Boryana Stamova, Ph.D.

Boryana Stamova, Ph.D.

Department

Neurology

Title

  • Associate Adjunct Professor

Reviews

Research/Academic Interests

Dr. Stamova's research focuses on deciphering how gene expression networks change in neurological diseases and neurodevelopmental disorders to ultimately pinpoint clinically useful biomarkers and determinants of pathogenesis, pathophysiology, and etiology.

She and her colleagues have studied the molecular changes in ischemic stroke, intracerebral hemorrhage, Alzheimer's Disease and Autism Spectrum Disorders. Another main interest of Dr. Stamova's research in how modifying factors, such as biological sex and age affect the molecular response in disease. 

Education

Ph.D., Genetics, UC Davis, Davis CA 2007

B.S., University of Sofia ((Sv. Kliment Ohridski), Sofia, Bulgaria 1996

Fellowships

Neurology, Post-Doctoral Scholar, Human Transcriptomic Studies, UC Davis, Davis CA 2007-2011

Select Recent Publications

Schumann, C. M., F. R. Sharp, B. P. Ander & B. Stamova. Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain. Mol Autism. 2017; 8, 4.

Dykstra-Aiello, C., G. C. Jickling, B. P. Ander, N. Shroff, X. Zhan, D. Liu, H. Hull, M. Orantia, B. S. Stamova* & F. R. Sharp* Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci. Stroke. 2016;47, 2896-2903. *Co-Senior Authors.

Zhan, X., B. Stamova, L. W. Jin, C. DeCarli, B. Phinney & F. R. Sharp. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016;87, 2324-2332.

Dykstra-Aiello, C., G. C. Jickling, B. P. Ander, X. Zhan, D. Liu, H. Hull, M. Orantia, C. Ho & B. Stamova. Intracerebral Hemorrhage and Ischemic Stroke of Different Etiologies Have Distinct Alternatively Spliced mRNA Profiles in the Blood: a Pilot RNA-seq Study. Transl Stroke Res. 2015;6, 284-9.

Stamova, B., G. C. Jickling, B. P. Ander, X. Zhan, D. Liu, R. Turner, C. Ho, J. C. Khoury, C. Bushnell, A. Pancioli, E. C. Jauch, J. P. Broderick & F. R. Sharp. Gene expression in peripheral immune cells following cardioembolic stroke is sexually dimorphic. PLoS One. 2014;, 9, e102550.

Stamova, B. S., Y. Tian, C. W. Nordahl, M. D. Shen, S. Rogers, D. G. Amaral & F. R. Sharp. Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders. Mol Autism. 2013;4, 30.

Jickling, G. C., B. P. Ander, B. Stamova, X. Zhan, D. Liu, L. Rothstein, P. Verro, J. Khoury, E. C. Jauch, A. M. Pancioli, J. P. Broderick & F. R. Sharp. RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke. Ann Neurol. 2013;74, 232-40.

Stamova*, B., Y. Tian*, G. Jickling, C. Bushnell, X. Zhan, D. Liu, B. P. Ander, P. Verro, V. Patel, W. C. Pevec, N. Hedayati, D. L. Dawson, E. C. Jauch, A. Pancioli, J. P. Broderick & F. R. Sharp. The X-chromosome has a different pattern of gene expression in women compared with men with ischemic stroke. Stroke. 2012;43, 326-34. *Co-First Authors.

Tian*, Y., B. Stamova*, G. C. Jickling, D. Liu, B. P. Ander, C. Bushnell, X. Zhan, R. R. Davis, P. Verro, W. C. Pevec, N. Hedayati, D. L. Dawson, J. Khoury, E. C. Jauch, A. Pancioli, J. P. Broderick & F. R. Sharp. Effects of gender on gene expression in the blood of ischemic stroke patients. J Cereb Blood Flow Metab. 2012;32, 780-91. *Co-First Authors.

Stamova, B., H. Xu, G. Jickling, C. Bushnell, Y. Tian, B. P. Ander, X. Zhan, D. Liu, R. Turner, P. Adamczyk, J. C. Khoury, A. Pancioli, E. Jauch, J. P. Broderick & F. R. Sharp. Gene expression profiling of blood for the prediction of ischemic stroke. Stroke. 2010;41, 2171-7.