Molecular Oncology

The Molecular Oncology Program advances the understanding of the molecular and chemical basis of cancer and tumor progression, with specific aims regarding (1) defining mechanisms to maintain genome stability, (2) interrogating key signal transduction and hormone receptor pathways, and (3) understanding the role of energetics and metabolism in cancer. 

The Program seeks to promote rapid translation of basic discoveries of cancer mechanisms into the development of potential prognostic markers and therapeutic strategies.

Also studied are specific processes related to cancer cells, including the chemical and biochemical events involved in the DNA damage response, drug and radiation resistance, as well as hormone resistance. The Program offers expertise in molecular biology and biochemistry to cancer center investigators and fosters interactions with other research programs to develop disease-oriented translational research.