David M. Rocke, Ph.D. for UC Davis Health

David M. Rocke, Ph.D.

Distinguished Professor, Department of Public Health Sciences and Department of Biomedical Engineering




Public Health Sciences


Locations and Contact

UC Davis School of Medicine

UC Davis School of Medicine - Medical Sciences 1C

Davis, CA 95616

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Research/Academic Interests

Dr. Rocke's research group works on methods for bioinformatics and data analysis of gene expression, proteomics, metabolomics and other high-throughput biological assays. He is the author or co-author of two scholarly books and over 200 scientific papers.



Undergraduate School

A.B., Mathematics and Physics, Shimer College, Mount Carroll IL 1966

Medical School

Ph.D., Mathematics, University of Illinois at Chicago, Chicago IL 1972

Other School

M.A., Mathematics, University of Illinois at Chicago, Chicago IL 1968

Senior Member, International Society for Computational Biology, 2016

Fellow, American Association for the Advancement of Science, 2007

Distinguished Service Award, Division of Molecular Orthopaedics, University of Pennsylvania, 2000

Elected to Membership in the International Statistical Institute, 1997

Statistics in Chemistry Award, American Statistical Association, 1997

Sundberg JP, Galantino-Homer H, Fairfield H, Ward-Bailey PF, Harris BS, Berry M, Pratt CH, Gott NE, Bechtold LS, Kaplan PR, Durbin-Johnson BP, Rocke DM, Rice RH. Witch Nails (Krt90whnl): A spontaneous mouse mutation affecting nail growth and development. PLoS One. 2022 Nov 14;17(11):e0277284. doi:10.1371/journal.pone.0277284. PMID:36374931.

Sariano PA, Mizenko RR, Shirure VS, Brandt A, Nesiri C, Shergill B, Rocke DM, Carney RP, George SC. Convection and extracellular matrix binding control small extracellular vesicle interstitial transport. bioRxiv. 2022 Aug 5. doi:10.1101/2022.08.03.502657.

Karim N, Plott TJ, Durbin-Johnson BP, Rocke DM, Salemi M, Phinney BS, Goecker ZC, Pieterse MJM, Parker GJ, Rice RH. Elucidation of familial relationships using hair shaft proteomics. Forensic Sci Int Genet. 2021 Sep;54:102564. doi:10.1016/j.fsigen.2021.102564. Epub 2021 Jul 17. PMID:34315035.

Kaplan FS, Teachey DT, Andolina JR, Siegel DM, Mancilla EE, Hsiao EC, Al Mukaddam M, Rocke DM, Pignolo RJ. Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva. Bone. 2021 Sep;150:116016. doi:10.1016/j.bone.2021.116016. Epub 2021 May 19. PMID:34022457.

Parker GJ, Buonasera T, Yip JM, Eerkens JW, Salemi M, Durbin-Johnson B, Haas R, Buikstra JE, Klaus H, Rocke DM, Phinney B. AMELY deletion is not detected in systematically sampled reference populations: A Reply to Štamfelj. J Archaeological Science. 2021 Jun;130:105354. doi:10.1016/j.jas.2021.105354.

Halloran JT, Rocke DM. GPU-Accelerated Primal Learning for Extremely Fast Large-Scale Classification. Advances in Neural Information Processing Systems. 2020 Oct 15;33:5945-5956.

Plott TJ, Karim N, Durbin-Johnson BP, Swift DP, Scott Youngquist R, Salemi M, Phinney BS, Rocke DM, Davis MG, Parker GJ, Rice RH. Age-Related Changes in Hair Shaft Protein Profiling and Genetically Variant Peptides. Forensic Sci Int Genet. 2020 Jul;47:102309. doi:10.1016/j.fsigen.2020.102309. Epub 2020 May 22. PMID:32485593.

Hackenberg KAM, Rajabzadeh-Oghaz H, Dreier R, Buchholz BA, Navid A, Rocke DM, Abdulazim A, Hänggi D, Siddiqui A, Macdonald RL, Meng H, Etminan N. Collagen Turnover in Relation to Risk Factors and Hemodynamics in Human Intracranial Aneurysms. Stroke. 2020 May;51(5):1624-1628. doi:10.1161/STROKEAHA.120.029335. Epub 2020 Mar 20. Erratum in: Stroke. 2020 May;51(5):e102. PMID:32192404.

Phillips MA, Cánovas A, Rea MA, Islas-Trejo A, Medrano JF, Durbin-Johnson B, Rocke DM, Rice RH. Deducing Signaling Pathways from Parallel Actions of Arsenite and Antimonite in Human Epidermal Keratinocytes. Sci Rep. 2020 Feb 19;10:2890. doi:10.1038/s41598-020-59577-0.

Halloran JT, Zhang H, Kara K, Renggli C, The M, Zhang C, Rocke DM, Käll L, Noble WS. Speeding Up Percolator. J Proteome Res. 2019 Sep 6;18(9):3353-3359. doi:10.1021/acs.jproteome.9b00288. Epub 2019 Aug 23. PMID:31407580.