Francis R. Poulain, M.D.
- Associate Professor
- Director of Neonatal-Perinatal Training Program
- Health Sciences Clinical Professor
UC Davis Children's Hospital
2315 Stockton Blvd.
Sacramento, CA 95817
Additional Phone Numbers
Philosophy of Care
I strive to provide the best and most up to date care to critically ill neonates. I am committed to making my expertise available to physicians in the community in need of assistance.
Dr. Poulain is a Pediatrician, specialist of the diseases of the newborn, with a particular interest in fetal conditions that may be amenable to prenatal interventions and in the management of neonatal lung diseases.
Dr. Poulain has a long-standing interest in the biology of lung surfactant and its relevance to the management of neonatal lung diseases. He is an active member of the UC fetal-neonatal consortium, committed to improving academic collaboration between various UC campuses. He is involved in promoting telemedicine to assist Pediatricians in the community caring for neonates.
M.D., University of Medicine, Caen, 1975
B.S., Institut Notre-Dame, Avranches, Frances, 1969
Certificate, Universite Rene Descarte, Paris, 1979
University of Utah, Salt Lake City, Utah, 1985-1988
UC San Francisco, San Francisco, California, 1988-1991
American Board of Pediatrics, 1999
American Board of Pediatrics, Neonatal-Perinatal Medicine, 1999
American Academy of Pediatrics
American Academy of Pediatrics, Fellow
American Association for the Advancement of Science
American Thoracic Society
California Association of Neonatologists
Society for Pediatric Research
Western Society for Pediatric Research
Honors and Awards
A multi-centre, randomized, placebo-controlled, double-blind, two-armed, parallel group study to evaluate efficacy and safety of IV sildenafil in the treatment of neonates with persistent pulmonary hypertension or hypoxic respiratory failure. Site PI 2015, 2016, 2017, 2018, 2019
The sustained aeration of infants lungs (SAIL) study. Site PI 2015, 2016, 2017, 2018
Health Sciences Research Award, UCD (PI) 2003, 2004, 2005
Research Grant, Children's Miracle Network (PI) 2002, 2003
Research Grant RO1 (Co-investigator, HD38462) 2000, 2001
Program Project Grant (Project co-leader, HL24075) 1999, 2000, 2001
Research Grant RO1 (Co-principal Investigator, HL58047) 1997, 1998, 1999, 2000, 2001
American Lung Association Research Award (PI) 1993, 1994, 1995
Clinical Investigator Development Award (PI) 1993, 1994, 1995, 1996, 1997
Melvin Grumbach Research Award, UCSF, 1991
Laboratories Special Gold Medal For Excellence in Tropical Medicine, Paris, 1979
Select Recent Publications
Lipoyltransferase 1 Gene Defect Resulting in Fatal Lactic Acidosis in Two Siblings.
Taché V, Bivina L, White S, Gregg J, Deignan J, Boyadjievd SA, Poulain FR.
Case Rep Obstet Gynecol. May 10. 2016
Lusk LA, Brown EG, Overcash RT, Grogan TR, Keller RL, Kim JH, Poulain FR, Shew SB, Uy C, DeUgarte DA; University of California Fetal Consortium. Multi-institutional practice patterns and outcomes in uncomplicated gastroschisis: a report from the University of California Fetal Consortium (UCfC). J Pediatr Surg. Dec;49(12):1782-6, 2014
Hortob�gyi L, Kierstein S, Krytska K, Zhu X, Das AM, Poulain F, Haczku A. Surfactant protein D inhibits TNF-alpha production by macrophages and dendritic cells in mice. J Allergy Clin Immunol. 2008 Sep;122(3):521-8. Epub 2008 Jun 12.
Chiou HL, Diaz R, Orlino E Jr, Poulain FR. Acute airway obstruction by a sheared endotracheal intubation stylet sheath in a premature infant. J Perinatol. 2007 Nov;27(11):727-9.
Haczku A, Cao Y, Vass G, Kierstein S, Nath P, Atochina-Vasserman EN, Scanlon ST, Li L, Griswold DE, Chung KF, Poulain FR, Hawgood S, Beers MF, and Crouch EC. IL-4 and IL-13 Form a Negative Feedback Circuit with Surfactant Protein-D in the Allergic Airway Response. J Immunol. 176(6):3557-3565.
Kierstein S, Poulain FR, Cao Y, Grous M, Mathias R, Kierstein G, Beers MF, Salmon M, Panettieri RA Jr, Haczku A. Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D. Respir Res. 2006 Jun 1;7:85.
Sorensen GL, Madsen J, Kejling K, Tornoe I, Nielsen O, Townsend P, Poulain F, Nielsen CH, Reid KB, Hawgood S, Falk E, Holmskov U. Surfactant protein D is proatherogenic in mice. Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2286-94. Epub 2005 Dec 30.
Hawgood S, Brown C, Edmondson J, Stumbaugh A, Allen L, Goerke J, Clark H, and Poulain F. Pulmonary collectins modulate strain-specific type A influenza infection and host responses. J Virol. Aug, 78(16):8565-72, 2004
Atochina EN, Beers MF, Hawgood S, Poulain F, Davis C, Fusaro T, and Gow AJ. Surfactant Protein-D, a mediator of innate lung immunity, alters the products of NO metabolism. Am J Respir Cell Mol Biol. 30(3):271-9, 2004.
Atochina EN, Gow AJ, Beck JM, Haczka A, Inch A, Kadire H, Tomer Y, Davis C, Preston AM, Poulain F, Hawgood S, and Beers MF. Delayed clearance of pneumocystis carinii infection, increased inflammation, and altered nitric oxide metabolism in lungs of surfactant protein-D knockout mice. J Infect Dis. 189(8):1528-9, 2004.
John Michael's Reunion