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Faculty Research Interests

Donald M. Bers, Ph.D.:  Cardiac muscle electrophysiology, calcium dynamics and contractile regulation: Molecules to Heart.

Julie Bossuyt, D.V.M., Ph.D.:  Cellular and molecular mechanisms of cardiac plasticity and disease.

Chao-Yin Chen, Ph.D.:  Central neuroplasticity in cardiovascular regulation.

Ye Chen-Izu, Ph.D.:  Cellular and molecular mechanisms of heart disease and biophysics of the cardiac muscle excitation, contraction coupling.

Yi-Je (Jay) Chen, D.V.M., Ph.D.:  Potassium channels in ischemic stroke and neuroinflammation.

Nipavan Chiamvimonvat, M.D.:  Functional roles of different isoforms of cardiac calcium channels using combined techniques of transgenic mouse models, gene silencing and patch-clamp recordings.

Colleen E. Clancy, Ph.D.:  Computational approaches to reveal mechanisms of excitability in the heart and brain.

Elva Diaz, Ph.D.:  Functional genomics of nervous system development.

Angela Gelli Ph.D.:  Virulence determinants of fungal pathogenesis.

Eleonora Grandi, Ph.D.:  Cellular mechanisms of complex cardiac arrhythmia diseases, such as heart failure and atrial fibrillation.

Johannes Hell Ph.D.:  Molecular basis of synaptic plasticity and the role of signaling complexes.

Mary C. Horne, Ph.D.:  Unconventional cyclin function during cellular growth, differentiation and stress responses.

Richard Horuk, Ph.D.:  Chemokine receptors as therapeutic targets both for autoimmunity and for the treatment of malaria.

Leighton Izu, Ph.D.:  Dynamics and stability of the cardiac control system.

Anne Knowlton, Ph.D.:  Understanding the role of protein localization and post-translational modification of heat shock proteins (HSPs) and the estrogen receptor in cardiovascular disease.

Manuel Navedo, Ph.D.:  Mechanisms of excitation - contraction and excitation - transcription coupling in arterial myocytes.

Crystal Ripplinger, Ph.D.:  Mechanisms of cardiac arrhythmias; cardiovascular molecular imaging.

Michael A. Rogawski, M.D., Ph.D.:  Cellular neurophysiology of ion channels; neurological therapeutics, with an emphasis on antiepileptic drugs and other epilepsy treatment approaches; treatment of traumatic brain injury and post-traumatic epilepsy.

Daisuke Sato, Ph.D.:  Mathematical modeling of action potential and calcium cycling. Nonlinear dynamics of cardiac phenomena including alternans, early and delayed afterdepolarizations, Ca sparks, Ca waves.

David Segal, Ph.D.:  Engineering zinc finger DNA-binding proteins for diagnostics and gene therapy.

Heike Wulff, Ph.D.:  Potassium channel modulators for the treatment of autoimmune and cardiovascular disease.

Yang K. Xiang, Ph.D.:  Neurohormonal regulation of GPCR signaling in heart failure and Alzheimer's diseases.