Comparative Oncology

The Comparative Oncology Program draws on UC Davis' key strengths as the top-ranked veterinary school in the country. Research underway pertains to the disease mechanisms that are implicated in the genesis and progression of cancer. The Program seeks to understand the genetics, immunology, and microenvironment of tumors in the preclinical setting, using animal models which will provide insights into human cancer.

Its specific aims, include (1) elucidating the molecular and cellular mechanisms by which cellular and viral oncogenes and tumor suppressor genes are involved in tumor initiation, progression, and metastasis, (2) characterizing metabolic and immunologic tumor heterogeneity to inform cancer diagnosis and treatment, and (3) conducting preclinical trials using companion animal cancer patients in order to inform human cancer research and promote translation, especially in the area of innovative immunotherapy.