UC Davis research news releases
January 17, 2019
Researchers at MIND Institute at UC Davis and Rush University Medical Center have found that mavoglurant, an experimental drug known as an mGluR5 negative modulator, can positively modify a key characteristic behavior in individuals with fragile X syndrome (FXS).
January 14, 2019
When chemotherapy kills cancer cells, the debris of dead and dying cells can lead to inflammation and the surge of more cancerous cells. Newly published research on ovarian cancer, involving an anti-inflammatory compound developed in the Bruce Hammock lab at UC Davis, and tested at Harvard Medical School on mouse models, indicates that the compound not only suppresses inflammation but reduces cancer growth, acting as a “surge protector.”
UC Davis Health leads effort to digitize microscope slides for developing artificial intelligence for Alzheimer's disease, other brain disorders
December 27, 2018
When both of Brittany Dugger’s grandmothers were diagnosed with Alzheimer’s disease, it left a lasting impression and desire to better understand how the same clinical diagnosis could produce different symptoms. Now a new grant will help across multiple UC campuses.
December 26, 2018
Continuous indoor exposure to second-hand tobacco smoke triggers changes in the heart’s electrical activity, known as cardiac alternans, that can predict cardiac arrhythmia and sudden cardiac death, a new study from UC Davis Health researchers shows. The authors believe the study, conducted in mice, suggests that second-hand smoke exposure alters cells that regulate how the heart beats.
December 21, 2018
Hundreds of new genes linked to blindness and other vision disorders have been identified in a screen of mouse strains. Many of these genes are likely important in human eye vision and the results could help identify new causes of hereditary blindness in patients
UC Davis Health partners with Amgen to understand patient decisions, drive design-thinking decisions
December 20, 2018
Researchers from UC Davis Health recently partnered with Amgen Inc. on two projects to better understand the decision-making processes and educational needs of patients, providers and family caregivers to develop solutions that meet the needs of people facing serious illness.
December 10, 2018
Later-born siblings of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are at elevated risk for both disorders, a new study led by Meghan Miller, assistant professor in the Department of Psychiatry and Behavioral Sciences and at the UC Davis MIND Institute, has concluded. The findings appear today in JAMA Pediatrics.
December 3, 2018
Five UC Davis Health researchers were named in the annual Highly Cited Researchers List.
November 29, 2018
The UC Davis School of Medicine on Saturday will host the 2018 Western regional meeting of the American Physician Scientist Association.
November 27, 2018
Pediatrics associate professor and CTSC scholar Stephanie Crossen is using technology to help children better manage Type 1 diabetes.
November 26, 2018
UC Davis Health researchers have been awarded $5.2 million over four years from the National Institutes of Health to develop the first computerized model of the relationship between the nervous system and cardiovascular disease. The tool is expected to lead to new understanding of conditions such as hypertension, arrhythmia, heart failure and stroke, along with how those conditions change in response to treatment.
November 26, 2018
Of the three states that recently expanded comprehensive background check (CBC) policies to include all gun transfers, including those among private parties, only Delaware showed an overall increase in firearm background checks. Washington and Colorado had no changes, which the study authors say suggests that compliance and enforcement were incomplete.
November 20, 2018
UC Davis scientist Julie Sutcliffe and surgical oncologist Richard Bold have been awarded a $1 million “New Therapies Challenge” grant from the Pancreatic Cancer Collective in an effort to improve survival for people with the disease.
Study does not find population-level changes in firearm homicide or suicide rates in California 10 years after comprehensive background check and violent misdemeanor policies enacted
November 19, 2018
Incomplete background-check records, absence of permit-to-purchase provision, and compliance among possible explanations for findings.
November 1, 2018
Public health experts have found there is sufficient evidence that prenatal exposure to widely used insecticides known as organophosphates puts children at risk for neurodevelopmental disorders.
New therapies to treat naturally occurring eye diseases focus of $6 million grant from the National Eye Institute
October 17, 2018
Grant supports leading-edge research to better understand and develop novel regenerative therapies for vision loss and blindness
UC Davis Health's clinical trials directory recognized among most innovative at global clinical research summit
October 16, 2018
The Clinical Studies website is a resource for those who may be interested in participating in research studies at UC Davis Health. Easy-to-understand language, sharing options and online sign ups among the popular features.
