Anthony Karnezis, M.D., P.h.D.

Anthony Nicholas Karnezis, M.D., P.h.D.


Pathology - Anatomic


Surgical Pathology


  • Associate Professor


To see if Anthony Nicholas Karnezis is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Pathology Building

4400 V St.
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Phone: 800-2-UCDAVIS
Clinic Phone: 916-734-2525


Anatomic Pathology


M.D., Northwestern University Medical School, Chicago IL 1996

Ph.D., Albert Einstein College of Medicine of Yeshiva University, Bronx NY 2002

B.A., Northwestern University, Chicago IL 1992


Anatomical Pathology, University of California San Francisco, San Francisco CA 2002-2004

Gynecologic Pathology Research Fellow, University of California San Francisco, San Francisco CA 2010-2012


Anatomic Pathology Fellow, University of California San Francisco, San Francisco CA 2012-2013

Postdoctoral Fellow, University of California San Francisco, San Francisco CA 2005-2010

Board Certifications

American Board of Pathology,

California Medical License,

Fellow of the Royal College of Physicians and Surgeons of Canada,

Professional Memberships

American Association of Cancer Research

International Society of Gynecological Pathologists

U.S. and Canadian Academy of Pathology

Honors and Awards

Best Oral Presentation - Canadian Conference on Ovarian Cancer Research - 2014, 2014

Travel Award - Canadian Conference on Ovarian Cancer Research - 2014, 2014

Resident Teaching Award - UCSF Department of Pathology - 2013, 2013

Alpha Omega Alpha National Medical Honor Society - 1995, 1995

Select Recent Publications

Magrill J, Karnezis AN, Tessier-Cloutier B, Talhouk A, Kommoss S, Cochrane D, Chow C, Cheng A, Soslow R, Hauptmann S, du Bois A, Pfisterer J, Gilks CB, Huntsman DG, Kommoss F. Tubo-Ovarian. Transitional Cell Carcinoma and High-grade Serous Carcinoma Show Subtly Different Immunohistochemistry Profiles. Int J Gynecol Pathol. 2018 Jul 27; doi: 10.1097/PGP.0000000000000538. [Epub ahead of print] PubMed PMID: 30059451.

Kommoss FK, Karnezis AN, Kommoss F, Talhouk A, Taran FA, Staebler A, Gilks CB, Huntsman DG, Krämer B, Brucker SY, McAlpine JN, Kommoss S. L1CAM further stratifies endometrial carcinoma patients with no specific molecular risk profile. Br J Cancer. 2018 Jul 27; doi: 10.1038/s41416-018-0187-6. [Epub ahead of print] PubMed PMID: 30050154.

Zhang AW, McPherson A, Milne K, Kroeger DR, Hamilton PT, Miranda A, Funnell T, Little N, de Souza CPE, Laan S, LeDoux S, Cochrane DR, Lim JLP, Yang W, Roth A, Smith MA, Ho J, Tse K, Zeng T, Shlafman I, Mayo MR, Moore R, Failmezger H, Heindl A, Wang YK, Bashashati A, Grewal DS, Brown SD, Lai D, Wan ANC, Nielsen CB, Huebner C, Tessier-Cloutier B, Anglesio MS, Bouchard-Côté A, Yuan Y, Wasserman WW, Gilks CB, Karnezis AN, Aparicio S, McAlpine JN, Huntsman DG, Holt RA, Nelson  BH, Shah SP. Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer Cell. 2018 Jun 14;173(7):1755-1769.e22. doi: 10.1016/j.cell.2018.03.073. Epub 2018 May 10; PubMed PMID: 29754820.

Kuwahara Y, Kennedy LM, Karnezis AN, Mora-Blanco EL, Rogers AB, Fletcher CD, Huntsman DG, Roberts CWM, Rathmell WK, Weissman BE. High Frequency of Ovarian Cyst Development in Vhl(2B/+); Snf5(+/-) Mice. Am J Pathol. 2018 Jul; 188(7):1510-1516. doi: 10.1016/j.ajpath.2018.03.010. Epub 2018 Apr 22. PubMed PMID: 29684361; PubMed Central PMCID: PMC6024179.

Wang Y, Karnezis AN, Magrill J, Tessier-Cloutier B, Lum A, Senz J, Gilks CB, McCluggage WG, Huntsman DG, Kommoss F. DICER1 hot-spot mutations in ovarian gynandroblastoma. Histopathology. 2018 Aug;73(2):306-313. doi: 10.1111/his.13630. Epub 2018 Jun 5. PubMed PMID: 29660837.

Lang JD, Hendricks WPD, Orlando KA, Yin H, Kiefer J, Ramos P, Sharma R, Pirrotte P, Raupach EA, Sereduk C, Tang N, Liang WS, Washington M, Facista SJ, Zismann VL, Cousins EM, Major MB, Wang Y, Karnezis AN, Sekulic A, Hass R, Vanderhyden BC, Nair P, Weissman BE, Huntsman DG, Trent JM. Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition. Clin Cancer Res. 2018 Apr 15;24(8):1932-1943. doi: 10.1158/1078-0432.CCR-17-1928. Epub 2018 Feb 9. PubMed PMID: 29440177.

Kommoss S, McConechy MK, Kommoss F, Leung S, Bunz A, Magrill J, Britton H, Kommoss F, Grevenkamp F, Karnezis A, Yang W, Lum A, Krämer B, Taran F, Staebler A, Lax S, Brucker SY, Huntsman DG, Gilks CB, McAlpine JN, Talhouk A. Final validation of the ProMisE molecular classifier for endometrial carcinoma in a large population-based case series. Ann Oncol. 2018 May 1;29(5):1180-1188. doi: 10.1093/annonc/mdy058. PubMed PMID: 29432521.

Nazeran T, Cheng AS, Karnezis AN, Tinker AV, Gilks CB. Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome. Int J Gynecol Pathol. 2018 Feb 5; doi: 10.1097/PGP.0000000000000489. [Epub ahead of print] PubMed PMID: 29406447.

Garg K, Karnezis AN, Rabban JT. Uncommon hereditary gynecological tumor syndromes: pathological features in tumors that may predict risk for a germline mutation. Pathology. 2018 Feb;50(2):238-256. doi: 10.1016/j.pathol.2017.10.009. Epub 2018 Jan 17. Review. PubMed PMID: 29373116.

Karnezis AN, Leung S, Magrill J, McConechy MK, Yang W, Chow C, Kobel M, Lee CH, Huntsman DG, Talhouk A, Kommoss F, Gilks CB, McAlpine JN. Evaluation of endometrial carcinoma prognostic immunohistochemistry markers in the context of molecular classification. J Pathol Clin Res. 2017 Oct 14;3(4):279-293. doi: 10.1002/cjp2.82. eCollection 2017 Oct. PubMed PMID: 29085668; PubMed Central PMCID: PMC5653931.