T.A.N.D.Y. Lab | Neurology Research

Brad Ander, Ph.D., studies how genes react after brain injuries. He looks at different types of RNA—molecules that help turn DNA into proteins—to understand how they affect health and treatments. He also explores how people's unique genetic makeup changes the way RNA responds.
 
RNA acts as a bridge between DNA and proteins, constantly shifting in response to disease or injury. Some RNAs help make proteins, while others regulate biological processes. When the body moves from a healthy state to illness, the balance of these RNAs can change. By studying these shifts, researchers can find new ways to improve treatments.
 
Ander has researched gene activity in brain-related conditions like stroke, autism, and Alzheimer's disease. He works with other scientists, using advanced data analysis tools to better understand these disorders.

Boryana Stamova, M.S., M.S., Ph.D., conducts research focused on deciphering how gene expression changes in neurological disease and neurodevelopmental disorders, such as stroke and autism spectrum disorders. A large part of her research has been centered on different types of stroke, such as ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage.

The overarching goal of her studies is to advance the field of precision medicine by pinpointing biomarkers for diagnosis, prognosis and response to treatment, and by addressing the underlying molecular heterogeneity by identifying underpinnings associated with disease subgroups and with clinically relevant parameters. Ultimately this work may lead to rapid and reliable testing that is deployed bedside to provide better patient care for optimal treatment strategies and outcomes.