I believe that healthcare is a partnership among the care team, the patient and his or her family. Healthcare decisions should be made jointly after detailed discussions of risks and benefits of treatment decisions. I do my best to insure that patients and their families have a thorough understanding of the physiological alterations underlying their illnesses such that they can make properly informed decisions. In our clinic, many of our patients start their care with us as infants and stay with us for 10 to 15 years or more. By the time they "graduate" from our clinic as young adults, they are like family to us. Creating a safe, nurturing medical home for families of children with chronic illnesses is one of our most important jobs as healthcare professionals.
Dr. Glaser's main clinical interest is type 1 diabetes in children. She also cares for children with type 2 diabetes as well as children with other endocrine disorders including thyroid conditions, adrenal gland conditions and disorders of growth and puberty.
Dr. Glaser's main research interest is type 1 diabetes in children. Much of her research focuses on diabetic ketoacidosis, a potentially life-threatening complication of type 1 diabetes. She also has conducted research into methods of optimizing other aspects of type 1 diabetes care.
Pediatric Endocrinology and Diabetes
B.A., Swarthmore College, Swarthmore PA 1986
M.D., Harvard Medical School, Boston MA 1990
Pediatrics/General Pediatrics, Children's Hospital, Boston MA 1990-1991
Pediatrics/General Pediatrics, Children's Hospital, Boston MA 1991-1993
Pediatrics/Pediatric Endocrinology, UC Davis Medical Center, Sacramento CA 1995-1997
Pediatrics/Pediatric Endocrinology, UC San Diego Medical Center, San Diego CA 1994-1995
Elected to Alpha Omega Alpha Honor Medical Society, 2019
Dean's Award for Research Excellence at UC Davis Medical Center, 2013
Dean's Professorship in Childhood Diabetes Research, 2011
Co-recipient, Richard C. Woodward Memorial Endowed Fund Research Award, 2005
Outstanding Teaching Award, UC Davis, 2000
The Role Model Award, UC Davis, Department of Pediatrics, 1999
Outstanding Fellow Teacher Award, UC San Diego, Department of Pediatrics, 1995
Best Doctors in America (1997-2020), 2020
Ghetti S, Kuppermann N, Rewers A, Myers SR, Schunk JE, Stoner MJ, Garro A, Quayle KS, Brown KM, Trainor JL, Tzimenatos L, DePiero AD, McManemy JK, Nigrovic LE, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Glaser NS; Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes. Diabetes Care. 2020 Nov;43(11):2768-2775. doi:10.2337/dc20-0187. Epub 2020 Sep 22. PMID:32962981.
Kuppermann N, Ghetti S, Schunk J, Stoner J, Rewers A, McManemy J, Myers S, Nigrovic L, Garro A, Brown K, Quayle K, Trainor J, Tzimenatos L, Bennett J, DePiero A, Kwok M, Perry C, Olsen C, Casper TC, Dean JM & Glaser N for the Pediatric Emergency Care Applied Research Network (PECARN) OKA FLUID Study Group. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. New England J Med. 2018 Jun 14;378:2275-87. doi:10.1056/NEJMoa1716816.
Lo W, O'Donnell M, Tancredi D, Orgain M, Glaser N. Diabetic ketoacidosis in juvenile rats is associated with reactive gliosis and activation of microglia in the hippocampus. Pediatr Diabetes. 2016 Mar;17(2):127-39. doi:10.1111/pedi.12251. Epub 2015 Jan 16. PMID:25594864.
Glaser NS, Tancredi DJ, Marcin JP, Caltagirone R, Lee Y, Murphy C, Kuppermann N. Cerebral hyperemia measured with near infrared spectroscopy during treatment of diabetic ketoacidosis in children. J Pediatr. 2013 Oct;163(4):1111-6. doi:10.1016/j.jpeds.2013.06.008. Epub 2013 Jul 18. PMID:23871731.
Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N; Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial. Pediatr Diabetes. 2013 Sep;14(6):435-46. doi:10.1111/pedi.12027. Epub 2013 Mar 13. PMID:23490311.
Glaser N, Ngo C, Anderson S, Yuen N, Trifu A, O'Donnell M. Effects of hyperglycemia and effects of ketosis on cerebral perfusion, cerebral water distribution, and cerebral metabolism. Diabetes. 2012 Jul;61(7):1831-7. doi:10.2337/db11-1286. Epub 2012 Apr 12. PMID:22498698.
Yuen N, Anderson SE, Glaser N, Tancredi DJ, O'Donnell ME. Cerebral blood flow and cerebral edema in rats with diabetic ketoacidosis. Diabetes. 2008 Oct;57(10):2588-94. doi:10.2337/db07-1410. Epub 2008 Jul 15. PMID:18633109.
Glaser NS, Wootton-Gorges SL, Buonocore MH, Tancredi DJ, Marcin JP, Caltagirone R, Lee Y, Murphy C, Kuppermann N. Subclinical cerebral edema in children with diabetic ketoacidosis randomized to 2 different rehydration protocols. Pediatrics. 2013 Jan;131(1):e73-80. doi:10.1542/peds.2012-1049. Epub 2012 Dec 10. PMID:23230065.
Glaser N, Yuen N, Anderson SE, Tancredi DJ, O'Donnell ME. Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide. Diabetes. 2010 Mar;59(3):702-9. doi:10.2337/db09-0635. Epub 2009 Dec 22. PMID:20028943.
Ghetti S, Lee JK, Sims CE, Demaster DM, Glaser NS. Diabetic ketoacidosis and memory dysfunction in children with type 1 diabetes. J Pediatr. 2010 Jan;156(1):109-14. doi:10.1016/j.jpeds.2009.07.054. PMID:19833353.