Caren Armstrong has a particular interest in how surgical interventions can be used clinically to help treat children with seizures. She has additional training in epilepsy surgical management, as well as in neuromodulation and neurogenetics in the context of epilepsy.
The laboratory investigates the underlying mechanisms that govern the development of epilepsy in children, including. This includes:
- A investigations into inhibitory interneuronal microcircuits, EEG analysis
- The use of intracranial stimulation to actively probe the network in patients undergoing intracranial EEG
- The use of neuromodulation, and mechanisms of genetic epilepsies
To investigate, we use analysis of EEG recordings and medical record data from patients as well as recording directly from cells in resected human tissue and from animal models of genetic causes of epilepsy.