Assistant Professor, Department of Neurology
Assistant Professor, Department of Biomedical Engineering
To see if Audrey Peiwen Fan is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Magnetic Resonance Imaging
I'm an engineer at the interface of medical technology, signal processing, and neuroscience. I have a deep passion for teaching, and strive to help trainees utilize analytical and research skills to create impactful biomedical tools that help patients.
I also believe there is a strong link between the beauty of art and science, love Chinese brush painting, and have years of volunteer experience at art museums.
Dr. Audrey Fan is a Ph.D. imaging physicist and translational scientist. She develops novel magnetic resonance imaging (MRI) and positron emission tomography (PET) methods to study brain physiology in cerebrovascular disease and vascular dementia. She has translated new imaging technologies to patient studies in acute stroke, Moyamoya disease and intracranial stenosis.
Dr. Fan serves as co-director of the Imaging Core for UC Davis Health's Alzheimer’s Disease Center, a National Institutes of Health-funded Alzheimer’s research center.
Dr. Fan's research mission is to develop advanced, multi-modal imaging tools to understand the vascular and physiological bases of neurological disorders. Through new MRI and PET imaging technologies, she aims to diagnose cerebrovascular disease and dementia earlier than ever, and identify optimal therapies to improve patient quality of life.
B.S., Stanford University, Stanford CA
Ph.D., Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge MA
Radiology, Instructor, Stanford University, Stanford CA
Radiology, Postdoctoral Fellow, Stanford University, Stanford CA
K99/R00 Pathway to Independence Award, National Institutes of Neurological Disease and Stroke (2018-2023), 2020
CECI2 Early Career Investigator, Academy of Radiology Research, 2019
Junior Fellow of the International Society for Magnetic Resonance in Medicine (ISMRM), 2018
Distinguished Reviewer, Magnetic Resonance in Medicine, 2017, 2018, 2019
Outstanding Teacher Award, ISMRM, 2018
Summa Cum Laude Merit Award, ISMRM, 2012, 2015, 2016, 2018
Stanford Neuroscience Institute Interdisciplinary Scholar Award, 2015, 2016, 2017
National Science Foundation Graduate Research Fellowship, 2010, 2011, 2012, 2013
Helen Carr Peake Research Prize, Massachusetts Institute of Technology, 2013
Best Poster Award, Gordon-Kenan Research Seminar on Brain Metabolism and Blood Flow, 2012
Guo J, Gong E, Fan AP, Goubran M, Khalighi MM, Zaharchuk G. Predicting 15O-Water PET cerebral blood flow maps from multi-contrast MRI using a deep convolutional neural network with evaluation of training cohort bias. J Cereb Blood Flow Metab. 2020 Nov;40(11):2240-2253. doi:10.1177/0271678X19888123. Epub 2019 Nov 13. PMID:31722599.
Fan AP, Khalil AA, Fiebach JB, Zaharchuk G, Villringer A, Villringer K, Gauthier CJ. Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke. J Cereb Blood Flow Metab. 2020 Mar;40(3):539-551. doi:10.1177/0271678X19827944. Epub 2019 Feb 7. PMID:30732551.
Ishii Y, Thamm T, Guo J, Khalighi MM, Wardak M, Holley D, Gandhi H, Park JH, Shen B, Steinberg GK, Chin FT, Zaharchuk G, Fan AP. Non-invasive quantification of cerebrovascular reactivity in patients with Moyamoya disease from O-15 water PET and phase-contrast MRI. J Magn Reson Imag. 2019. doi:10.1002/jmri.26773.
Gauthier CJ, Fan AP. BOLD signal physiology: Models and applications. Neuroimage. 2019 Feb 15;187:116-127. doi:10.1016/j.neuroimage.2018.03.018. Epub 2018 Mar 13. PMID:29544818.
Fan AP, Guo J, Khalighi MM, Gulaka PK, Shen B, Park JH, Gandhi H, Holley D, Rutledge O, Singh P, Haywood T, Steinberg GK, Chin FT, Zaharchuk G. Long-Delay Arterial Spin Labeling Provides More Accurate Cerebral Blood Flow Measurements in Moyamoya Patients: A Simultaneous Positron Emission Tomography/MRI Study. Stroke. 2017 Sep;48(9):2441-2449. doi:10.1161/STROKEAHA.117.017773. Epub 2017 Aug 1. PMID:28765286.
Fan AP, Jahanian H, Holdsworth SJ, Zaharchuk G. Comparison of cerebral blood flow measurement with [15O]-water positron emission tomography and arterial spin labeling magnetic resonance imaging: A systematic review. J Cereb Blood Flow Metab. 2016 May;36(5):842-61. doi:10.1177/0271678X16636393. Epub 2016 Mar 4. PMID:26945019.
Fan AP, Schäfer A, Huber L, Lampe L, von Smuda S, Möller HE, Villringer A, Gauthier CJ. Baseline oxygenation in the brain: Correlation between respiratory-calibration and susceptibility methods. Neuroimage. 2016 Jan 15;125:920-931. doi:10.1016/j.neuroimage.2015.11.007. Epub 2015 Nov 5. PMID:26549301.
Fan AP, Bilgic B, Gagnon L, Witzel T, Bhat H, Rosen BR, Adalsteinsson E. Quantitative oxygenation venography from MRI phase. Magn Reson Med. 2014 Jul;72(1):149-59. doi:10.1002/mrm.24918. Epub 2013 Sep 4. PMID:24006229.
Bilgic B, Fan AP, Polimeni JR, Cauley SF, Bianciardi M, Adalsteinsson E, Wald LL, Setsompop K. Fast quantitative susceptibility mapping with L1-regularization and automatic parameter selection. Magn Reson Med. 2014 Nov;72(5):1444-59. doi:10.1002/mrm.25029. Epub 2013 Nov 20. PMID:24259479.
Fan AP, Benner T, Bolar DS, Rosen BR, Adalsteinsson E. Phase-based regional oxygen metabolism (PROM) using MRI. Magn Reson Med. 2012 Mar;67(3):669-78. doi:10.1002/mrm.23050. Epub 2011 Jun 28. PMID:21713981.