Lara Louise Zimmermann, M.D.
- Assistant Professor, Departments of Neurological Surgery and Neurology
- Director of Neurocritical Care
- Director of Interprofessional Education and Collaborative Practice, UC Davis School of Medicine
Philosophy of Care
Every person deserves high-quality medical care provided by specialized physicians and surgeons, working together to deliver personalized and individualized care. It is both my responsibility and my privilege to educate patients and their families daily while in the intensive care unit so that they are well-informed about their treatment options.
My goal is to be able to offer leading-edge therapies and research trial opportunities that may help both my patients today and improve care in the future.
Dr. Zimmermann is a neurologist and neurocritical care specialist who treats patients with life-threatening neurological and neurosurgical diseases, and patients with neurological manifestations of systemic diseases.
She has special expertise in the application of multimodal neuromonitoring to optimize and individualize therapies for patients with traumatic brain injury, stroke, intracerebral hemorrhage, subarachnoid hemorrhage and seizures.
Multimodal neuromonitoring includes structural and functional brain imaging combined with intracranial pressure monitoring, brain tissue oxygen monitoring, cerebral microdialysis and continuous electroencephalography used to prevent further injury and optimize recovery.
Dr. Zimmermann’s research focuses on clinical trials to optimize care and prevent ongoing brain injury following head trauma. She has a particular interest in understanding how and why seizures develop after head trauma and preventing post-traumatic epilepsy. She also has an interest in education and plays an active role developing Emergency Neurological Life Support (ENLS), a course designed to standardize and improve emergency neurological care around the world.
M.D., David Geffen School of Medicine at UCLA, Los Angeles CA 2010
B.S., Cognitive Science, UCLA, Los Angeles CA 2005
Internship: Internal Medicine, Cedars Sinai Medical Center, Los Angeles CA 2010-2011
Neurology, UC San Francisco, San Francisco CA 201-2014
Neurocritical Care, UCLA, Los Angeles CA 2014-2016
American Board of Psychiatry and Neurology - Neurology,
American Board of Psychiatry and Neurology, Neurocritical Care,
Emergency Neurological Life Support (ENLS) - Train the Trainer,
United Council of Neurologic Subspecialties - Neurocritical Care,
Neurocritical Care Society
Honors and Awards
Neurocritical Care Society Presidential Citation, 2015, 2017, 2018
UC Davis Dean�s Team Award for Excellence in Education, 2016
Nursing Excellence Award in the category of �Friends of Nursing�, 2021
Select Recent Publications
Zhou W, Kholiqov O, Zhu J, Zhao M, Zimmermann LL, Martin RM, Lyeth BG, Srinivasan VJ. Functional interferometric diffusing wave spectroscopy of the human brain. Sci Adv. 2021 May 12;7(20):eabe0150. doi:10.1126/sciadv.abe0150. PMID:33980479.
Castillo R, Chan A, Atallah S, Derry K, Baje M, Zimmermann LL, Martin R, Groysman L, Stern-Nezer S, Minokadeh A, Nova A, Huang W, Cang W, Schomer K. Treatment of adults with intracranial hemorrhage on apixaban or rivaroxaban with prothrombin complex concentrate products. J Thromb Thrombolysis. 2021 Jan;51(1):151-158. doi:10.1007/s11239-020-02154-z. Erratum in: J Thromb Thrombolysis. 2020 Jun 23;: Erratum in: J Thromb Thrombolysis. 2020 Oct 31;: PMID:32500220.
Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann L, Saigal R, Ding Q, Hirschi R, Zeiler FA, Ferguson AR, Manley GT. Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients: Insights into Normal Values and a Potential Treatment Threshold. JAMA Neurol. 2020 Sep 1;77(9):1150-1158. doi:10.1001/jamaneurol.2020.1310. Erratum in: JAMA Neurol. 2020 Sep 1;77(9):1179. PMID:32539101.
Cook AM, Morgan Jones G, Hawryluk GWJ, Mailloux P, McLaughlin D, Papangelou A, Samuel S, Tokumaru S, Venkatasubramanian C, Zacko C, Zimmermann LL, Hirsch K, Shutter L. Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients. Neurocrit Care. 2020 Jun;32(3):647-666. doi:10.1007/s12028-020-00959-7. PMID:32227294.
Zimmermann LL, Tran DS, Lovett ME, Mangat HS. Emergency Neurological Life Support Traumatic Brain Injury Protocol Version 4.0. Neurocritical Care Society. 2019 Oct.
Wilson MR, Sample HA, Zorn KC, Arevalo S, Yu G, Neuhaus J, Federman S, Stryke D, Briggs B, Langelier C, Berger A, Douglas V, Josephson SA, Chow FC, Fulton BD, DeRisi JL, Gelfand JM, Naccache SN, Bender J, Dien Bard J, Murkey J, Carlson M, Vespa PM, Vijayan T, Allyn PR, Campeau S, Humphries RM, Klausner JD, Ganzon CD, Memar F, Ocampo NA, Zimmermann LL, Cohen SH, Polage CR, DeBiasi RL, Haller B, Dallas R, Maron G, Hayden R, Messacar K, Dominguez SR, Miller S, Chiu CY. Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis. N Engl J Med. 2019 Jun 13;380(24):2327-2340. doi:10.1056/NEJMoa1803396. PMID:31189036.
Liu X, Zimmermann LL, Ho N, Vespa P, Liao X, Hu X. Cerebral Vascular Changes During Acute Intracranial Pressure Drop. Neurocrit Care. 2019 Jun;30(3):635-644. doi:10.1007/s12028-018-0651-4. PMID:30523541.
Hirschi R, Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann LL, Saigal R, Ding Q, Ferguson AR, Manley G. Analysis of high-frequency PbtO2 measures in traumatic brain injury: insights into the treatment threshold. J Neurosurg. 2018 Oct 1:1-11. doi:10.3171/2018.4.JNS172604. Epub ahead of print. PMID:30497191.
Zimmermann LL, Martin RM, Girgis F. Treatment options for posttraumatic epilepsy. Curr Opin Neurol. 2017 Dec;30(6):580-586. doi:10.1097/WCO.0000000000000505. PMID:29049053.
Zimmermann LL, Diaz-Arrastia R, Vespa PM. Seizures and the Role of Anticonvulsants After Traumatic Brain Injury. Neurosurg Clin N Am. 2016 Oct;27(4):499-508. doi:10.1016/j.nec.2016.06.001. PMID:27637399.