Clinical Trials | Neurological Surgery Research

Clinical Trials

Learn more about the various clinical trials and studies in the Department of Neurological Surgery.

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Neurological Surgery Research

Selected Clinical Trials
  • Brain-Computer Interface Clinical Trials

    • Feasibility of the BrainGate2 Neural Interface System in Persons with Tetraplegia
  • Deep Brain Stimulation

    • Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND) 
    • Dual frequency, dual region deep brain stimulation of the subthalamic nucleus in Parkinson's disease 
  • Neurocritical Care and Neurotrauma

    • The UCD-DGMC TBI Neural Network-Precision Medicine Paradigm for Complex Trauma 
    • Brain Oxygen Optimization in Severe Traumatic Brain Injury-Phase 3 (BOOST-3) 
    • An Early Feasibility Study for the Development of a Model to Non-invasively Estimate Intracranial Pressure and New Metrics of Cerebral Autoregulation using the CoMind One EFS Device
    • Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial (Bio-BOOST)
    • Electrocenphalography for cerebral trauma recovery and oxygenation (Electro-BOOST)
    • Transnasal sphenopalatine ganglion block for treatment of acute subarachnoid hemorrhage associated headache
  • Neurovascular

    • Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter (GUARD)
  • Spine Neurosurgery

    • A Randomized, Double-Blind, Placebo-Controlled Proof of Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Traumatic Cervical Spinal Cord Injury - M16-077 
    • A Concurrently Controlled Study of the LimiFlex" Paraspinous Tension Band in the Treatment of Lumbar Degenerative Spondylolisthesis with Spinal StenosisEmpirical Spine 
    • An Assessment of P-15L Bone Graft in Transforminal Lumbar Interbody Fusion with Instrumentation 
    • A Prospective, Randomized, Multi-Center, Open-Label Pilot Study of Infuse® Bone Graft with Mastergraft* Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of MultiLevel Degenerative Lumbosacral Spinal Conditions 
    • Quantitative measurement of spinal cord function in degenerative cervical myelopathy: a prospective observational longitudinal cohort study 
    • Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse Bone Graft and The Capstone* Spinal System with Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine 
    • Medtronic The Ailliance Post-Market Clinical Study: All enabling technoLogies, BioLogics, IDS, And core spiNe produCt collEction 
    • A Clinical Investigation Evaluating Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine
    • A Prospective, Multicenter, Randomized, Double-blind, controlled study to evaluate the efficacy and safety of a single injection of Rexlemestrocel-L combined with Hyaluronic acid (HA) in subjects with moderate to severe chronic low back pain