The Northern California Acute Care Research Consortium (NORCARES) was developed by a multidisciplinary team of physicians from UC Davis Health, Stanford Healthcare, and UCSF Health and serves as a hub within the SIREN network.

The Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) is a clinical trials network funded by the National Institutes of Health, with a goal to improve the outcomes of patients with neurologic, cardiac, respiratory and hematologic emergencies by identifying effective treatments given in the earliest stages of care.

The NORCARES Hub collaborates with and provides clinical trial support to over 30 hospitals and EMS agencies (spokes) in the Northern California and western region, drawing on large and diverse patient volumes, urban and rural geographies, and academic and community hospitals.

Participating Institutions

UC Davis Health
Stanford Healthcare
UCSF – Zuckerberg San Francisco General Hospital and Trauma Center
CPMC Davies
CPMC Van Ness
Highland Hospital
Intermountain Health Utah - McKay
Intermountain Health Utah - Medical Center
Intermountain Health Utah - St. George
Intermountain Health Utah - Utah Valley
Kaiser Permanente Antioch
Kaiser Permanente Fremont
Kaiser Permanente Manteca
Kaiser Permanente Modesto
Kaiser Permanente Oakland
Kaiser Permanente Richmond
Kaiser Permanente Roseville
Kaiser Permanente Sacramento
Kaiser Permanente San Francisco
Kaiser Permanente San Jose
Kaiser Permanente San Leandro
Kaiser Permanente San Rafael
Kaiser Permanente Santa Clara
Kaiser Permanente South Sacramento
Kaiser Permanente South San Francisco
Kaiser Permanente Walnut Creek
Mercy General Hospital
Mercy Hospital of Folsom
Mercy San Juan Medical Center
Queen's Medical Center
Stanford Health Care Tri-Valley 
UCSF Fresno
UCSF Parnassus

Emergency Medical Services

A partnership with high volume prehospital emergency medical service (EMS) systems across the region bolsters the NORCARES consortium by extending the reach and efficiency of prehospital clinical trials. EMS systems provide critical access to patients at the point of emergency care, enabling early and rapid enrollment in trials. This partnership enhances the consortium's ability to capture real-world, time-sensitive data, improves patient recruitment rates, and ensures diverse patient representation. By integrating EMS systems into the network, NORCARES can leverage their on-the-ground expertise, streamlined communication channels, and established trust within communities, ultimately strengthening the overall effectiveness and impact of our clinical trials.

Sacramento County

  • Sacramento Emergency Medical Services System
  • Sacramento Metropolitan Fire District Emergency Medical Services Division

San Mateo County

  • San Mateo County Emergency Medical Services Agency

Fresno County

  • American Ambulance Emergency Medical Services Agency

San Francisco County

  • San Francisco Emergency Medical Services Agency
  • San Francisco Fire Department

Alameda County

  • Alameda County Emergency Medical Services Agency

Honolulu County (HI)

  • Honolulu Emergency Medical Services System
  • Honolulu Fire Department

Salt Lake City

  • Salt Lake City Emergency Medical Services System

Air Emergency Medical Transport Services

  • Reach Air Medical Services
  • Stanford Life Flight Aeromedical Transport