My ultimate goal is to understand how and when hypertension should be treated to improve renal health of children at risk for significant renal and cardiovascular morbidity.
My current research is focused on the role of hypertension in the development and progression of kidney disease in children with diabetes mellitus. Since diabetes and hypertension are the most common causes of cardiovascular and kidney disease among adults, hypertensive children with diabetes mellitus represents a vulnerable population at risk to develop substantial morbidity and mortality.
I am currently building a study cohort evaluating how often hypertension is missed in children with diabetes, what the prevalence of white coat hypertension is in children with diabetes, and what the cardiovascular consequences are of missed hypertension in children with diabetes. By concentrating on high risk children, I hope to identify the optimal management strategy for hypertension in children.
M.D., Temple University School of Medicine, Philadelphia, Pennsylvania, 1999
M.A.S., UC San Francisco, San Francisco, California, 2008
B.S., UC San Diego, La Jolla, California, 1994
Loma Linda University Medical Center, Loma Linda, California, 2003
UC San Francisco, San Francisco, California, 2007
American Board of Pediatrics, 2002
American Academy of Pediatrics
American Heart Association
American Society of Pediatric Nephrology
Honors and Awards
National Institute of Health, Pediatric Loan Repayment Program, 2006
Pediatric Resident Teaching Award, Loma Linda University Medical Center, 2002
American Academy of Pediatrics (AAP) Resident Research Grant, 2001
AAP Resident Travel Award, 2001
Loma Linda University Pediatric Research Grant, 2000
Provost Honors, University of California, San Diego, 1994
Select Recent Publications
Nguyen, S. Martz, K., Stablein, D., Neu, A. Waitlist status of Pediatric Dialysis Patients in North America. Pediatric Transplantation. 2011 Jun;154:376-83.
Nguyen, S., Choi, H.K., Lustig, R.H., and Hsu, C.Y.: Sugar Sweetened Beverages, Serum Uric Acid, and Blood Pressure in Adolescents. The Journal of Pediatrics. Jun 2009;154(6):807-813
Nguyen, S., McCulloch, C.E., Brakeman, P., Portale, A.A., and Hsu, C.Y.: Being Overweight Modifies the Association Between Cardiovascular Risk Factors and Microalbuminuria in Adolescents. Pediatrics. Jan 2008;121(1):37-45.
Nguyen, ST and Hsu, CY: Excess weight as a risk factor for kidney failure. Current Opinion in Nephrology and Hypertension. 2007 Mar; 162:71-6.
Kassavetis, GA; Nguyen, ST; Kobayashi, K; Kumar, A; Geiduschek, EP; Pisano, M: Cloning, expression, and function of TEC5, the gene encoding the B” component of Saccharomyces cerevisae RNA polymerase III transcription factor TFIIIB. Proceedings of the National Academy of Science 1995; 92(21):9786-90