October 2, 2018
Megan Dennis of the UC Davis MIND Institute and Genome Center is the recipient of the NIH Director’s New Innovator Award to study genes unique to humans that may contribute to neurodevelopmental disorders including autism.
October 1, 2018
Better, more precise care for military personnel and civilians who suffer traumatic brain injury along with burns or other forms of trauma is in the work thanks to a new grant from Department of Defense that's been awarded toresearchers and clinical care specialists at UC Davis Health.
September 19, 2018
New studies from UC Davis Health are among the first to associate fractures with systemic bone loss. They also begin the path to finding treatments that preserve long-term skeletal health and reduce susceptibility to additional fractures and, potentially, osteoporosis.
September 7, 2018
Junior faculty who are interested in pursuing careers as independent clinical researchers are invited to apply for the KL2 Mentored Career Development program.
September 6, 2018
Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD). Part of the Children’s Autism Metabolome Project (CAMP), the largest metabolomic ASD study ever attempted, these findings are a key step toward developing an ASD biomarker test. The research was published September 6 in the journal Biological Psychiatry.
University of California Firearms Violence Research Center announces call for research proposals on the prevention of firearm violence in California
September 5, 2018
UCFC, the firearm research center funded with an appropriation from the state in 2016 and housed within the Violence Prevention Research Program at UC Davis, aims to catalyze research, awarding grants of up to $10,000.
August 21, 2018
A comprehensive analysis of eight clinical trials and four cohort studies on cervical cancer screening by researchers from UC Davis and Kaiser Permanente Northwest has found that while Pap smears are still highly effective for detecting pre-cancerous cells and cancer, testing for the virus that causes these cancers also is an excellent screening tool.
August 13, 2018
Nine teams, including UC Davis stem cell researchers, pursue a cure for rare disorder with links to autism, Alzheimer's disease and cancer
August 13, 2018
Better treatments and improved screening programs that detect cancer at earlier stages led to an overall 12 percent improvement in cancer survival in California, according to a new report from the UC Davis Institute for Population Health Improvement.
August 7, 2018
Oanh Meyer’s mother Anh Le, arrived in the United States in 1975 as a Vietnam War refugee just a few days before the fall of Saigon. And while she settled in America and raised a family, the trauma of living in war-torn Vietnam throughout the conflict took a toll on her.
August 6, 2018
Researchers at UC Davis, Genentech and Foundation Medicine are the first to show that a blood-based test to assess tumor mutational burden (TMB) accurately identifies non-small cell lung cancer (NSCLC) patients who could benefit from immunotherapies called checkpoint inhibitors. The blood test offers a much less invasive and more repeatable alternative to tissue testing. The study was published online today in Nature Medicine.
July 27, 2018
The National Institute of Neurological Disorders and Stroke (NINDS) announced this week that it has renewed UC Davis Health in Sacramento for another five years as one of just two locations on the West Coast for its NeuroNEXT Network for Excellence in Neuroscience Clinical Trials.
July 24, 2018
Research reported this week by UC Davis Health Professor Rachel Whitmer showed correlations between a dementia diagnosis in women and number of children, number of miscarriages, age at the time of first menstrual period, age at the start of natural menopause and total reproductive years. “The story of estrogen and the brain is just beginning," Whitmer said.
July 23, 2018
Justin Oldham, a specialist in the genetics and treatment of interstitial lung disease, has been awarded a CHEST Foundation research grant to study bloodstream biomarkers that can help predict therapeutic outcomes for patients with different types of pulmonary fibrosis.
July 17, 2018
The MIND Institute's study of early social skills of infants and toddlers is just one of the ongoing clinical studies volunteers and patients can find on the new Study Pages website, a resource for healthy volunteers, patients and clinical investigators.
July 10, 2018
New UC Davis Health research shows that medical school graduates who attended community college are more likely to select family medicine for their residency training and to be from groups traditionally underrepresented in medicine. “If we want to expand the primary care workforce together with culturally competent care, we need to focus more on community college as an important pathway to medical school,” said lead author Efrain Talamantes.
