Health Sciences Clinical Associate Professor
Zarir E. Karanjawala is not currently accepting new patients. For assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Dr. Karanjawala is committed to providing the best possible patient care in our community using the most advanced tools in hematopathology.
Dr. Karanjawala is a board certified anatomic and clinical pathologist with additional specialization and board certification in hematopathology. He has a special interest in adult and pediatric hematologic malignancy and reactive conditions, including bone marrow and lymph node pathology, as well as flow cytometry.
Dr. Karanjawala's research interests focus on hematopathology, especially lymphoma, acute leukemia, plasma cell neoplasms, histiocytic disorders and other hematologic malignancies. He also has an interest in integrating molecular pathology into hematopathology diagnosis.
Pathology
B.A., Biochemistry, Occidental College, Los Angeles CA 1994
M.D., Keck School of Medicine, University of Southern California, Los Angeles CA 2004
Ph.D., Keck School of Medicine, University of Southern California, Los Angeles CA 2004
Anatomic and Clinical Pathology, Johns Hopkins Hospital, Baltimore MD 2004-2008
Hematopathology, Johns Hopkins Hospital, Baltimore MD 2008-2009
Joseph Eggleston Award for Surgical Pathology Research, Johns Hopkins School of Medicine, 2007
Irving I. Lasky, M.D. Award for Excellence in Medical Research, University of Southern California, 2004
Heidelberger Memorial Predoctoral Scholarship, University of Southern California, 2002
Outstanding Graduate Student, Department of Pathology, University of Southern California, 2002
Predoctoral Intramural Training Award, National Institutes of Health (NIH), 1994
Kuo DZ, Milstone AM, Omokaro SO, Friedman AD, Karanjawala ZE, Borowitz M, Joyner ML, Halsey NA, Sibinga EM. Epstein-Barr virus-associated central nervous system lymphoproliferative disease in a patient with acquired immunodeficiency syndrome responsive to highly active antiretroviral therapy. Clin Infect Dis. 2008 May 1;46(9):1476-8. doi:10.1086/587111. PMID:18419459.
Karanjawala ZE, Illei PB, Ashfaq R, Infante JR, Murphy K, Pandey A, Schulick R, Winter J, Sharma R, Maitra A, Goggins M, Hruban RH. New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. Am J Surg Pathol. 2008 Feb;32(2):188-96. doi:10.1097/PAS.0b013e31815701f3. PMID:18223320.
Lieber MR, Karanjawala ZE. Ageing, repetitive genomes and DNA damage. Nat Rev Mol Cell Biol. 2004 Jan;5(1):69-75. doi:10.1038/nrm1281. PMID:14708011.
Karanjawala ZE, Hinton DR, Oh E, Hsieh CL, Lieber MR. Developmental retinal apoptosis in Ku86-/- mice. DNA Repair (Amst). 2003 Dec 9;2(12):1429-34. doi:10.1016/j.dnarep.2003.08.011. PMID:14642570.
Karanjawala ZE, Hsieh CL, Lieber MR. Overexpression of Cu/Zn superoxide dismutase is lethal for mice lacking double-strand break repair. DNA Repair (Amst). 2003 Mar 1;2(3):285-94. doi:10.1016/s1568-7864(02)00218-5. PMID:12547391.
Karanjawala ZE, Adachi N, Irvine RA, Oh EK, Shibata D, Schwarz K, Hsieh CL, Lieber MR. The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants. DNA Repair (Amst). 2002 Dec 5;1(12):1017-26. doi:10.1016/s1568-7864(02)00151-9. PMID:12531011.
Karanjawala ZE, Murphy N, Hinton DR, Hsieh CL, Lieber MR. Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr Biol. 2002 Mar 5;12(5):397-402. doi:10.1016/s0960-9822(02)00684-x. PMID:11882291.
Karanjawala ZE, Kääriäinen H, Ghosh S, et al. Complete maternal isodisomy of chromosome 8 in an individual with an early-onset ileal carcinoid tumor. Am J Medl Genetics. 2000 Jul;93(3):207-210. doi:10.1002/1096-8628(20000731)93:3<207::aid-ajmg9>3.0.co;2-a.
Karanjawala ZE, Grawunder U, Hsieh CL, Lieber MR. The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts. Curr Biol. 1999 Dec 16-30;9(24):1501-4. doi:10.1016/s0960-9822(00)80123-2. PMID:10607596.
Karanjawala ZE, Collins FS. Genetics in the Context of Medical Practice. JAMA. 1998;280(17):1533–1534. doi:10.1001/jama.280.17.1533-JMS1104-3-1.