Ian Elliott Brown, M.D., Ph.D., F.A.C.S.
Associate Professor in Residence
Ian Elliott Brown is not currently accepting new patients. For assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Locations and Contact
UC Davis Medical Center
UC Davis Medical Center - Trauma, Acute Care Surgery and Surgical Critical Care
2315 Stockton Blvd.
Sacramento, CA 95817
Phone: 800-2-UCDAVIS (800-282-3284)
UC Davis Medical Center - Cypress Building
UC Davis Medical Center - Cypress Building
2221 Stockton Blvd.
Sacramento, CA 95817
Phone: 800-2-UCDAVIS (800-282-3284)
Additional Numbers
Physician Referrals
Philosophy of Care
In trauma, often the injuries are much more than the cuts and bruises and fractures. Treating the whole patient requires true empathy and a kind of humility and willingness to consider that it is difficult to completely understand the complexity of another person's lived experience but essential to try. I like to think that we do much more than procedures and operations and that the impact of our care should extend well beyond when the patient leaves out door.
Clinical Interests
Ian Brown has abroad interest in trauma with a particular focus on acute coagulation and endotheliopathy in trauma. Additionally, he has a strong interest in curbing violence-related trauma recidivism and is a co-founder of the UC Davis Wraparound Hospital-based Violence Intervention Program.
Research/Academic Interests
Ian Elliott Brown, M.D., Ph.D., is an associate professor of surgery in the Division of Trauma, Acute Care Surgery, and surgical critical care within the Department of Surgery at the University of California Davis. In his role as a surgeon and researcher, he has two primary interests. The first is in understanding the intersection between coagulation and inflammation in the setting of acute severe trauma and how this interplay impacts outcomes through consequences of coagulopathy and endotheliopathy. The second focus is on social determinants of violence-related trauma recidivism and how hospital-based violence intervention programs (HVIP) such as the UC Davis Wraparound HVIP can disrupt cycles of violence through trauma-informed, culturally competent interventions.
He investigates the role of cell-adhesion molecules such as P-selectin in inflammatory processes and intravascular thromboembolic injury in the setting of trauma, particularly in situ pulmonary arterial thrombosis (PAT). By understanding the natural history of PAT and the role and regulation of P-selectin, By understanding the natural history of PAT and the role and regulation of P-selectin in this history, he seeks to determine the necessity of intervention and to investigate the efficacy of P-selectin blockade as an alternative to anti-coagulation for intervention. More broadly, cell adhesion molecules such as P-selectin likely play a role in thrombosis in the setting of vascular injury, vascular repair, injuries of ischemia and reperfusion, and potentially in the setting of infection and sepsis. Understanding the biology of cell adhesion molecules such as P-selectin may therefore contribute to the continuing evolution of resuscitation paradigms that improve trauma- and infection-associated outcomes.
The Wraparound HVIP incorporates trauma-informed, relationship-based mentoring, culturally affirming case management, and partnerships with natural and community supports to facilitate holistic recovery from violent injury and reduce the risk for future violence involvement. Using a mixed methods approach with quantitative and qualitative data analysis, the research group seeks to understand the social determinants that contribute to violence-related trauma and to evaluate the impact and efficacy of interventions.
