Technological advancements in viral vector delivery and epigenome editing has vastly increased our ability to make the ‘undruggable’ genome ‘druggable’. My lab focuses on a basic science approach to "big data"-driven design of novel tools for epigenome editors that elucidate the role of chromatin biology in neurodevelopmental disorders to remove some of the key constraints currently hampering translation of such methods.
Epigenome Editing Lab
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Principal InvestigatorJulian Halmai, Ph.D., M.Sc.
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Our Research Goals
My lab’s research goals are to investigate the role of modulating epigenetic signatures in neurodevelopmental disease, build foundational ‘omics’ datasets, and develop novel tools to advance clinical therapies for those currently suffering from untreatable childhood neurological disorders.
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Current Projects
- Reactivation of X-linked target genes using CRISPR technology
- Gene therapy for neurodevelopmental disorders
- Transcriptome analysis of neurodevelopmental disorders
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Our Team
- Viktoria Haghani, postdoctoral scholar
- Camille Loret, postdoctoral scholar
- Yomira Palacios, graduate student Neuroscience
- Nik Lind, graduate student Biomedical Engineering
- Anber Ansari, graduate student Integrative Genetics and Genomics
Clinical Trials
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Fellowship Programs and Training Opportunities
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