Baback Roshanravan, M.D., M.S.P.H., M.S.
Associate Professor of Medicine
Baback Roshanravan is not currently accepting new patients. For assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Locations and Contact
Lawrence J. Ellison Ambulatory Care Center
Nephrology Clinic
4860 Y St.
Sacramento, CA 95817
Phone: 916-734-3761
Philosophy of Care
Dr. Roshanravan's care focuses on a patient-centered, collaborative, and interdisciplinary approach to patient care. Critical to this is listening to patient priorities and helping them maintain or improve physical functioning in their environment by working in an interdisciplinary setting with a personalized approach to patient care.
Clinical Interests
Dr. Roshanravan is a general nephrologist offering care for adults with chronic kidney disease with a special clinical interest in metabolism, hypertension and geriatric nephrology. He has particular expertise on the impact of chronic kidney disease on muscle metabolism and whole-person physical functioning and believes in a collaborative and interdisciplinary approach to patient care.
Research/Academic Interests
Dr. Roshanravan is is focused on patient-oriented research studying the links between altered metabolism in chronic kidney disease with muscle function, physical functioning, and frailty. His current research employs metabolic imaging and live tissue analysis of mitochondrial biochemistry to assess the impact of lifestyle and pharmacologic therapies on improving muscle performance, metabolism and physical function in vulnerable persons with chronic kidney disease. He is currently funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to investigate the impact of home-based exercise and treatment of metabolic acidosis on muscle metabolism and physical endurance among persons with CKD. As an investigator in the Neuromuscular Research Laboratory he leads an interdisciplinary team of investigators across UC Davis, California State University Sacramento, and Vanderbilt University Medical Center.
Division
Nephrology
Undergraduate School
B.S., Biology, UC Irvine, Irvine CA 1997
Medical School
M.D., Northwestern University, Feinberg School of Medicine, Chicago IL 2005
Other School
M.S.P.H., Parasitology, Tulane University School of Public Health and Tropical Medicine, New Orleans LA 2001
Other School
M.S., Epidemiology, University of Washington School of Public Health, Seattle WA 2012
Internship
Internal Medicine, University of Washington, Seattle WA 2005-2006
Residency
Internal Medicine, University of Washington, Seattle WA 2005-2008
Fellowship
Nephrology, University of Washington, Seattle WA 2009-2013
NIDDK Award R01DK125794 (9/20/21 - 6/30/2026): Role of Mitochondrial Dysfunction in the Response to Exercise in Patients with Advanced Kidney Disease,
NIDDK Award R01DK129793 (8/18/21- 6/30/2026): Impact of metabolic acidosis on muscle mitochondrial energetics, metabolic health and physical endurance in persons with chronic kidney disease,
Dialysis Clinics Incorporated (C-4112) (present-6/30/2022): Mitochondrial bioenergetics and physical endurance in CKD,
Paul F. Gulyassy Endowed Professorship, 2018
NIDDK Career Development Award K23 DK099442 (20013-2019): Skeletal muscle dysfunction in persons with chronic kidney disease, 2017
Roshanravan B, Liu SZ, Ali AS, Shankland EG, Goss C, Amory JK, Robertson HT, Marcinek DJ, Conley KE. In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial. PLoS One. 2021 Jul 15;16(7):e0253849. doi:10.1371/journal.pone.0253849. PMID:34264994.
Chalupsky M, Goodson DA, Gamboa JL, Roshanravan B. New insights into muscle function in chronic kidney disease and metabolic acidosis. Curr Opin Nephrol Hypertens. 2021 May 1;30(3):369-376. doi:10.1097/MNH.0000000000000700. PMID:33767065.
Gamboa JL, Roshanravan B, Towse T, Keller CA, Falck AM, Yu C, Frontera WR, Brown NJ, Ikizler TA. Skeletal Muscle Mitochondrial Dysfunction Is Present in Patients with CKD before Initiation of Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2020 Jul 1;15(7):926-936. doi:10.2215/CJN.10320819. Epub 2020 Jun 26. PMID:32591419.
Kestenbaum B, Gamboa J, Liu S, Ali AS, Shankland E, Jue T, Giulivi C, Smith LR, Himmelfarb J, de Boer IH, Conley K, Roshanravan B. Impaired skeletal muscle mitochondrial bioenergetics and physical performance in chronic kidney disease. JCI Insight. 2020 Mar 12;5(5):e133289. doi:10.1172/jci.insight.133289. PMID:32161192.
Liu SZ, Ali AS, Campbell MD, Kilroy K, Shankland EG, Roshanravan B, Marcinek DJ, Conley KE. Building strength, endurance, and mobility using an astaxanthin formulation with functional training in elderly. J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):826-833. doi:10.1002/jcsm.12318. Epub 2018 Sep 26. PMID:30259703.
Roshanravan B, Zelnick LR, Djucovic D, Gu H, Alvarez JA, Ziegler TR, Gamboa JL, Utzschneider K, Kestenbaum B, Himmelfarb J, Kahn SE, Raftery D, de Boer IH. Chronic kidney disease attenuates the plasma metabolome response to insulin. JCI Insight. 2018 Aug 23;3(16):e122219. doi:10.1172/jci.insight.122219. PMID:30135309.
Roshanravan B, Patel KV, Fried LF, Robinson-Cohen C, de Boer IH, Harris T, Murphy RA, Satterfield S, Goodpaster BH, Shlipak M, Newman AB, Kestenbaum B; Health ABC study. Association of Muscle Endurance, Fatigability, and Strength With Functional Limitation and Mortality in the Health Aging and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2017 Feb;72(2):284-291. doi:10.1093/gerona/glw210. Epub 2016 Oct 21. PMID:27907890.
Roshanravan B, Kestenbaum B, Gamboa J, Jubrias SA, Ayers E, Curtin L, Himmelfarb J, de Boer IH, Conley KE. CKD and Muscle Mitochondrial Energetics. Am J Kidney Dis. 2016 Oct;68(4):658-659. doi:10.1053/j.ajkd.2016.05.011. Epub 2016 Jun 14. PMID:27312460.
Roshanravan B, Patel KV, Robinson-Cohen C, de Boer IH, O'Hare AM, Ferrucci L, Himmelfarb J, Kestenbaum B. Creatinine clearance, walking speed, and muscle atrophy: a cohort study. Am J Kidney Dis. 2015 May;65(5):737-47. doi:10.1053/j.ajkd.2014.10.016. Epub 2014 Dec 24. PMID:25542415.
Roshanravan B, Robinson-Cohen C, Patel KV, Ayers E, Littman AJ, de Boer IH, Ikizler TA, Himmelfarb J, Katzel LI, Kestenbaum B, Seliger S. Association between physical performance and all-cause mortality in CKD. J Am Soc Nephrol. 2013 Apr;24(5):822-30. doi:10.1681/ASN.2012070702. Epub 2013 Apr 18. PMID:23599380.