Division
Division of Trauma, Acute Care Surgery and Surgical Critical Care
Center/Program Affiliation
Trauma Program
Undergraduate School
B.S., Biology, Stanford University, Palo Alto CA 1997
Medical School
M.D., University of Chicago, Pritzker School of Medicine, Chicago IL 2007
Other School
Ph.D., Immunology, University of Chicago, Chicago IL 2005
Internship
General Surgery, UC San Francisco Medical Center, San Francisco CA 2007-2008
Residency
General Surgery, UC San Francisco Medical Center, San Francisco CA 2007-2014
Fellowship
Trauma and Surgical Critical Care, UC Davis Medical Center, Sacramento CA 2014-2015
UC Davis Health Diamond Doc Award, Quarters 3 and 4 2022, UC Davis Health,
UC Davis Health Deans’ Team Award for Excellence for the Wraparound Hospital-Based Violence Intervention Program, 2021, UC Davis Health,
Fellow of the American College of Surgeons, 2021, American College of Surgeons,
UC Davis Soaring to New Heights Calvin E. Handy Leadership Award , 2021, UC Davis,
American Surgical Association Foundation Fellowship Research Award, 2020,
American Association for the Surgery of Trauma, Acute Care Surgery Research Scholarship, 2019,
UCSF Azakie-Chesson Award for Compassion in Surgery, 2014,
Kleber KT, Kravitz-Wirtz N, Buggs SL, Adams SM, Sardo AC, Hoch JS, Brown IE. Emergency department visit patterns in the recently discharged, violently injured patient: Retrospective cohort review. Am. J of Surgery (in press, accepted July 14,2022) https://doi.org/10.1016/j.amjsurg.2022.07.005
Theodorou CM, Beyer CA, Vanover MA, Brown IE, Salcedo ES, Farmer DL, Hirose S, Beres AL. The Hidden Mortality of Pediatric Firearm Violence, Journal of Pediatric Surgery. 2022 doi: https://doi.org/10.1016/j.jpedsurg.2021.12.031
Lee JSG, Brown IE, Semrad AM, Zeki AA. Getting around the gut: a unique management challenge of thyroid storm precipitated by amphetamine-associated duodenal ischaemia leading to compromised enteric absorption. BMJ Case Rep. 2021;0:e238889. doi:10.1136/bcr-2020-238889
Schutzman LM, Rigor RR, Lin YLJ, Dang AN, Le PH, Singh HB, Yu B, Wisner PH, Musson CC, Clark IJ, Galante JM, Brown IE. P-Selectin antibody treatment after blunt thoracic trauma prevents early pulmonary arterial thrombosis without changes in viscoelastic measurements of coagulation. J Trauma Acute Care Surg. 2021 Jun 1;90(6):1032-1039. doi: 10.1097/TA.0000000000003162. PMID: 34016926
Rigor RR, Schutzman LM, Galante JM, and Brown IE. Viscoelastic Coagulation Monitor (VCMVet) Reference Intervals and Sex Differences in Mature Adult Mice. Acta Haematol. 2021 Jul 8:1-8. doi: 10.1159/000516587. Online ahead of print. PMID: 34237720
Guenther TM, Spruce MW, Bach LM, Caples CM, Beyer CA, Grayson JK, Meyers FJ, Palmieri TL, Brown IE. High Versus Low Volume Fluid Resuscitation Strategies in a Porcine Model (Sus Scrofa) of Combined Thermal and Traumatic Brain Injury. Shock. 2020 Aug 31. doi: 10.1097/SHK.0000000000001658. Epub ahead of print. PMID: 32881757.
Brown IE. Comment on "The Long-term Risk of Venous Thromboembolism After Blunt Splenic Injury Managed by Embolization". Ann Surg. 2020 Mar;271(3):e101. doi:10.1097/SLA.0000000000003761. PMID:32079831.
Gao G, Chen LX, Brown IE, Mattos A, Perez RV, Jen KY. Donor characteristics, recipient outcomes, and histologic findings of kidney allografts with diffuse donor-derived glomerular fibrin thrombi. Transplantation. 2019 Sep;103(9):1921-1927. doi: 10.1097/TP.0000000000002578.
Schutzman LM, Rigor RR, Khosravi N, Galante JM, Brown IE. P-Selectin is Critical for De Novo Pulmonary Arterial Thrombosis following Blunt Thoracic Trauma. J Trauma Acute Care Surg. 2019 Apr;86(4):583-591. doi:10.1097/TA.0000000000002166.
Iverson KT, Curtis E, Salcedo E, Anderson J, Brown I. New Fragmenting Bullet Leads to Unexpected Injury Pattern: a Case Report involving the Radically Invasive Projectile. Trauma. 2018 Mar 25. doi:10.1177/1460408618759365.