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Antimicrobial Stewardship Program in Patient Care: A Closer Look at Wound Infections

Health care providers around the world face the growing challenge of rising rates of resistance of bacterial pathogens to antibiotics. This is particularly pronounced in the management of wound infections ....

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Reconstituted Whole Blood Transfusion Exchange in Neonatal Hyperbilirubinemia

The blood bank occasionally will receive requests for a transfusion exchange in a neonate with hyperbilirubinemia. Neonates with hyperbilirubinemia may necessitate hospital admissions with approximately 5-10% of all

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Infectious Diseases

Comparison of SARS-CoV-2 Specimen Types: Nasal Swabs, Nasopharyngeal Swabs and Beyond

The nasopharyngeal (NP) swab serves as the primary specimen type for respiratory molecular pathogen detection. During the novel coronavirus infectious disease (COVID) pandemic of 2019, the NP swab became the

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Coronavirus

Role of Quantitative Serology Testing for COVID-19

The current pandemic has led to considerable interest in COVID-19 related laboratory testing. The widespread distribution of the various vaccines, the emerging genetic variants of SARS-CoV-2 circulating around the

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An Overview of Prosthetic Joint Infection (PJI) Definition and Diagnosis

The numbers of primary total hip and knee arthroplasties have been increasing over time, with 332,000 total hip and 719,000 total knee arthroplasties performed in 2010 in the United States.

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Infectious Diseases

Hepatitis B Serologic Testing Methods

Hepatitis B virus (HBV) was first discovered in 1965. Briefly, HBV is a DNA virus from the Hepadnaviridae family which is spread via contaminated body fluids. After exposure, the virus enters hepatocytes and .....

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Plasma Exchange with Albumin Replacement for Alzheimer’s Disease

The guidelines on the use of therapeutic Apheresis in clinical practice published in JCP 2019 has showed strong consideration for the addition of a new fact sheet on Alzheimer’s disease (AD) based on the ....

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Fine Needle Aspiration (FNA)

FNA is a simple, safe, and Cost-effective procedure for patient with a mass. FNA is a biopsy procedure and should be considered in the same light as a surgical biopsy.

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Race and eGFR: Addressing Health Disparities in Chronic Kidney Disease

Starting on May 4, 2021, UC Davis Health will calculate estimated glomerular filtration (eGFR) rate without a parameter for race. African Americans are at high risk for chronic kidney disease (CKD).

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Infectious Diseases

Acid Fast Bacilli (AFB) Smear and Culture Testing

It is a foundational principle for any laboratory test procedure that the value of the test heavily relies on using specimens that have been properly collected, labelled, handled or stored prior to....

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The Importance of Trephine Biopsy and Aspirate in Bone Marrow Analysis

The morphologic analysis of bone marrow specimen is an essential part of comprehensive evaluation in the diagnosis of hematologic and certain non-hematologic disorders.

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Coronavirus

The SARS-CoV-2 Variant and its Impact on Diagnostic Testing

The new SARS-CoV-2 mutant (VOC 202012/01) has become the dominant variant in the United Kingdom (UK) with the first known case in the United States identified on December 29, 2020.

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