Brittany Nicole Dugger, Ph.D.
Neuropathology of Neurodegenerative Diseases
- Assistant Professor
Throughout her career Dr. Dugger has been the interface to the fields of neurology and neuropathology and has focused on clinicopathological correlates to investigate disease heterogeneity.
Her research focuses on:
- Understanding heterogeneity within neurodegenerative diseases.
- Understanding the interaction of peripheral changes to aging and neurodegenerative diseases.
Ph.D., Neurobiology of Disease, Mayo Clinic Graduate School, Jacksonville FL 2011
B.S., Michigan State University, East Lansing MI 2005
Neuropathology, Banner Sun Health Research Institute, Sun City AZ 2011-2013
Honors and Awards
Movement Disorders Journal 2016 Original Research Article of the Year, 2017
Parkinson's Action Network Forum Fellowship, 2014
Parkinson's Action Network Postdoctoral Advocacy Award, 2013
Asao Hirano Award for Best Paper in Neurodegenerative Diseases, American Association of Neuropathologists, 2013
Parkinson's Action Network Forum Fellowship, 2013
Select Recent Publications
Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice. J Pharmacol Exp Ther. 2016 358(3):537-47.
Dugger BN, Whiteside CM, Maarouf CL, Walker DG, Beach TG, Sue LI, Garcia A, Dunckley T, Meechoovet B, Reiman EM, Roher AE. The presence of select tau species in human peripheral tissues and their relation to Alzheimer’s disease. J Alzheimers Dis. 2016. 51(2) 345-356.
Dugger BN, Malek-Ahmadi M, Monsell SE, Kukull WA, Woodruff B, Reiman EM, Beach TG, Wilson J. Cross-sectional analysis of late life cardiovascular factors and their relation to clinically defined neurodegenerative diseases. Alzheimer Dis Assoc Disord. 2016. 30(3):223-9.
Dugger BN, Adler CH, Shill HA, Caviness J, Jacobson S, Driver-Dunckley E, Beach TG. Concomitant Pathologies among a Spectrum of Parkinsonian Disorders. Parkinsonism Relat Disord. 2014. 20(5):525-9.
Adler CH, Beach TG, Hentz JG, Shill HA, Caviness JN, Driver-Dunckley E, Sabbagh MN, Sue LI, Jacobson SA, Belden CM, Dugger BN. Low Clinical Diagnostic Accuracy of Early vs Advanced Parkinson Disease: Clinicopathologic Study. Neurology. 2014. 83(5):406-12.
Dugger BN, Clark CM, Serrano G, Mariner M, Bedell BJ, Coleman RE, Doraiswamy PM, Lu M, Fleisher AS, Reiman EM, Sabbagh MN, Sadowsky CH, Schneider JA, Zehntner SP, Carpenter AP, Joshi AD, Mintun MA, Pontecorvo MJ, Skovronsky DM, Sue LI, Beach TG. Neuropathologic heterogeneity does not impair florbetapir-PET postmortem correlates. J. Neuropath Exp Neurol. 2014. 73(1):72-80.
Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG. Clinicopathological Outcomes of Prospectively Followed Normal Elderly Brain Bank Volunteers. J. Neuropath Exp Neurol. 2014. 73(3):244-52.
Dugger BN, Boeve BF, Murray ME, Uchikado H, Parisi JE, Dickson DW, Ferman TJ. Rapid Eye Movement sleep behavior disorder and clinical subtypes in pathologically confirmed dementia with Lewy bodies. Mov. Disord. 2012. 27(1):72-78.
Dugger BN, Dickson DW. Pathology of Neurodegenerative Diseases. Cold Spring Harb Perspect Biol. 2017
Dugger BN, Perl DP, and Carlson GA. Neurodegenerative Disease Transmission and Transgenesis in Mice. Cold Spring Harb Perspect Biol. 2017