All Articles

Red blood cell antigen phenotyping and genotyping

The main purpose of testing prior to transfusion is to provide the most compatible blood to the patient in order to minimize the risk of hemolytic transfusion reactions.

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CAP Inspections and the importance of informatics…

The College of American Pathology (CAP) systematically reviews and accredits laboratories across the U.S. to ensure these laboratories meet certain safety and patient care criteria.

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Rapid Combined Flu A/B and SARS-CoV-2 RNA Polymerase Chain Reaction Testing for Emergency and Ambulatory Care Settings

The primary means for diagnosing SARS-CoV-2 infection is by reverse transcriptase (RT) real-time polymerase chain reaction (PCR).

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GI biopsies with lymphoid aggregates: What does this mean?

Because the gastrointestinal (GI) tract is a site of continuous challenge by foreign antigens, it contains a well-developed immune system component.

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Introduction to Therapeutic Drug Monitoring and the Clinical Laboratory's Role

Therapeutic drug monitoring (TDM) is the practice of measuring drug concentrations in order to tailor dosages and maintain therapeutic levels in a patient’s bloodstream.

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Challenges and Implications of False Negative COVID-19 Testing

As communities across the U.S. struggle to cope with the effects of the COVID-19 pandemic, many have focused on the lack of widespread testing as a major roadblock to reopening the country.

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Infectious Diseases

Specimen Collection Practices for Microbiologic Culture

The culturing of microorganisms remains the mainstay of laboratory testing for infectious disease, even in an age of rapid and more cost-effective molecular testing.

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Vitreous fluid for primary intraocular lymphoma

Primary intraocular lymphomas (PIOLs) are a subset of primary central nervous system lymphoma arise from retina, vitreous, or optic nerve-with or without central nervous system (CNS) involvement.

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Staining Methods in Frozen Section: Best Lab Practices

Tissue staining during a frozen section is one of the most important steps in obtaining an accurate pathologic diagnosis.

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