Tsung-Yu Chen, M.D., M.S., Ph.D. for UC Davis Health

Tsung-Yu Chen, M.D., M.S., Ph.D.







Locations and Contact



Center/Program Affiliation

Center for Neuroscience

Medical School

M.D., National Yang-Ming Medical School, Taipei, 1986

Other School

Ph.D., Johns Hopkins University School of Medicine, Baltimore, Maryland, 1994


National Yang-Ming Medical School/Veteran General Hospital-Taipei, Taipei, 1984-86


Brandeis University, Ealtham, Massachusetts, 1994-96

Paul F. Cranefield Award, Society of General Physiologists, 2004

Michael A. Shanoff Research Award, Johns Hopkins University School of Medicine, 1994

Scholarship of Ministry of Education, Taiwan, 1989

Shun-Ro In Research Award, Yang-Ming Medical College, Taiwan., 1988

Chen T-Y, Lin Y-F., and Zheng J. (2009) Electrophysiological Measurements of Membrane Proteins. In Handbook of Modern Biophysics, Vol 1 , T. Jue ed. pp 111-145. Humana Press. New York, NY

Zhang X.-D., and Chen T.-Y (2009) Amphiphilic blockers punch through a mutant CLC-0 pore. J Gen. Physiol. 133: 59-68.

Zhang X.-D., Tseng P.-Y, Yu W.-P., and Chen T.-Y (2009) Blocking pore-open mutants of CLC-0 by amphiphilic blockers. J Gen. Physiol. 133: 43-58.

Zhang X.-D. Tseng P.-Y, and Chen T.-Y (2008) ATP inhibition of CLC-1 is controlled by oxidation and reduction. J Gen. Physiol. 132: 421-428.

Chen T.-Y, and Hwang, T.-C. (2008) CLC-0 and CFTR: Chloride channels evolved from transporters. Physiol. Rev. 88: 351-387.

Tseng P.-Y, Bennetts B., and Chen T.-Y (2007) Cytoplasmic ATP inhibition of CLC-1 is enhanced by low pH. J Gen. Physiol. 130: 217-221.

Chen, T.-Y, Takeuchi H, and Kurahashi T. (2006) Odorant inhibition of the olfactory cyclic nucleotide-gated channel with a native molecular assembly. J Gen Physiol. 128: 365-371.

Zhang X.-D., Li Y, Yu W.-P. and Chen T.-Y (2006) Roles of K149, G352 and H401 in the channel functions of CIC-0: Testing the predictions from theoretical calculations. J Gen. Physiol. 127: 435-447.

Bykova E. A., Zhang X.-D., Chen T.-Y, and Zheng 1. (2006) Large movement in the C-terminus of CLC-0 chloride channel during slow gating. Nature Struct & Mol. Biol. 13: 1115-1119.

Chen T.-Y. (2005) Structure and function of ClC channels. Ann. Rev. Physiol. 67: 809-839.

Li Y, Yu W.-P., Lin C.-W. and Chen T.-Y. (2005) Oxidation and reduction control of the inactivation gating of Torpedo ClC-0 chloride channels. Biophys. J. 88: 3936-3945.