UC Davis lung physiology student gets the chance of a lifetime: Attending a meeting with 43 Nobel Laureates
June 29, 2018
Cameron Flayer, a doctoral student in physiology and toxicology at UC Davis Health, gets tips from Laureates about being successful in science.
June 28, 2018
Using catheter-based ablation instead of medications alone reduces the risks of death and stroke in patients with the common form of heart arrhythmia known as atrial fibrillation, or AFib, new research from UC Davis physicians shows.
June 27, 2018
Researchers at the UC Davis MIND Institute have created a mouse model for maternal antibody-related (MAR) autism spectrum disorder (ASD) that closely mimics the physiology and behaviors seen in people with this form of ASD. People with MAR ASD have been exposed to maternal autoantibodies, which can react with fetal brain tissue.
June 18, 2018
Victims of crimes committed with firearms suffer greater distress compared to victims of crimes involving other weapons or no weapons at all. As such, persons victimized with a firearm may require special attention with regard to their emotional well-being. Findings from a brief research report by researchers at the UC Davis Violence Prevention Research Program (VPRP) are published in Annals of Internal Medicine.
June 13, 2018
For decades, clinicians have worried that giving too much intravenous fluid to children with diabetic ketoacidosis (DKA) may contribute to brain swelling and injury, and even death. Now, after a national study that examined more than a thousand patients with DKA, UC Davis researchers and their colleagues from around the country have shown that fluid infusion does not cause brain injury in children with DKA.
June 12, 2018
The entertainment provided by televised sporting events has a significant effect on crime in Chicago, reducing the number of violent, property and drug crime reports by as much as 25 percent during the hours of a given game, according to a study by the UC Davis Violence Prevention Research Program. The study published in the Journal of Sports Economics in May.
June 11, 2018
Researchers at UC Davis have confirmed that autologous hematopoietic stem cell transplant improves survival for people suffering from multiple myeloma, yet many potentially eligible patients never undergo the procedure.
June 5, 2018
As a freshman, Sid Ganesh had just finished a class and found herself late to an internship and career fair on campus. At the fair, Ganesh hurried from table to table, collecting flyers for each program and opportunity. She then saw the EMRAP display.
May 16, 2018
Richard Levenson, professor and vice chair for strategic technologies in the Department of Pathology and Laboratory Medicine at the UC Davis School of Medicine, has been selected Innovator of the Year for the development of Microscopy with Ultraviolet Surface Excitation, or MUSE -- a technology that obtains high-resolution images of biological tissue specimens without first requiring the time-consuming preparation of thin sections mounted on glass slides.
May 9, 2018
An exhaustive review by UC Davis researchers of more than 60 studies is the basis for new national recommendations about prostate cancer screening. The review and the findings were published May 8 in JAMA.
May 1, 2018
The All of Us Research Program officially opens for enrollment Sunday, May 6. Led by the National Institutes of Health (NIH), All of Us is an unprecedented effort to gather genetic, biological, environmental, health and lifestyle data from 1 million or more volunteer participants living in the U.S. A major component of the federal Precision Medicine Initiative, the program’s ultimate goal is to accelerate research and improve health.
May 1, 2018
A new study focused on households with asthmatic children finds that the use of high-efficiency filtration, either as part of a central air system or standalone air cleaner, improves indoor air quality. The study also found that while participants did not report reduced asthma symptoms, they did have fewer visits to doctor’s offices and hospitals for asthma care.
April 30, 2018
A common drug for treating epileptic seizures can lead to birth defects if used during pregnancy by interfering with glutamate signaling in earliest stages of nervous system development, a study by UC Davis School of Medicine researchers has found.
April 24, 2018
Research byJanine LaSalle, professor in the Department of Medical Microbiology and Immunology, the UC Davis Genome Center and MIND Institute, was published today in Nature Communications. LaSalle describes her work and the importance of the research below:
Study of firearm deaths over 16-year period in California finds shift in firearm homicides and suicides
April 23, 2018
A study of firearm deaths in California from 2000-2015 by the UC Davis Violence Prevention Research Program (VPRP) has found that firearm homicides were largely an urban problem at the start of the study period, however, falling rates in urban counties resulted in more rural areas in the central part of the state having the highest rates of firearm homicide by 2015. It also found firearm suicides in California increased slightly since the mid-2000s, were three times higher in rural counties and were highest among whites.
