ph.D., Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University

Title: "The Inflamed CNS as a Neo-Lymphoid Organ - Implications for Specific Immunotherapy of MS"


September 28, 2007

Speaker: Mark Noble, Ph.D., University of Rochester

Title: ""Stem Cell Medicine: Building the Comprehensive Plan""


October 26, 2007

Speaker: Seth L. Robia, Ph.D., Loyola University Chicago

Title: "Using FRET to measure the binding affinity, binding kinetics, and structure of membrane protein complexes: Application to phospholamban and the cardiac calcium pump"


November 30, 2007

Speaker: Thomas DeCoursey, Ph.D., Rush University Medical Center

Title: "The intimate but controversial relationship between proton channels and the phagocyte NADPH oxidase"


December 14, 2007

Speaker: Ehud Isacoff, Ph.D., UC Berkeley

Title: "Can a Voltage Sensor also be a Gate?"


2006


January 20, 2006

Speaker: George Miljanich, Ph.D., Elan Pharmaceuticals

Title: "Killing Pain with Killer Snails: PRIALT, a Calcium Channel Blocking Analgesic from Marine Snail Venom"


February 17, 2006

Speaker: Robert Guy, M.D., Ph.D., NCI, National Institute of Health

Title: "Structure and Functional Mechanisms of Voltage-gated K+ Channels"


March 17, 2006

Speaker: Piepei Ping, Ph.D., University of California, Los Angeles

Title: "Proteomic Characterization of the Murine Cardiac 26S Proteasome Complexes"


June 16, 2006

Speaker: Pilar Blancafort, Ph.D., University of North Carolina at Chapel Hill

Title: "Reprogrammin tumor cells with artificial transcription factors"


June 30, 2006

Speaker: Isaac Pessah, Ph.D., University of California, Davis

Title: "Ryanodine receptors, chief integrators of cellular calcium signals at the cutting edge of health and disease"


October 13, 2006

Speaker: Richard Lewis, Ph.D., Stanford Medical School

Title: "The Dynamic Dyad: A Mechanism for Store-Operated Calcium Signaling"


November 2, 2006

Speaker: Bernd Fakler, M.D., University of Freiburg

Title: "Coupling of Cav and BKCa Channels Analyzed by Functional Proteomics"


2005


January 13, 2005

Speaker: Peter Walter, Ph.D., University of California, San Francisco

Title: "Intracellular Signaling From the Endoplasmic Reticulum to the Nucleus"


February 11, 2005

Speaker: Lawrence B. Salkoff, Ph.D., Washington University, School of Medicine

Title: "Novel Potassium Channels Revealed by the Comparative Genomic Approach"


March 11, 2005

Speaker: Robert S. Kass, Ph.D., Columbia University, School of Medicine

Title: "Ion Channel Mutations in Human Disease: Insights into Novel Cellular Physiology and Pharmacology"


April 8, 2005

Speaker: Ralph H. Joho, Ph.D., The University of Texas Southwestern Medical Center at Dallas

Title: "Ion Channels and Behavior: Sleep Loss and Motor Dysfunction in Kv3-deficient Mice"


April 22, 2005

Speaker: Doris A. Taylor, Ph.D., University of Minnesota School of Medicine

Title: "Cell-Based Cardiac and Vascular Repair: What Does the Future Hold?"


May 20, 2005

Speaker: Russell N. Van Gelder, M.D., Ph.D., Washington University School of Medicine

Title: "Learning From the Pupils: Lessons in Non-visual Ocular Photoreception"


June 3, 2005

Speaker: Dan Shoemaker, Ph.D., GHC Technologies, Inc

Title: "Rapid and Ultrasensitive Detection of Pathogens Using Single Molecule Analysis with Quantum Dots: Applications in Biodefense and Clinical Diagnostics"


September 23, 2005

Speaker: Joe DeRisi, Ph.D., University of California, San Francisco

Title: "Bugs, Drugs and Microarrays: Genomic Approaches to Infectious Disease"


October 21, 2005

Speaker: Stefan Pulst, M.D., UCLA School of Medicine

Title: "Degenerative Ataxias: From Polyglutamine Proteins and Ion Channels"


November 18, 2005

Speaker: Joel Gottesfeld, Ph.D., Scripps Research Institute

Title: "Chemical Regulation of Gene Expression"


December 9, 2005

Speaker: George Chandy, M.D., Ph.D., University of California, Irvine

Title: "Targeting potassium channels for therapy of autoimmunity, ataxia and atherosclerosis"