Neuroimaging Research | Psychiatry and Behavioral Sciences | UC Davis Health

Multimodal neuroimaging of altered brain development in MIA models and schizophrenia

Description
The goal of this proposed research is to provide information on alterations in brain development caused by maternal immune system activation (MIA) that may precede psychosis and to establish a common developmental neuropathology across mice, monkeys and humans to lead to clinically useful biomarkers for detecting individuals at high risk for schizophrenia and promote earlier prevention and more effective treatment.

Funding
UC Davis Conte Center, funded through a grant from the National Institute of Mental Health

David G. Amaral, Ph.D.
Co-Investigator
dgamaral@ucdavis.edu

Neural and cognitive development and internalizing problems in adolescence with autism spectrum disorder

Description
This grant attempts to characterize and predict aspects of cognitive development in adolescence, to examine changes in social awareness, motivation, and functioning; and to use this information to investigate the emergence of depression between middle childhood and adolescence using functional magnetic resonance imaging (fMRI).

Funding
National Institutes of Health

David G. Amaral, Ph.D.
Co-Investigator
dgamaral@ucdavis.edu

Marjorie Solomon, Ph.D.
Co-Investigator
marsolomon@ucdavis.edu

Neurodevelopment of cognitive control in autism: adolescence to young adulthood

Description
This study examines the development of cognitive control across adolescence into young adulthood and its relationship to functional outcomes in individuals with autism spectrum disorders (ASD) using functional magnetic resonance imaging (fMRI) and behavioral measures.

Funding
National Institutes of Health / National Institute of Mental Health

Marjorie Solomon, Ph.D., M.B.A.
Principal Investigator
marsolomon@ucdavis.edu

Tara Ann Niendam, Ph.D.
Co-Investigator
tniendam@ucdavis.edu