April 17, 2018
Researchers at the UC Davis MIND Institute have found that children with autism spectrum disorder (ASD) have reduced immune system regulation, as well as shifts in their gut microbiota. The immune deregulation appears to facilitate increased inflammation and may be linked to the gastrointestinal issues so often experienced by children with ASD. The research was published in the journal Brain, Behavior, and Immunity.
Study does not find change in firearm homicide or suicide rates through 2008 after repeal of comprehensive background check laws in two states
April 4, 2018
A study of firearm homicide and suicide rates in the 10 years after two states repealed their comprehensive background check laws in 1998 found no change in the rates of either cause of death from firearms through 2008. The repeals eliminated background check requirements for private-party transfers, but not for firearm transfers from licensed dealers.
March 20, 2018
In a striking new finding, researchers at the UC Davis MIND Institute found that typically-developing children gain more neurons in a region of the brain that governs social and emotional behavior, the amygdala, as they become adults. This phenomenon does not happen in people with autism spectrum disorder (ASD). Instead, children with ASD have too many neurons early on and then appear to lose those neurons as they become adults. The findings were published today in the journal Proceedings of the National Academy of Sciences (PNAS).
March 15, 2018
The Spanish version of a questionnaire used to assess the speech and quality-of- life of children and young adults following cleft-palate surgery has been developed by craniofacial disorder specialists at UC Davis Health and the University of Utah.
March 8, 2018
Researchers at UC Davis have shown that patients with acute myeloid leukemia (AML) who received their care at a National Cancer Institute (NCI) cancer center in California had a dramatically reduced risk of early mortality. Using data from the California Cancer Registry and the Patient Discharge Dataset, the team determined that the risk was reduced by 53 percent. These findings were reported in February in the journal Cancer.
March 7, 2018
Researchers at UC Davis Health, together with colleagues at UC San Francisco and the University of North Carolina at Chapel Hill, have found a mechanism for making HIV come out of hiding and become susceptible to anti-HIV drugs. Their study is now published in The Journal of Clinical Investigation.
March 6, 2018
Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A — or VEGFA — plays a major role in the inflammation and airway obstruction associated with asthma. The finding may eventually lead to new asthma treatments targeting VEGFA.
February 28, 2018
Lower-wage workers who receive a $1 raise call in sick less and consider themselves healthier than those who do not, new UC Davis research on minimum-wage policies shows.
February 16, 2018
For the first time, UC Davis School of Medicine has ranked in the top 20 percent of institutions in the country for research funding from the National Institutes of Health (NIH).
February 14, 2018
Angela Haczku, a leading researcher on environmental causes for airway inflammation, will receive more than $900,000 from the Tobacco Related-Disease Research Program to study chronic obstructive pulmonary disease (COPD) and ozone, a toxic component of urban smog.
February 9, 2018
Adolescent and young adult cancer survivors who are African American, poor or have public or no health insurance are far more likely to suffer from coronary artery disease, heart failure or stroke later in life than non-Hispanic white cancer survivors.
February 6, 2018
UC Davis Health is hosting the National Institutes of Health’s All of Us Journey, a traveling, hands-on exhibit to raise awareness about precision medicine and the All of Us research program.
February 5, 2018
UC Davis public health researchers are conducting a comprehensive assessment of the health effects of the Northern California fires in October 2017. They are asking one person per household in Napa, Sonoma and other counties affected by the fires to answer an online questionnaire — called the UC Davis Northern California Fire and Health Impacts Survey — about their daily lives, property and health before the fires occurred and immediately afterward, along with their current situations.
February 5, 2018
After years of investigation, researchers at UC Davis, Johns Hopkins, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph). The findings, publishing online this week in The Journal of Clinical Investigation, open new doors to someday developing vaccines to prevent staph skin infections, which account for 14 million outpatient visits, nearly 500,000 hospital admissions and $3 billion to $4 billion in inpatient health care costs in the U.S. per year.