Philosophy of Care
Nothing gives me greater honor than to care for critically ill children and their families. It is my hope to provide them with not only the best but also the most compassionate care possible. This would not be possible without the wonderful team of physicians, nurses and other support staff I have the privilege of working with here at the Children's Hospital.
Dr. Signoff's academic interests include graduate medical education, interprofessional education and teamwork.
Pediatric Critical Care
M.D., University of Pittsburgh School of Medicine, Pittsburgh PA 2010
B.A., Biochemistry, University of Pennsylvania, Philadelphia PA 2005
Pediatrics, Children's National Medical Center, Washington DC 2010-2013
Pediatric Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia PA 2013-2016
American Board of Pediatrics,
American Board of Pediatrics, Pediatric Critical Care Medicine,
Alpha Omega Alpha
American Academy of Pediatrics
Society of Critical Care Medicine
Honors and Awards
Jean A. Cortner Divisional Teaching Award, Children's Hospital of Philadelphia, 2013, 2014, 2015
Excellence in Teaching Award, George Washington University School of Medicine, 2011, 2012
Select Recent Publications
Barseghyan K, Ben-Isaac E, Parikh K, Signoff J, DeBiasi RL, Patel D, Chhabra A, Davies HD, Patel S, Sigal Y. Index of suspicion. Case 1: Anasarca in a 2-year-old boy. Case 2: Daily spiking fevers in an 8-year-old girl. Case 3: Poor weight gain and excessive sleepiness in a 7-week-old girl. Pediatr Rev. 2014 Jan;35(1):42-7. doi:10.1542/pir.35-1-42. PMID:24385565.
Fujita T, Igarashi J, Okawa ER, Gotoh T, Manne J, Kolla V, Kim J, Zhao H, Pawel BR, London WB, Maris JM, White PS, Brodeur GM. CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. J Natl Cancer Inst. 2008 Jul 2;100(13):940-9. doi:10.1093/jnci/djn176. Epub 2008 Jun 24. PMID:18577749.