Tokihiro Yamamoto, Ph.D.

Associate Professor




Radiation Oncology

Medical Physics

Imaging Informatics


Radiation Oncology

Locations and Contact

UC Davis Comprehensive Cancer Center

UC Davis Comprehensive Cancer Center
4501 X St.
Sacramento, CA 95817

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Additional Numbers

Physician Referrals

800-4-UCDAVIS (800-482-3284)

Clinical Interests

Dr. Yamamoto is a medical physicist providing clinical service and consultation to ensure safe and reliable delivery of radiotherapy treatment and perform commissioning and quality assurance for the equipment in the department, including linear accelerators, computed tomography (CT), and treatment planning system.

Research/Academic Interests

Dr. Yamamoto's research is focused on developing and investigating advanced imaging technologies, particularly functional/biological imaging based on computed tomography (CT) and positron emission tomography (PET), for radiotherapy treatment planning and response assessment.


Radiation Oncology

Center/Program Affiliation

UC Davis Comprehensive Cancer Center

Undergraduate School

B.S., Radiological Technology Science, Osaka University, Suita, Osaka, Japan 2002

Other School

M.S., Physics and Engineering, Osaka University, Suita, Osaka, Japan 2004

Other School

Ph.D., Medical Physics and Engineering, Osaka University, Suita, Osaka, Japan 2007


Postdoc Fellow, Department of Radiation Oncology, Medical Physics, Stanford University, Stanford CA 2007-2011

Received Basic/Translational Abstract Award, American Society for Radiation Oncology, 2016

First author of American Association of Physicists in Medicine (AAPM) annual meeting Science Council Session presentation, 2013

Scientific Presentation Award, International Workshop for Pulmonary Functional Imaging, 2011

Young Scientist Sponsorship, European Respiratory Society (ERS), 2011

First author of American Association of Physicists in Medicine (AAPM) annual meeting John S. Laughlin Science Council Research Symposium presentation, 2010

Complete list of published work in MyBibliography

Yamamoto T, Kabus S, Bal M, Keall PJ, Moran A, Wright C, Benedict SH, Holland D, Mahaffey N, Qi L, Daly ME. Four-Dimensional Computed Tomography Ventilation Image-Guided Lung Functional Avoidance Radiation Therapy: A Single-Arm Prospective Pilot Clinical Trial. Int J Radiat Oncol Biol Phys. 2023 Apr 1;115(5):1144-1154. doi:10.1016/j.ijrobp.2022.11.026. Epub 2022 Nov 24. PMID:36427643.

Moran A, Wang Y, Dyer BA, Yip SSF, Daly ME, Yamamoto T. Prognostic Value of Computed Tomography and/or 18F-Fluorodeoxyglucose Positron Emission Tomography Radiomics Features in Locally Advanced Non-small Cell Lung Cancer. Clin Lung Cancer. 2021 Sep;22(5):461-468. doi:10.1016/j.cllc.2021.03.015. Epub 2021 Mar 27. PMID:33931316.

Li Z, Le Roux PY, Callahan J, Hardcastle N, Hofman MS, Siva S, Yamamoto T. Quantitative assessment of ventilation-perfusion relationships with gallium-68 positron emission tomography/computed tomography imaging in lung cancer patients. Phys Imaging Radiat Oncol. 2022 Apr 11;22:8-12. doi:10.1016/j.phro.2022.03.005. PMID:35465222.

Fujita Y, Kent M, Wisner E, Johnson L, Stern J, Qi L, Boone J, Yamamoto T. Combined Assessment of Pulmonary Ventilation and Perfusion with Single-Energy Computed Tomography and Image Processing. Acad Radiol. 2021 May;28(5):636-646. doi:10.1016/j.acra.2020.04.004. Epub 2020 Jun 10. PMID:32534966.

Dyer BA, Campos DD, Hernandez DD, Wright CL, Perks JR, Lucero SA, Bewley AF, Yamamoto T, Zhu X, Rao SS. Characterization and clinical validation of patient-specific three-dimensional printed tissue-equivalent bolus for radiotherapy of head and neck malignancies involving skin. Phys Med. 2020 Sep;77:138–145. doi:10.1016/j.ejmp.2020.08.010. Epub 2020 Aug 20. PMID:32829102.

Nakajima Y, Kadoya N, Kimura T, Hioki K, Jingu K, Yamamoto T. Variations Between Dose-Ventilation and Dose-Perfusion Metrics in Radiation Therapy Planning for Lung Cancer. Advan Radiat Oncol. 2020 May-Jun;5(3):459–465. doi:10.1016/j.adro.2020.03.002. Published online 2020 Mar 20.

Shin DS, Kang SH, Kim KH, Kim TH, Kim DS, Chung JB, Lucero SA, Suh TS, Yamamoto T. Development of a deformable lung phantom with 3D-printed flexible airways. Med Phys. 2020 Mar;47(3):898–908. doi:10.1002/mp.13982. Epub 2020 Jan 20. PMID:31863479.

Yuan Z, Rong Y, Benedict SH, Daly ME, Qiu J, Yamamoto T. "Dose of the day" based on cone beam computed tomography and deformable image registration for lung cancer radiotherapy. J App Clin Med Phys. 2020 Jan;21(1):88–94. doi:10.1002/acm2.12793. Epub 2019 Dec 9. PMID:31816170.

Shi L, Rong Y, Daly M, Dyer B, Benedict S, Qiu J, Yamamoto T. Cone-beam computed tomography-based delta-radiomics for early response assessment in radiotherapy for locally advanced lung cancer. Phys Med Biol. 2020 Jan 9;65(1):015009. doi:10.1088/1361-6560/ab3247. PMID:31307024.